Effects of Social Networks and Policy Context on Health among Older Sexual and Gender Minorities in the US South

社交网络和政策环境对美国南部老年性少数群体健康的影响

• 批准号: 10771859
• 负责人: Tara McKay
• 金额: $ 10万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10771859
• 关键词: Administrative Supplement; Adult; Age; Aging; Automobile Driving; Award; Biological Markers; Cognition; Cognitive aging; Collection; Cross-Sectional Studies; Data; Data Collection; Distress; Educational workshop; Elderly; Equity; Funding; Future; Gender; Goals; Health; Health Disparities Research; Health Professional; Immune; Impaired cognition; Inflammation; Infrastructure; Investments; Lesbian Gay Bisexual; Life Experience; Measures; Mentors; Mentorship; Outcome; Parents; Pathway interactions; Patient Self-Report; Persons; Policies; Population; Postdoctoral Fellow; Psyche structure; Reporting; Research; Research Personnel; Sample Size; Sampling; Sex Orientation; Sexual and Gender Minorities; Sleep disturbances; Social Network; Social Policies; Spouses; Surveys; Training; United States National Institutes of Health; Universities; Variant; Work; cisgender; cognitive ability; cognitive function; cognitive testing; diversity and inclusion; experience; gender diversity; gender minority group; gender minority health disparity; graduate student; improved; member; minority stress; research study; training opportunity; transgender; undergraduate student; Administrative Supplement; Adult; Age; Aging; Automobile Driving; Award; Biological Markers; Cognition; Cognitive aging; Collection; Cross-Sectional Studies; Data; Data Collection; Distress; Educational workshop; Elderly; Equity; Funding; Future; Gender; Goals; Health; Health Disparities Research; Health Professional; Immune; Impaired cognition; Inflammation; Infrastructure; Investments; Lesbian Gay Bisexual; Life Experience; Measures; Mentors; Mentorship; Outcome; Parents; Pathway interactions; Patient Self-Report; Persons; Policies; Population; Postdoctoral Fellow; Psyche structure; Reporting; Research; Research Personnel; Sample Size; Sampling; Sex Orientation; Sexual and Gender Minorities; Sleep disturbances; Social Network; Social Policies; Spouses; Surveys; Training; United States National Institutes of Health; Universities; Variant; Work; cisgender; cognitive ability; cognitive function; cognitive testing; diversity and inclusion; experience; gender diversity; gender minority group; gender minority health disparity; graduate student; improved; member; minority stress; research study; training opportunity; transgender; undergraduate student

PROJECT SUMMARY No changes being proposed. INTRODUCTION This application is for an Administrative Supplement for Research on Sexual and Gender Minority (SGM) Populations (NOT-OD-22-032) to the parent award, ““Effects of Social Networks and Policy Context on Health among Older Sexual and Gender Minorities in the US South,” (R01AG063771). This application proposes to extend the parent award’s existing data collection among a panel of older sexual and gender minority (SGM) adults to include new objective measures of cognitive functioning. The parent award already includes self-reported cognitive functioning and analyses of cognition-related outcomes are within the scope of the parent award. As such, this proposal seeks to extend the range of SGM-related data and research questions on health and aging through the expansion of measures that are not available in this population. As we note in the strategy, there are currently no studies that directly measure cognitive functioning in self-identified SGM older adults regardless of relationship status and only one cross-sectional study has tested cognitive abilities across gender and sexual orientation in a sample inclusive of older adults (age 20-65).1 Very little work on self-reported cognitive aging in SGM populations is able to disaggregate the experiences and outcomes of SGM people by identity or other exposures (e.g., negative life experiences) due to small sample sizes. Several recent reports, including the 2023 Federal Evidence Agenda on LGBTQI+ Equity, highlight the lack of data on SGM populations that can be disaggregated to consider within-group variation in outcomes and mechanisms.2 The collection of new objective measures of cognitive functioning alongside the already-robust survey and biomarker infrastructure of the Vanderbilt University Social Networks, Aging, and Policy Study (VUSNAPS) will address both concerns by directly measuring cognitive functioning in a SGM sample that includes partnered and unpartnered older adults that is large enough to detect differences among cisgender and transgender/gender diverse SGM people, and among gay/lesbian and bisexual people. Additionally, these collection of cognitive functioning measures would contribute to new research on key questions that members of the VUSNAPS research network motivated to pursue, including: 1. Do SGM and nonSGM older adults differ in cognitive functioning and cognition trajectories in later life? 2. Are there within-group differences in cognitive functioning and cognition trajectories among the SGM population? 3. Are these differences attributable to minority stress exposures via inflammation, immune dysregulation, mental distress, and sleep disruption pathways? 4. Are the needs of SGM older adults experiencing cognitive decline different for those with and without partners/spouses and kin ties? Although no funds are specifically requested for training on this supplement, training and mentorship of DEIA trainees continues to be a primary goal of the VUSNAPS. The project has made significant investments in the training of diverse future health professionals, including 4 postdoctoral trainees, 3 graduate students, and 15 undergraduate students. We have completed a Diversity Supplement (R01AG063771-02S1) and have an active a Diversity Mentoring Supplement (R01AG063771-04S2) that aims to expand training opportunities in SGM health disparities by providing a two-day workshop to 25 junior, postdoc, and graduate researchers SGM aging and use of biomarkers in health disparities research. Our work has also generated multiple new training applications, including an R36 (Tran), a K01 (Barbee), and two LRP applications (Lampe and Barbee). Together, the activities we outline in this application will substantially improve the quality of date available on cognitive aging among SGM populations, extend the impact of NIH investments in the parent award, improve diversity and inclusion of SGM people in aging research, provide new opportunities for training SGM health disparities researchers, and contribute to new field-driving research on SGM cognitive aging.

项目摘要 没有提出任何变化。 介绍 该申请是为性和性别少数族裔研究的行政补充（SGM） 父母奖的人群（非OD-22-032），“社交网络和政策环境对健康的影响 在美国南部的年龄较大和性别少数群体中，”（R01AG063771）。 该申请提案将父母奖的现有数据收集扩展到一组较旧的性行为中 和性别少数族裔（SGM）成年人包括对认知功能的新客观测量。父母 奖项已经包括自我报告的认知功能和与认知相关结果的分析 在父母奖的范围内。 因此，该提案旨在扩大与SGM相关数据的范围和有关健康的研究问题 并通过扩大该人群中无法获得的措施而衰老。正如我们在 策略，目前尚无直接测量自我识别的认知功能的研究 SGM老年人不管关系状况如何，只有一项横断面研究测试了认知 包括老年人的样本中性别和性取向的能力（20-65岁）。1 很少的工作 关于SGM人群中自我报告的认知衰老，可以分解经验和结果 由于样本量较小，SGM人通过身份或其他暴露（例如，负面的生活经历）。一些 最近的报告，包括2023年的联邦证据议程，关于LGBTQI+权益，强调了缺乏有关的数据 可以分开考虑成果和机制内部变化的SGM种群。2 在本来已经有活跃的调查以及 范德比尔特大学社交网络，老龄化和政策研究（VUSNAPS）的生物标志物基础设施将 通过直接测量包括合作的SGM样本中的认知功能来解决这两种问题 并且没有十足的老年人，足够大，可以检测到Cisgender和 跨性别/性别多样化的SGM人，以及男同性恋和双性恋者。 此外，这些认知功能措施的收集将有助于关键的新研究 VUSNAPS研究网络成员融合购买的问题，包括： 1。稍后在认知功能和认知轨迹上不同 生活？ 2。在认知功能和认知轨迹上存在组内差异 SGM人口？ 3。这些差异是否可归因于通过注射，免疫的少数压力暴露 失调，精神困扰和睡眠中断途径？ 4。是SGM老年人的需求，患有和 没有伴侣/配偶和亲属关系？ 尽管没有专门要求对DEIA的补充，培训和精神制的资金进行培训 学员继续是Vusnaps的主要目标。该项目已在 培训潜水员未来的卫生专业人员，包括4位博士后学员，3名研究生和15名 本科生。我们已经完成了多样性补充（R01AG063771-02S1），并有一个 积极的多样性指导补充剂（R01AG063771-04S2）旨在扩大培训机会 SGM健康分布通过为25个初中，博士后和研究生研究人员提供为期两天的研讨会SGM 健康差异研究中生物标志物的衰老和使用。我们的工作也产生了多次新培训 应用程序，包括R36（Tran），K01（Barbee）和两个LRP应用程序（Lampe和Barbee）。 我们共同概述了本申请中的活动将大大提高可用日期的质量 SGM人群中认知老化，扩大NIH投资对父母奖的影响，改善 SGM人员在老龄化研究中的多样性和包容，为培训SGM Health提供了新的机会 差异研究人员，并为SGM认知衰老的新现场驾驶研究做出了贡献。