Frontiers in Cancer Research

癌症研究前沿

基本信息

批准号：
9753297
负责人：
Jeanne Ting Chowning
金额：
$ 26.93万
依托单位：
FRED HUTCHINSON CANCER RESEARCH CENTER
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-01 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9753297
关键词：
Address Bioethics Biological Biological Sciences Biomedical Engineering Biomedical Research Bone Marrow Transplantation CRISPR/Cas technology Career Choice Cessation of life Clinical Clinical Research Clinical Trials Communities Companions Development Discipline Disease Education Educational Curriculum Educational process of instructing Educational workshop Engineering Ethical Issues Ethics Fostering Fred Hutchinson Cancer Research Center Funding Genetic Engineering Goals Health Resources High School Student Human Immunotherapy International Knowledge Laboratories Learning Malignant Neoplasms Medical Research Mentors Modeling Molecular and Cellular Biology NCI Center for Cancer Research National Institute of General Medical Sciences Next Generation Science Standards Plasmids Program Development Proteins Randomized Controlled Trials Research Research Personnel Resources Role School Teachers Schools Science Scientist Secondary Schools Students Teacher Professional Development Training Translating Underrepresented Students Underserved Population United States National Institutes of Health Viola Visit Washington Work Youth anti-cancer anticancer research cancer immunotherapy cancer therapy career curriculum development design experience follow-up frontier gene therapy clinical trial interest learning materials lens novel strategies outreach program pedagogy precision genetics programs science education science teacher skills social student training teacher

项目摘要

PROJECT SUMMARY/ABSTRACT Frontiers in Cancer Research (“Frontiers”) is presented by the Science Education Partnership (SEP) at Fred Hutchinson Cancer Research Center (“Fred Hutch”). The Frontiers program is designed to meet two goals of the National Institutes of Health (NIH) and National Institute of General Medical Sciences (NIGMS): to increase the STEM content knowledge and pedagogical skills of teachers and to engage students, especially those from underserved populations, in basic and clinical medical research. Overall, Frontiers aims to increase public understanding of basic molecular and cellular biology, how this knowledge informs research questions, and how clinical research translates into cancer therapies and cures. More specifically, Frontiers focuses on exciting new NIH-funded research at Fred Hutch, such as immunotherapy, that promises to fundamentally change cancer treatment. The program will also explore the ethical implications of cancer research-related topics. Another goal is to introduce students, particularly those from backgrounds underrepresented in the biomedical sciences, to career possibilities in research. 1) Frontiers will engage secondary school students in basic molecular/cellular biology and cutting-edge cancer research by creating, piloting, and disseminating two Next Generation Science Standards (NGSS)-aligned cancer-focused curricular units (Project Violet: Anti-Cancer Molecules, Cancer Immunotherapy) and three different types of hands-on scientific kits (Protein Modeling and Cancer Treatment, Bioengineering Plasmid Design, and CRISPR/Cas9). The units, which will consist of 5-7 lessons to span 2-3 weeks, will also help students examine ethical issues related to genetic engineering, gene therapy, and clinical trials. We will use small randomized controlled trials to evaluate the efficacy of the developed curricular materials. 2) Frontiers will enhance the ability of secondary school life science teachers to teach fundamental biological principles and practices through the lens of cancer research by providing 20 teachers annually (Y2-Y5) with a 3-week summer professional development program that includes a mentored research experience, and 7 day- long sessions throughout the school year. 3) Frontiers aims to inspire secondary school students from underrepresented communities to pursue biomedical and clinical research careers. Our introductory school-year outreach program will bring 270 students annually to Fred Hutch to meet scientists and participate in Frontiers lessons held in dedicated Fred Hutch student training labs. We will also create and implement a model for scientists at Fred Hutch to visit classrooms to assist teachers with lessons and share their career paths with students.

项目概要/摘要癌症研究前沿（“前沿”）由弗雷德里克大学科学教育合作伙伴关系 (SEP) 提出哈钦森癌症研究中心（“Fred Hutch”）的前沿计划旨在实现以下两个目标：美国国立卫生研究院 (NIH) 和国立普通医学科学研究所 (NIGMS)：增加教师的 STEM 内容知识和教学技能，并吸引学生，特别是来自不同国家的学生总体而言，Frontiers 的目标是增加公众在基础和临床医学研究中服务不足的人群。了解基本分子和细胞生物学，这些知识如何指导研究问题，以及更具体地说，Frontiers 专注于临床研究如何转化为癌症疗法和治愈方法。 Fred Hutch 的 NIH 资助的令人兴奋的新研究，例如免疫疗法，有望从根本上该计划还将探讨癌症研究相关的伦理影响。另一个目标是介绍学生，特别是那些来自在该领域代表性不足的背景的学生。生物医学科学，研究职业的可能性。 1) Frontiers 将让中学生学习基础分子/细胞生物学和前沿癌症通过创建、试点和传播两个符合下一代科学标准 (NGSS) 的研究以癌症为重点的课程单元（紫罗兰计划：抗癌分子、癌症免疫疗法）和三个不同类型的实践科学套件（蛋白质建模和癌症治疗、生物工程质粒这些单元将包含 5-7 节课程，持续 2-3 周，也将有所帮助。学生们研究与基因工程、基因治疗和临床试验相关的伦理问题。小型随机对照试验来评估所开发课程材料的功效。 2) Frontiers将提升中学生命科学教师教授基础生物学的能力每年为 20 名教师（Y2-Y5）提供癌症研究视角的原则和实践为期 3 周的夏季专业发展计划，包括指导研究经验和 7 天的整个学年的长时间课程。 3) Frontiers 旨在激励代表性不足社区的中学生追求我们的入门学年推广计划将带来 270 名生物医学和临床研究职业。学生每年都会到 Fred Hutch 会见科学家并参加专门在 Fred Hutch 举办的前沿课程我们还将创建并实施一个模型，供 Fred Hutch 的科学家参观。课堂协助教师上课并与学生分享他们的职业道路。