University of Louisville Cagewash Modernization

路易斯维尔大学笼洗现代化

• 批准号: 10736321
• 负责人: Leslie C. Sherwood
• 金额: $ 30.64万
• 依托单位: UNIVERSITY OF LOUISVILLE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10736321
• 关键词: 20 year old; Alcohols; Allergens; Animal Experimentation; Animals; Appalachian Region; Area; Award; Basic Science; Cardiovascular system; Cell Nucleus; Censuses; Centers of Research Excellence; Development; Electronic cigarette; Employment; Equipment; Friends; Funding; Grant; Growth; Health; Health Sciences; Inflammation; Inhalation; Institution; Kentucky; Maintenance; Microcomputers; Mission; Modeling; Modernization; National Institute of General Medical Sciences; Occupational Health; Phase; Population; Research; Research Personnel; Rodent; Science; Strategic Planning; Superfund; Technology; Toxicology; Toxin; United States National Institutes of Health; Universities; animal facility; cancer immunotherapy; cardiometabolism; cigarette smoke; cost; diversity and inclusion; equity, diversity, and inclusion; ergonomics; ethnic minority; hazard; improved; innovation; medically underserved; microbiome research; programs; repaired; tumor immunology; undergraduate student; underserved community

ABSTRACT The University of Louisville (UofL) is an Institution of Emerging Excellence (IEE) and one of 23 states designated by the National Institutes of Health (NIH) as an Institutional Development Award (IDeA) state, serving the research needs of medically underserved communities. As part of the IDeA state program, UofL is the recipient of four NIH funded Centers of Biomedical Research Excellence (COBRE) projects to target local and regional health crises in Kentucky and Appalachia. These include centers in 1) Center for Cardiometabolic Science, 2) Microbiomics and Inflammation, 3) Hepatobiology and Toxicology, and 4) Cancer Immunology and Immunotherapy. UofL is also the recipient of NIH funding for the Alcohol Center and the Envirome Institute Superfund Research Center, which studies the effects of cigarette smoke, e- cigarettes and other inhaled toxins on the cardiovascular system. UofL is requesting $306,360.00 for a modern, innovative, eco-friendly tunnel washer in the centrally located A- Tower Research Building Cagewash Facility. The A-Tower is adjacent to six research buildings that comprise the nucleus of the Health Sciences Campus (HSC), and serves as the primary cage wash facility for all rodent species on the HSC and the undergraduate Belknap campus. It also provides essential support for large animal cage washing. The current tunnel washer is over 20 years old, and is not ergonomically or eco-friendly. Routine maintenance and repair are frequent and costly. The Better Built Tunnel Washer, Model T236, represents a major innovative upgrade in cage wash equipment that is eco-friendly, integrative, and utilizes microcomputer technology. The new tunnel washer will increase our current cage wash throughput capacity by 25% for rodent caging and large animal caging accessories, to accommodate our growing rodent and large animal populations. The new cage washer will provide essential support for the four NIH funded COBRE grants, the Envirome Institute Superfund, and 64 investigators in 24 departments across the HSC and Belknap campus. A broad, diverse range of investigators and their research efforts in both biomedical and basic sciences will benefit from this equipment in this shared-use facility. This aligns with the principal missions of the NIH-NIGMS. UofL echoes these missions, with the establishment of the Diversity, Equity and Inclusion Strategic Plan in 2017 and the HSC Office of Diversity and Inclusion, which is committed to expanding funding and employment of ethnic minorities.

抽象的 路易斯维尔大学（UOFL）是一个新兴卓越的机构（IEE），是23个 国立卫生研究院（NIH）指定为机构发展的国家 奖励（想法）国家，为医学服务不足的社区的研究需求服务。作为一部分 在Idea State计划中，UOFL是四个基金会资助的生物医学中心的接受者 卓越研究（COBRE）项目针对肯塔基州的地方和地区卫生危机 和阿巴拉契亚。其中包括1）心脏代谢科学中心，2） 微生物学和炎症，3）肝病学和毒理学，以及4）癌症免疫学 和免疫疗法。 UOFL也是酒精中心的NIH资金的接受者 Envirome Institute SuperFund Research Center，研究香烟烟的影响，E- 心血管系统上的香烟和其他吸入的毒素。 UOFL要求 $ 306,360.00用于现代，创新，环保的隧道洗衣机，位于中央 塔研究大楼的塞奇洗车设施。 A-Tower毗邻六座研究建筑 这包括健康科学校园（HSC）的核心，并作为主要 HSC和本科Belknap校园上所有啮齿动物物种的笼子清洗设施。它 还为大型动物笼洗涤提供了必不可少的支持。当前的隧道垫圈是 超过20年的历史，并且在人体工程学或环保上不友好。常规维护和维修是 频繁且昂贵。建造更好的隧道洗衣机T236代表了主要的创新 在环保，整合的笼子清洗设备中升级，并利用微型计算机 技术。新的隧道洗衣机将使我们当前的笼式洗涤吞吐量增加 25％用于啮齿动物笼和大型动物笼附件，以适应我们的生长 啮齿动物和大型动物种群。新的笼子洗衣机将为 NIH资助的毛绒赠款，环境学院超级基金和64名调查员在24个 HSC和Belknap校园的部门。广泛，多样化的调查员和 他们在生物医学和基础科学方面的研究工作将从该设备中受益 这种共享使用设施。这与NIH-Nigms的主要任务保持一致。 UOFL回声 这些任务，建立了多样性，公平和包容性战略计划 2017年和HSC多样性与包容办公室，致力于扩大资金 和少数民族的雇用。