CELL CULTURE CORE FACILITY

细胞培养核心设施

• 批准号: 7561431
• 负责人: William S Baldwin
• 金额: $ 11.53万
• 依托单位: UNIVERSITY OF TEXAS EL PASO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7561431
• 关键词: Carbon Dioxide; Cells; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Cultured Cells; Depth; Equipment; Eukaryotic Cell; Freezing; Funding; Genus Mycobacterium; Grant; Hepatitis B Virus; Immune; Immune response; Incubators; Infectious Agent; Institution; Investigation; Microscope; Mycobacterium tuberculosis; Physiological; Research; Research Infrastructure; Research Personnel; Resources; Source; Support of Research; United States National Institutes of Health; Virus; Water Supply; cold temperature; response; toxicant

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The ability to maintain mammalian and other eukaryotic cells in culture is an essential part of studies on cellular immune and physiological responses as well as investigations into infectious agents such as viruses and Mycobacterium tuberculosis. Specilized culturing equipment and incubators are required to maintain such cultures. This proposal provides for an investigator accessible, managed core facility to provide equipment and technical support for Border Biomedical Recearch Center researchers whose projects rely on cell culture. Equipment infrastructure will include hiosafety cabinets, CO2 incubators, deep freeze and ultra low temperature storage facilities, inverted and compound microscopes, and ultrapure water supply. Such support is and will be essential for the support of research into the effects of toxicants on cells, cellular immune responses, and studies on HBV and mycobacteria.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 维持哺乳动物和其他真核细胞培养的能力是细胞免疫和生理反应研究以及病毒和结核分枝杆菌等传染源研究的重要组成部分。 需要专门的培养设备和培养箱来维持这种培养。 该提案提供了一个研究人员可访问、受管理的核心设施，为边境生物医学研究中心的研究人员提供设备和技术支持，这些研究人员的项目依赖于细胞培养。 设备基础设施将包括安全柜、二氧化碳培养箱、深度冷冻和超低温储存设施、倒置和复合显微镜以及超纯水供应。 这种支持对于支持毒物对细胞影响的研究、细胞免疫反应以及乙型肝炎病毒和分枝杆菌的研究来说是至关重要的。