University of Iowa Institutional Training Program in Oral Health Research

爱荷华大学口腔健康研究机构培训计划

基本信息

批准号：
10710934
负责人：
STEVEN M. LEVY
金额：
$ 48.04万
依托单位：
UNIVERSITY OF IOWA
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-07-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10710934
关键词：
Academia Address Advisory Committees Area Behavioral Sciences Big Data Biocompatible Materials Biomedical Engineering Biometry Clinical Critiques Dental Dental caries Dentistry Dentists Discipline Doctor of Philosophy Education Educational process of instructing Educational workshop Environment Epidemiology Faculty Fellowship Funding Genetic Grant Health Policy Health Sciences Immunology Inflammation Institution Interdisciplinary Study International Iowa K-Series Research Career Programs Leadership Mentors Microbiology Odontogenesis Oral Oral health Outcome Postdoctoral Fellow Productivity Public Health Research Research Personnel Research Training Science Series Tissue Engineering Training Training Programs Translational Research Universities Update Writing career clinical investigation cohort college craniofacial experience faculty mentor improved leadership development malignant mouth neoplasm microbiome oral biology pre-doctoral programs recruit research facility skills stem cells success translational scientist

项目摘要

Project Summary This competitive renewal application proposes to continue our program to provide comprehensive, integrated training in dental and craniofacial research at the University of Iowa (UI) to a cohort of basic, clinical, and translational researchers and dental scholars. It will provide dentists and non-dentists with a comprehensive skillset to meet the challenges of oral health research in academia for the 21st century. Outstanding interdisciplinary didactic training and rigorous research mentoring will emphasize ongoing review and critique. The proposed program builds on 37 years of research training success, with several major enhancements listed briefly below. The program addresses 7 major research training areas: 1) Craniofacial, Oral Biology, Genetics, and Dental Development; 2) Bioengineering, Tissue Engineering, Stem Cells, Biomaterials, and Materials; 3) Immunology, Inflammation, Microbiology, Caries, and Microbiome; 4) Oral Cancer; 5) Public Health, Epidemiology, and Behavioral Sciences; 6) Oral Health Policy; and 7) Clinical, Translational, and Big Data Research, reflecting the strengths of the College of Dentistry, UI health science colleges, and collaborative institutes and centers. Trainees in the proposed program will pursue a PhD in Oral Science (or in one of the 13 other affiliated PhD programs) or a post-doctoral fellowship. In addition, trainees now will be able to obtain a Graduate Certificate in College Teaching, Biostatistics, or Translational and Clinical Investigation or an MS in Dental Public Health. The T90 will support 4 non-dentist predocs and 2 dentists for the PhD (3 years each) and 1 non-dentist postdoc (2 years). The R90 component reflects the importance international dentists have in U.S. oral health research programs and will support 2 dentists for the PhD (3 years each). A group of 28 experienced program faculty from a variety of disciplines is available to mentor trainees. The success of our program over the past 4+ years is seen in 5 trainees receiving F- or K-awards since 2019 and trainees’ successful career placement. To build on this success, we propose several improvements/new major components of this Oral Health Research Institutional Training Program. The successful Grant-Writing Workshop Series has been updated and enhanced. Additionally, we propose several new programs, including ones in Research Rigor, Research Leadership Development, and Interdisciplinary Faculty Mentoring. Training will be supervised by the experienced Director and Associate Director and implemented in concert with a Faculty Leadership Team. Several committees will support the program: internal and external advisory committees, importantly a Committee on Recruitment and Diversity, and other component-specific committees. In summary, the program brings together productive, well-funded mentors with pre- and post-doctoral trainees in an environment with a strong institutional commitment, outstanding interdisciplinary research training in relevant disciplines, and excellent educational and research facilities. The outcome will be a cadre of oral health researchers ready to function at the cutting edge of their disciplines.

项目概要这项具有竞争力的续订申请旨在继续我们的计划，以提供全面、综合的服务在爱荷华大学 (UI) 接受牙科和颅面研究培训，培训一批基础、临床和它将为牙医和非牙医提供一个翻译研究人员和牙科学者。应对 21 世纪学术界口腔健康研究挑战的综合技能。出色的跨学科教学培训和严格的研究指导将强调持续的审查拟议的计划建立在 37 年研究培训成功的基础上，有几个主要内容。下面简要列出了该计划的增强功能，涉及 7 个主要研究培训领域：1) 颅面、口腔生物学、遗传学和牙齿发育；2) 生物工程、组织工程、干细胞、生物材料和材料；3) 免疫学、炎症、微生物学、龋齿和微生物组；癌症；5) 公共卫生、流行病学和行为科学；6) 口腔健康政策；7) 临床、转化和大数据研究，体现了爱荷华大学牙科学院健康科学的优势拟议项目的学员将攻读口语博士学位。科学（或其他 13 个附属博士项目之一）或博士后奖学金此外，还包括实习生。现在将能够获得大学教学、生物统计学或转化和临床研究生证书 T90 将为 4 名非牙医预科医师和 2 名牙医提供牙科公共卫生调查或硕士学位。博士（各 3 年）和 1 个非牙医博士后（2 年）。国际牙医在美国有口腔健康研究项目，并将支持 2 名牙医攻读博士学位（3 每学年），由 28 名来自不同学科的经验丰富的项目教师组成。过去 4 年多来，我们的计划取得了成功，有 5 名学员获得了 F 或 K 奖。自 2019 年以来以及学员成功的职业安置在此基础上，我们提出了几项建议。该口腔健康研究机构培训计划的改进/新的主要组成部分。此外，我们还对成功的资助写作研讨会系列进行了更新和增强。新项目，包括研究严谨性、研究领导力发展和跨学科项目教师培训将由经验丰富的主任和副主任监督。与教师领导团队合作实施，几个委员会将支持该计划：内部和外部咨询委员会，重要的是招聘和多元化委员会，以及其他总之，该计划汇集了富有成效、资金充足的导师。在具有强有力的机构承诺的环境中与博士前和博士后培训生一起，相关学科的跨学科研究训练，以及优良的教育和研究设施。其结果将是一批口腔健康研究人员准备好在各自学科的前沿发挥作用。

项目成果

期刊论文数量（11）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Amine modification of nonporous silica nanoparticles reduces inflammatory response following intratracheal instillation in murine lungs.

DOI：
10.1016/j.toxlet.2015.11.006
发表时间：
2016-01-22
期刊：
Toxicology letters
影响因子：
3.5
作者：
Morris AS;Adamcakova-Dodd A;Lehman SE;Wongrakpanich A;Thorne PS;Larsen SC;Salem AK
通讯作者：
Salem AK

Choline and geranic acid (CAGE) ionic liquids inhibit both elastase activity and growth of oral bacteria.

胆碱和香叶酸 (CAGE) 离子液体可抑制弹性蛋白酶活性和口腔细菌的生长。

DOI：
10.1002/jbm.a.37485
发表时间：
2023
期刊：
Journal of biomedical materials research. Part A
影响因子：
0
作者：
Laird,NoahZ;Phruttiwanichakun,Pornpoj;Zhu,Min;Banas,JeffreyA;Elangovan,Satheesh;Salem,AliasgerK
通讯作者：
Salem,AliasgerK

Parents and Provider Perspectives on the Return of Genomic Findings for Cleft Families in Africa.

父母和提供者对非洲裂隙家庭基因组发现返回的看法。

DOI：
10.1080/23294515.2024.2302993
发表时间：
2024
期刊：
AJOB empirical bioethics
影响因子：
0
作者：
Oladayo,AbimbolaM;Prochaska,Sydney;Busch,Tamara;Adeyemo,WasiuL;Gowans,LordJJ;Eshete,Mekonen;Awotoye,Waheed;Sule,Veronica;Alade,Azeez;Adeyemo,AdebowaleA;Mossey,PeterA;Prince,Anya;Murray,JeffreyC;Butali,Azeez
通讯作者：
Butali,Azeez

Fetal and neonatal maxillary ontogeny in extant humans and the utility of prenatal maxillary morphology in predicting ancestral affiliation.

现存人类的胎儿和新生儿上颌骨个体发育以及产前上颌骨形态在预测祖先关系中的效用。