Secondary Analyses of Adolescent Caries, Including Fluoride, Diet & Other Factors

青少年龋齿的二次分析，包括氟化物、饮食

• 批准号: 8612838
• 负责人: STEVEN M. LEVY
• 金额: $ 15.1万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-10 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8612838
• 关键词: Address; Adolescence; Adolescent; Age; Applications Grants; Attention; Beverages; Birth; Caries prevention; Child; Childhood; Cohort Studies; Complex; Consumption; Data; Data Analyses; Demographic Factors; Dental Hygiene; Dental caries; Development; Diet; Dietary Factors; Dietary Practices; Disease; Etiology; Exposure to; Fluorides; Goals; Health behavior; Incidence; Individual; Intake; Iowa; Literature; Oral health; Outcome; Pattern; Period Analysis; Prevalence; Prevention program; Public Health; Public Policy; Recruitment Activity; Relative (related person); Research; Risk; Risk Factors; Role; Sales; Secondary Schools; Time; Work; age group; cohort; demographics; early childhood; experience; improved; permanent tooth; prevent; programs; public health relevance; sugar; theories

A century after theories identified the prominent roles of sugars in dental caries etiology and the discovery of the beneficial effects of fluorides, caries remains a highly prevalent disease throughout childhood, including adolescence. Adolescents' greater independence and frequent exposure to sugared beverages (e.g., soda pop) appear to place them at greater risk than at younger ages. However, these caries incidence patterns and relationships with risk factors are poorly understood because there are few studies of caries incidence or risk factors among adolescent subjects. Since 1991, using a cohort recruited at birth, the ongoing Iowa Fluoride Study (IFS) has comprehensively assessed the relationships between dietary data and fluoride exposures and dental caries in individuals at ages 5, 9, and 13. As caries continues to be a significant disease in adolescents, the proposed study provides a unique opportunity to assess the effects of socio-demographic, dietary, fluoride, and other factors on the incidence of dental caries during adolescence from age 13 to 17 years in our cohort. The main objectives of this proposal are to 1) conduct detailed secondary analyses of patterns of dental caries of the permanent dentition at age 17 and caries incidence from 13 to 17, and 2) comprehensively examine the relationships among dental caries incidence from age 13 to 17 (and age 17 prevalence) and dietary, fluoride, prior caries experience, and socio-demographic factors. Multivariable analyses will assess the relationships between and interactions among caries outcomes (incidence/increments and prevalence/counts) and longitudinally-collected data on various dietary patterns, oral health behaviors, fluoride exposures, previous caries experience, socio-demographics, and other factors. We will then assess the consistency of our findings concerning caries risk factors for ages 13 to 17 with those from analyses of caries risk factors during earlier periods from ages 5 to 9 and 9 to 13. As studies involving recruitment and successful retention of a cohort from birth are extremely rare, the Iowa Fluoride Study offers a unique opportunity to study these relationships in unprecedented detail, enhancing our ability to develop effective adolescent caries prevention programs.

在理论确定糖在龋齿病因和发现中的重要作用的一个世纪之后 在氟化物的有益作用中，龋齿在整个儿童期仍然是一种高度普遍的疾病，包括 青春期。青少年更大的独立性和频繁接触糖饮料（例如，苏打水 POP）似乎使它们面临着比年轻年龄更大的风险。但是，这些龋齿发生率模式和 与危险因素的关系知之甚少，因为龋齿发生率或风险的研究很少 青少年受试者的因素。自1991年以来，使用出生时招募的队列，即持续的爱荷华州氟化物 研究（IFS）已全面评估了饮食数据与氟化物暴露与氟化物之间的关系 5、9和13岁的个体的龋齿。随着龋齿在青少年中仍然是一种重要的疾病， 拟议的研究为评估社会人口统计学，饮食，氟化物的影响提供了独特的机会 以及我们队列中从13岁到17岁的青春期龋齿发生率的其他因素。 该提案的主要目标是1）进行牙科模式的详细次要分析 17岁时永久牙列的龋齿，龋齿发生率从13到17，2）全面 检查从13岁到17岁（和17岁患病率）和 饮食，氟化物，先前的龋齿经验和社会人口统计学因素。多变量分析将评估 龋齿结果之间的关系和相互作用（发病率/增量和 患病率/计数）和有关各种饮食模式，口腔健康行为，氟化物的纵向收集数据 暴露，以前的龋齿经验，社会人口统计学和其他因素。然后，我们将评估 我们关于13至17岁的龋齿危险因素的发现的一致性以及龋齿分析的一致性 从5到9至9至13岁的早期时期的危险因素。作为涉及招聘和成功的研究 从出生开始的队列保留极为罕见，爱荷华州氟化物研究为学习提供了独特的机会 这些关系以前所未有的细节，增强了我们发展有效的青少年龋齿的能力 预防计划。