Music Video and Adolescent Resilience During Transplant

移植期间的音乐视频和青少年的复原力

• 批准号: 7092075
• 负责人: JOAN Ellen HAASE
• 金额: $ 46.77万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-07 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7092075
• 关键词: adolescence (12-20); alternative medicine; behavioral /social science research tag; clinical research; clinical trials; coping; family structure /dynamics; human subject; human therapy evaluation; injury /disease stressor; music therapy; nursing research; patient oriented research; postoperative state; psychological aspect of cancer; quality of life; self concept; social support network; statistics /biometry; stem cell transplantation; videotape /videodisc; young adult human (21-34)

DESCRIPTION (provided by applicant): Statement of Problem: Stem cell transplant (SCT), the curative therapy of choice for many malignancies that require high-dose radiation or chemotherapy, is an intensive, multi-phase procedure with many risks, including death, Recent studies suggest that SCT is a particularly stressful procedure for adolescents and young adults (AYA) and may result in significant short-and long-term decrements in quality of life. Broad Objective: To develop and test the efficacy of a therapeutic music video (TMV) intervention aimed at increasing resilience and quality of life of AYA undergoing SCT. Specific Aims: To determine whether AYA assigned to the TMV intervention, compared to a low dose control group, experience: 1) reduced illness-related distress; 2) improved family environment; 3) increased perceived social support; 4) improved coping; 5) greater derived meaning; 6) increased resilience and quality of life. Secondary aims include qualitatively examining the self-reported benefits of the TMV intervention and the low-dose books-on-tape intervention for AYA and their family caregivers. Design and Method: Randomized, controlled trial methods will be used for this multi-site study. Approximately 130 AYA between 11 and 24 years of age undergoing SCT for cancer will be assigned to either the TMV intervention group or to a low dose control group. Intervention participants will be guided by a board certified music therapist to develop a music video based on their experiences with cancer over the course of 6 sessions. Low dose control participants will take part in a 6 session books-on-tape program. Outcomes data will be collected at multiple time points during the patient's hospitalization and at 100 days post-transplant using self-report inventories assessing the constructs described in the Specific Aims. Group differences will be examined using a linear mixed models approach and qualitative data will be analyzed using an adaptation of Colaizzi's method of phenomenological analysis.

描述（由申请人提供）：问题陈述：干细胞移植（SCT）是许多需要高剂量放疗或化疗的恶性肿瘤的首选治疗方法，是一种密集的多阶段手术，存在许多风险，包括死亡、最近的研究表明，SCT 对青少年和年轻人 (AYA) 来说是一种压力特别大的手术，可能会导致生活质量显着的短期和长期下降。广泛目标：开发和测试治疗性音乐视频 (TMV) 干预的功效，旨在提高接受 SCT 的 AYA 的恢复能力和生活质量。具体目标：为了确定 AYA 是否分配到 TMV 干预组，与低剂量对照组相比，是否体验到：1）减少了疾病相关的痛苦； 2）改善家庭环境； 3）增加感知的社会支持； 4）改善应对方式； 5）更大的衍生意义； 6）提高适应力和生活质量。次要目标包括定性检查 AYA 及其家庭护理人员自我报告的 TMV 干预和低剂量磁带书干预的益处。设计和方法：本次多中心研究将采用随机对照试验方法。大约 130 名 11 至 24 岁之间因癌症接受 SCT 的 AYA 将被分配到 TMV 干预组或低剂量对照组。干预参与者将在经过委员会认证的音乐治疗师的指导下，根据他们在 6 个疗程中的癌症经历制作音乐视频。低剂量控制参与者将参加为期 6 节的磁带书籍计划。将使用自我报告清单在患者住院期间和移植后 100 天的多个时间点收集结果数据，评估具体目标中描述的结构。将使用线性混合模型方法检查组间差异，并使用改进的 Colaizzi 现象学分析方法对定性数据进行分析。