RESILIENCE & QUALITY OF LIFE IN ADOLESCENTS WITH CANCER

弹力

• 批准号: 2771830
• 负责人: JOAN Ellen HAASE
• 金额: $ 7.64万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-01 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2771830
• 关键词: adolescence (12-20); behavioral /social science research tag; child (0-11); clinical research; family structure /dynamics; human subject; human therapy evaluation; longitudinal human study; pediatric neoplasm /cancer; psychological adaptation; psychological aspect of cancer; psychological models; psychometrics; quality of life; self concept; social psychology; social support network

DESCRIPTION: (Adapted from investigator's abstract) Statistics for childhood cancer demonstrate greatly improved survival rates over the last twenty years in the United States. Depending on the type of cancer, 58-88% of children and adolescents will be long-term, disease free survivors. While such statistics are encouraging, the nature and course of many cancers has changed from an inevitably fatal illness to a chronic illness that continues to carry the potential to threaten life. The American Cancer Society had identified adolescent cancer care, including psychosocial care, as a research priority. Yet, surprisingly few data-based studies have been reported on psychosocial adjustment of adolescents with cancer (AWC). In addition, systematically planned psychosocial intervention studies with AWC are rare, even though such interventions, tested over the last 2 decades in adults with cancer, show promising results. With over 200,000 childhood cancer survivors and the numbers projected to be 1 in 250 by the year 2000, it is imperative that adjustment issues for adolescents with cancer be addressed. The purposes of this study are to: 1) examine, longitudinally, the nature and patterns of change in resilience and quality of life through analysis of the Adolescent Resilience Model (ARM) in adolescents with cancer; and, 2) evaluate the extent to which patterns of resilience and quality of life change as a result of a family and adolescent network (FAN) intervention aimed at enhancing resilience and quality of life through individual, family and social protective factors in the ARM. The study design contains two components. To answer questions about relationships and causality among individual, family and social protective factors, illness-related and individual risk factors, and resilience and quality of life among adolescents with cancer, 11-19 year of age, a prospective longitudinal descriptive design will be used. The adolescents will be followed from diagnosis through the first of living with cancer. In the last 2 1/2 years of the project, after refinement and pilot work is done on the FAN intervention, a longitudinal experimental design w ill be implemented to evaluate changes that occur in the factors in the ARM as a result of a Family and Adolescent Network (FAN) intervention that is targeted to enhance individual, family, and social protective factors in the model and minimize illness- related and individual risk factors. The proposed total sample size is 243. Analysis of study aims will be accomplished through: 1) growth curve analysis to evaluate initial state, rate of change and stability; 2) common factor modeling of growth curve parameters; and 3) structural modeling of change factors over time and as a result of the intervention.

描述：（改编自研究者的摘要）统计数据 儿童癌症的生存率比过去大大提高 来美国二十年。 根据癌症类型，58-88% 的儿童和青少年将成为长期、无病的幸存者。 虽然这些统计数据令人鼓舞，但许多癌症的性质和病程 从不可避免的致命疾病变成了慢性疾病 继续具有威胁生命的潜力。 美国癌症 社会已经确定了青少年癌症护理，包括社会心理护理、 作为研究重点。 然而，令人惊讶的是，基于数据的研究却很少 报告了患有癌症的青少年的心理社会调整（AWC）。 在 此外，与 AWC 一起进行系统规划的社会心理干预研究 尽管此类干预措施在过去 20 年中经过了测试，但这种情况很少见 患有癌症的成年人显示出有希望的结果。 拥有超过20万童年 癌症幸存者，预计到 2000 年，这一数字将达到每 250 人中就有 1 人， 癌症青少年的调整问题势在必行 已解决。 本研究的目的是：1）纵向检查 复原力和生活质量变化的性质和模式 青少年复原力模型（ARM）分析 癌症; 2) 评估复原力和模式的程度 家庭和青少年网络 (FAN) 导致生活质量发生变化 旨在通过以下方式增强复原力和生活质量的干预措施 ARM 中的个人、家庭和社会保护因素。 研究 设计包含两个组成部分。 回答有关关系和关系的问题 个人、家庭和社会保护因素之间的因果关系， 疾病相关的和个人的风险因素，以及恢复力和质量 11-19 岁癌症青少年的生活，一项前瞻性研究 将使用纵向描述性设计。 青少年将是 从诊断到第一次患有癌症。 在 该项目的最后 2 1/2 年，在完成细化和试点工作后 FAN 干预，纵向实验设计将是 实施以评估 ARM 中因素发生的变化作为 家庭和青少年网络 (FAN) 干预的结果 旨在增强个人、家庭和社会的保护因素 建立模型并最大程度地减少与疾病相关的风险因素和个人风险因素。 这 拟议的总样本量为 243。研究目标分析将是 通过以下方式完成：1）生长曲线分析以评估初始状态， 变化率和稳定性； 2）生长曲线的公因子建模 参数; 3）随着时间的推移变化因素的结构建模 干预的结果。