Clinical Trials Network: New Mexico Node

临床试验网络：新墨西哥节点

• 批准号: 6795557
• 负责人: WILLIAM R. MILLER
• 金额: $ 155.55万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6795557
• 关键词: antipsychotic agents; behavior test; behavior therapy; behavioral /social science research tag; borderline personality disorder; clinical research; clinical trials; cocaine; combination therapy; comorbidity; cooperative study; drug /alcohol abstinence; drug abuse; drug abuse chemotherapy; drug abuse therapy; family therapy; human subject; human therapy evaluation; metabolism disorder chemotherapy; methadone; outcomes research; patient oriented research; psychological reinforcement; serotonin inhibitor; substance abuse related behavior; urinalysis

DESCRIPTION (provided by applicant): The University of New Mexico Center on Alcoholism, Substance Abuse, and Addictions (CASAA) submits a revised application to join the NIDA Clinical Trials Network as a Regional Research and Training Center and coordinate a New Mexico Node. CASAA and the collaborating Department of Psychiatry of UNM's School of Medicine have well -established infrastructure for behavioral and pharmacotherapy trials, and long experience with collaborative and multisite trials in the addiction field. Particular strengths that the proposed New Mexico Node team can bring to the CTN include: 1) expertise in "Stage III" research on dissemination and training of evidence-based treatments 2) a well -established track record of clinical trials for both behavioral and pharmacotherapies 3) a high concentration (70%) of minority patients in the affiliated CTP's, and substantial experience in research on cultural influences on and adaptations of drug abuse treatment 4) longstanding experience in the development and evaluation of innovative treatment methods for substance use disorders 5) substantial clinical and research experience with challenging populations including dual disorders, the homeless, and runaway adolescents 6) expertise in studying the influence of mutual help (e.g., 12-step) programs on treatment outcomes, and more generally in research on spirituality and addictions 7) geographic representation of the border Southwest To illustrate CTN-wide research that could be initiated from the New Mexico node, protocol concepts for three clinical trials are described, encompassing a behavioral intervention, a pharmacotherapy, and methods for disseminating an evidence-based treatment into clinical practice.

描述（由申请人提供）：新墨西哥大学酒精中毒，药物滥用和成瘾中心（CASAA）提交了修订的申请，将NIDA临床试验网络加入区域研究和培训中心，并协调新墨西哥州的节点。 CASAA和UNM医学学院精神病学系合作部门拥有良好的基础设施，用于行为和药物治疗试验，并在成瘾领域进行了长期的协作和多站点试验的经验。拟议的新墨西哥节点团队可以为CTN带来的特殊优势包括： 1）关于传播和培训循证治疗的“第三阶段”研究专业知识 2）行为和药物治疗的临床试验的完善记录 3）在CTP附属的少数族裔患者中，高浓度（70％），以及在文化影响和适应药物滥用治疗的研究方面的丰富经验 4）在开发和评估物质使用障碍的创新治疗方法方面的长期经验 5）在包括双重疾病，无家可归者和失控的青少年在内的具有挑战性人群的实质性临床和研究经验 6）研究相互帮助（例如，12步）计划对治疗结果的影响，更广泛地研究灵性和成瘾的研究 7）边界西南的地理代表 为了说明可以从新墨西哥节点开始的CTN范围内的研究，描述了三个临床试验的方案概念，包括行为干预，药物治疗以及将基于循证治疗传播到临床实践中的方法。