Clinical Trials Network: New Mexico Node

临床试验网络：新墨西哥节点

• 批准号: 6793944
• 负责人: WILLIAM R. MILLER
• 金额: $ 2.61万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6793944
• 关键词: antipsychotic agents; behavior test; behavior therapy; behavioral /social science research tag; borderline personality disorder; clinical research; clinical trials; cocaine; combination therapy; comorbidity; cooperative study; drug /alcohol abstinence; drug abuse; drug abuse chemotherapy; drug abuse therapy; family therapy; human subject; human therapy evaluation; metabolism disorder chemotherapy; methadone; outcomes research; patient oriented research; psychological reinforcement; serotonin inhibitor; substance abuse related behavior; urinalysis

DESCRIPTION (provided by applicant): The University of New Mexico Center on Alcoholism, Substance Abuse, and Addictions (CASAA) submits a revised application to join the NIDA Clinical Trials Network as a Regional Research and Training Center and coordinate a New Mexico Node. CASAA and the collaborating Department of Psychiatry of UNM's School of Medicine have well -established infrastructure for behavioral and pharmacotherapy trials, and long experience with collaborative and multisite trials in the addiction field. Particular strengths that the proposed New Mexico Node team can bring to the CTN include: 1) expertise in "Stage III" research on dissemination and training of evidence-based treatments 2) a well -established track record of clinical trials for both behavioral and pharmacotherapies 3) a high concentration (70%) of minority patients in the affiliated CTP's, and substantial experience in research on cultural influences on and adaptations of drug abuse treatment 4) longstanding experience in the development and evaluation of innovative treatment methods for substance use disorders 5) substantial clinical and research experience with challenging populations including dual disorders, the homeless, and runaway adolescents 6) expertise in studying the influence of mutual help (e.g., 12-step) programs on treatment outcomes, and more generally in research on spirituality and addictions 7) geographic representation of the border Southwest To illustrate CTN-wide research that could be initiated from the New Mexico node, protocol concepts for three clinical trials are described, encompassing a behavioral intervention, a pharmacotherapy, and methods for disseminating an evidence-based treatment into clinical practice.

描述（由申请人提供）：新墨西哥大学酗酒、药物滥用和成瘾中心 (CASAA) 提交了一份修订后的申请，以作为区域研究和培训中心加入 NIDA 临床试验网络并协调新墨西哥节点。 CASAA 和 UNM 医学院精神病学系拥有完善的行为和药物治疗试验基础设施，以及在成瘾领域合作和多中心试验的长期经验。拟议的新墨西哥节点团队可以为 CTN 带来的具体优势包括： 1) 循证治疗传播和培训“第三阶段”研究的专业知识 2) 行为疗法和药物疗法临床试验的良好记录 3) 附属 CTP 中少数民族患者高度集中（70%），并且在药物滥用治疗的文化影响和适应研究方面拥有丰富的经验 4) 在物质使用障碍创新治疗方法的开发和评估方面拥有长期经验 5) 在具有挑战性的人群（包括双重疾病、无家可归者和离家出走的青少年）方面拥有丰富的临床和研究经验 6) 研究互助（例如，12步）计划对治疗结果的影响的专业知识，更普遍的是在灵性和成瘾研究方面的专业知识 7）西南边境的地理代表性 为了说明可以从新墨西哥节点启动的 CTN 范围内的研究，描述了三个临床试验的方案概念，包括行为干预、药物治疗以及将循证治疗传播到临床实践的方法。