Community Health Effects of Industrial Hog Operations

工业化生猪养殖对社区健康的影响

• 批准号: 6777632
• 负责人: Steven B Wing
• 金额: $ 36.06万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2006-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6777632
• 关键词: air pollution; air sampling /monitoring; clinical research; community health services; disease /disorder proneness /risk; emotions; environmental exposure; epidemiology; gastrointestinal disorder; health services research tag; human subject; industrial waste; interview; longitudinal human study; medically underserved population; odors; pollution related respiratory disorder; public health; quality of life; questionnaires; sensory discrimination; spirometry; statistics /biometry; swine; water pollution; water sampling /testing

DESCRIPTION (provided by applicant): Recent expansion of large scale confined animal feeding operations (CAFOs) is generating a wide variety of health concerns in the USA and other nations. Air and ground water pollution from swine CAFOs are of particular concern in North Carolina, where industrial hog production has expanded rapidly since the 1980s. Airborne emissions are composed of hundreds of agents including hydrogen sulfide, ammonia, volatile organic compounds, and dusts or particulate matter that contains biological materials including proteins and endotoxins. Nitrates, pathogens, and antibiotic residues have been documented in ground water near swine CAFOs. The investigators propose a series of community-based participatory studies that will (1) quantify community exposures to hydrogen sulfide, volatile organic compounds, dusts, and endotoxins; (2) evaluate relationships between air emissions and perceptions of odor and irritation; (3) measure exposures to airborne emissions from livestock operations to strengthen the design of an already-funded health symptom survey; and (4) prospectively quantify relationships between ambient exposures and respiratory symptoms, lung function, and other health status measures among persons residing near swine CAFOs in North Carolina. They will also (5) conduct surveillance for nitrates and antibiotic residues in well water of study participants. Bacterial flora of any participants who report a history of drinking water contaminated by veterinary antibiotic residues will be tested for antibiotic resistance. Due to widespread distrust of biomedical research in poor and people of color communities where NC swine CAFOs are concentrated, community-based participatory research approaches are required for addressing these health issues. The proposed studies build on five years of community-driven research conducted by Concerned Citizens of Tillery and the University of North Carolina School of Public Health, as well as on extensive research on chemical odorants and their effects, and on water quality, conducted by other project collaborators. This project will provide new scientific data on exposures and human health effects of swine CAFOs and increase the capacity of communities in eastern NC to improve public health conditions in an underdeveloped region of the United States.

描述（由申请人提供）： 大规模限制动物喂养操作（CAFO）的最新扩展是 在美国和其他国家产生了各种各样的健康问题。 猪CAFO的空气和地下水污染在 北卡罗来纳州，自从工业猪的生产迅速扩大以来 1980年代。 空气传播的排放由数百个代理组成 硫化氢，氨，挥发性有机化合物和灰尘或 颗粒物包含包括蛋白质在内的生物材料和 内毒素。 已经记录了硝酸盐，病原体和抗生素残留物 在猪咖啡馆附近的地下水中。 调查人员提出了一系列 基于社区的参与研究将（1）量化社区 暴露于硫化氢，挥发性有机化合物，灰尘和 内毒素； （2）评估空气排放与看法之间的关系 气味和刺激； （3）测量对空中排放的暴露 牲畜操作以加强已经资助的健康的设计 症状调查； （4）前瞻性量化环境之间的关系 暴露和呼吸症状，肺功能和其他健康状况 居住在北卡罗来纳州猪咖啡馆附近的人之间的措施。 他们会的 （5）井中对硝酸盐和抗生素残基进行监视 研究参与者的水。 任何报告的参与者的细菌菌群 兽医抗生素残留污染的饮用水历史将 对抗生素耐药性进行测试。 由于生物医学的普遍不信任 在NC Cafos所在的穷人和颜色社区中的研究 需要集中，基于社区的参与研究方法 解决这些健康问题。 拟议的研究基于五年 由蒂勒里（Tillery）和 北卡罗来纳大学公共卫生学院以及 关于化学气味及其作用以及水的广泛研究 质量，由其他项目合作者进行。 这个项目将提供 有关猪CAFOS和人类健康影响的新科学数据和 提高北卡罗来纳州东部社区改善公共卫生的能力 美国欠发达地区的条件。