Improving Physical Activity and Fitness in Comorbidity

改善合并症的体力活动和健康

• 批准号: 6794013
• 负责人: ELIZABETH Ann SCHLENK
• 金额: $ 8.15万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794013
• 关键词: aerobic exercise; behavioral /social science research tag; breath tests; cardiovascular disorder prevention; cardiovascular disorder risk; cardiovascular function; clinical research; comorbidity; glucose tolerance; human middle age (35-64); human old age (65+); human subject; knee; longitudinal human study; muscle strength; osteoarthritis; personal log /diary; physical fitness; physical therapy; statistics /biometry; telecommunications; therapy compliance; videotape /videodisc

DESCRIPTION (provided by applicant): The long-term goal of the candidate in this KO1 application is to launch a focused and sustained program of research in the barriers that inhibit and the potential strategies that facilitate physical activity and improved cardiorespiratory fitness among persons with cardiovascular (CV) risk. Despite the health benefits of physical activity, 51 percent of persons age 65 to 74 engage in no physical activity. A primary national health goal, identified in Healthy People 2010, is to increase the proportion of adults who engage regularly, preferably daily, in moderate physical activity for at least 30 minutes. In no population is this more important than in those with CV risk. A prevalent and significant CV risk factor is impaired fasting glucose (IFG). About 13.6 million Americans have IFG. A significant barrier to physical activity in this population is imposed by osteoarthritis (OA) of the knee, a condition found in at least 2.5 million persons with IFG. Only 15 percent of persons with OA participate in regular physical activity. The underlying pathology can be managed through a program of quadriceps strengthening and graduated walking, yet only half engage in these exercises. A first step in the development of a regular physical activity program of potential benefit to CV disease prevention among older adults may be to address the barrier of OA of the knee. No work has been done in this area. Using a randomized controlled design, we propose to determine whether a self-efficacy based intervention designed to promote adherence to quadriceps strengthening and subsequent walking results in adherence to knee exercise, adoption (6 months) and maintenance (12 months) of regular physical activity (walking), and improvements in cardiorespiratory fitness in a convenience sample of 48 persons age 50 or older with IFG and OA of the knee. Subjects will be randomized to the 24-week intervention or to usual care and assessed at the baseline period, end of the intervention period, and 6 months after the intervention period ends using self-report and electronic pedometer measures of exercise, maximal graded cycle ergometer exercise tests, and an exercise self-efficacy measure. The intervention will incorporate strategies based on self-efficacy theory and consist of six individualized weekly sessions with a physical therapist followed by nine biweekly telephone delivered counseling sessions with a nurse. Data will be analyzed using repeated measures regression techniques.

描述（由申请人提供）：候选人在本次申请中的长期目标是在障碍中启动一项重点且持续的研究计划，这些障碍以及促进心血管（CV）风险患者的身体活动和改善心肺健康的潜在策略。尽管有体育锻炼的健康益处，但有51％的65至74岁的人没有进行任何体育锻炼。在2010年健康人中确定的主要国家健康目标是增加定期（最好每天）进行适度体育锻炼的成年人的比例至少30分钟。在任何人群中，这都比有简历风险的人更重要。禁食葡萄糖（IFG）流行而重要的CV风险因素受损。大约有1360万美国人有IFG。膝盖的骨关节炎（OA）施加了这一人群中体育活动的重大障碍，膝盖的骨关节炎（OA）至少有250万患有IFG的人。 OA只有15％的人参加常规体育锻炼。可以通过股四头肌加强和逐步步行的计划来管理基本的病理学，但只有一半从事这些运动。开发常规体育锻炼计划的第一步，该计划对预防老年人的CV疾病预防疾病的潜在益处可能是解决膝盖OA的障碍。该领域没有做任何工作。我们建议使用随机控制的设计，确定旨在促进依从股四头肌增强和随后的步行的基于自我效能的干预措施是否会导致遵守膝盖运动，采用（6个月）和定期体育锻炼（12个月）的定期体育锻炼（步行）（步行）（步行），以及在48岁或老年人年龄较老的情况下进行培训样本，并改善心脏呼吸型适应性。受试者将被随机分配给24周的干预措施或通常的护理，并在干预期结束后的基线周期，干预期结束后进行评估，并使用自我报告和电子计量计的运动计量，最大分级循环测试测试和运动自我效能测量。该干预措施将根据自我效能理论纳入策略，并由六个个性化的每周课程与物理治疗师一起，然后与护士一起进行九次每两周一次的电话进行咨询。将使用重复测量回归技术分析数据。