Integrated Health Sciences Facility Core

综合健康科学设施核心

• 批准号: 9058298
• 负责人: Sioban D Harlow
• 金额: $ 20.28万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-15 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9058298
• 关键词: Animals; Award; Bayesian Method; Charge; Chronic Disease; Clinical Research; Clinical Sciences; Collaborations; Consult; Consultations; Core Facility; Data; Development; Disease; Educational workshop; Ensure; Environmental Exposure; Environmental Health; Environmental Risk Factor; Epidemiology; Epigenetic Process; Fostering; Geographic Information Systems; Goals; Grant; Health; Health Sciences; Human; Intervention; Laboratories; Life; Life Cycle Stages; Link; Location; Methods; Michigan; Mission; Online Systems; Play; Policies; Population Sciences; Professional Practice; Protocols documentation; Public Health Informatics; Public Health Practice; Public Health Schools; Research; Research Design; Research Personnel; Resources; Risk; Sampling; Scholarship; Science; Services; Specimen; Staging; Statistical Data Interpretation; Statistical Methods; Students; Teacher Professional Development; Technology; Translational Research; Translations; United States National Institutes of Health; Universities; Update; Work; animal population study; biobank; clinical practice; cohort; education research; epigenomics; gene environment interaction; health practice; information kiosk; interdisciplinary collaboration; member; outreach; pollutant; programs; repository; sample collection; sound; statistical center; statistics

SUMMARY/ABSTRACT (Integrated Health Sciences Core) M-LEEaD’s mission is to accelerate research that defines the impact of environmental exposures during vulnerable life stages and to promote translation of research findings to interventions that mitigate chronic disease. In support of this mission, the M-LEEaD Integrated Health Sciences Core (IHSC) promotes multi-directional translational research using integrated multi-disciplinary approaches with the goal of advancing understanding of the impact of environmental exposures across the life- course on risk of chronic disease. In this competing renewal, we have restructured the IHSC and have incorporated the former Environmental Statistics Core in order to maximize efficiency and integrate overlapping functions. A new component of the IHSC is the environmental health practice team in charge of overseeing outreach to the state and regional professional practice. The IHSC specific objectives are: 1) to facilitate interaction between basic, mechanistic and toxicological science, population sciences, clinical research and practice professionals through the searchable, web-based information kiosk (the M-LEEaD Repository Kiosk), annual workshops and weekly seminars; 2) to optimize the value and utilization of our large human and animal specimen and data resources for environmental health research through the M-LEEaD Repository Kiosk; and 3) to promote sound study design, quality specimen collection, and rigorous statistical analysis, as well as the development of statistical methods and collaborations to advance environmental research through our consultation services, seminars, and workshops. A distinctive feature of the IHSC core is that our services are not related to a specific technology. Rather, the IHSC provides a critical linkage function promoting translational scholarship and multi-directional stakeholder partnerships. We provide consulting services to ensure quality of research designs, exposure assessment, laboratory analyses, and analytic methods, with specific guidance on establishing and maximizing utilization of human and animal biobanks. We capitalize on the rich set of NIH supported studies led by center members that encompass a wide range of exposures and life-stages through the M-LEEaD Repository Kiosk providing information about research opportunities within these well-defined human population and animal studies, and their associated data and bio-repositories. On the statistical front, the IHSC develops and consults on cutting-edge statistical methods to advance environmental health. The IHSC aims to facilitate translation to practice and policy by hosting two annual workshops, one focused on environmental statistics and one focused on Environmental Health Practice.

摘要/摘要（综合健康科学核心） M-LEEaD 的使命是加速定义环境暴露影响的研究 在脆弱的生命阶段，并促进将研究成果转化为干预措施 为了支持这一使命，M-LEEaD 综合健康科学核心。 （IHSC）利用综合多学科方法促进多方向转化研究 其目标是加深对环境暴露对生命周期影响的了解 在这次竞争更新中，我们重组了 IHSC，并制定了有关慢性病风险的课程。 纳入前环境统计核心，以最大限度地提高效率并整合 IHSC 的一个新组成部分是环境健康实践团队。 负责监督州和地区专业实践的推广。 目标是： 1) 促进基础科学、机械科学和毒理学科学之间的相互作用， 人口科学、临床研究和实践专业人员通过可搜索的、基于网络的 信息亭（M-LEEaD 存储库亭）、年度研讨会和每周研讨会 2) 优化我们大量人类和动物标本和数据资源的价值和利用 通过 M-LEEaD 存储库进行环境健康研究；3) 促进健全研究； 设计、高质量样本采集、严格的统计分析以及开发 通过我们的咨询推进环境研究的统计方法和合作 IHSC 核心的一个显着特点是我们的服务不包括服务、研讨会和讲习班。 相反，IHSC 提供了促进特定技术的关键链接功能。 我们提供转化奖学金和多向利益相关者合作伙伴关系。 确保研究设计、暴露评估、实验室分析和 分析方法，对建立和最大限度地利用人力和物力提供具体指导 我们利用由中心成员领导的 NIH 支持的丰富研究。 通过 M-LEEaD 存储库信息亭涵盖广泛的暴露和生命阶段 提供有关这些明确人群中的研究机会的信息，以及 在统计方面，IHSC 负责动物研究及其相关数据和生物数据库。 IHSC 开发先进的统计方法并提供咨询，以促进环境健康。 旨在通过举办两场年度研讨会促进实践和政策转化，其中一场重点关注 环境统计，其中一项重点关注环境健康实践。