Applied Biology and Bioprocess Engineering Training

应用生物学和生物过程工程培训

• 批准号: 6749321
• 负责人: HARVEY W BLANCH
• 金额: $ 25.9万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-09-27 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6749321
• 关键词: Applied; Biology; Bioprocess; Engineering; Training

DESCRIPTION (provided by applicant): Purpose and Program Characteristics The purpose of the Applied Biology and Biotechnology training program is to provide a curriculum and research environment that prepares trainees in chemical and bioengineering, biological chemistry, cell and molecular biology at the predoctoral level for careers in biotechnology. Specifically, this program focuses on research training in areas relevant to the needs of biotechnology, pharmaceutical and chemical companies currently involved in the manufacture of products using biological routes. Trainees acquire expertise in areas such as molecular genetics, bacterial, yeast and fungal fermentation, mammalian cell culture, enzyme technology, bioproduct recovery and purification, combinatorial biocatalysis and chemistry, and biomedical applications of materials science and bioengineering. The graduate program includes laboratory and classroom instruction in cell culture techniques (mammalian and bacteria cell culture), protein and enzyme isolation, purification and immobilization, mutagenesis and gene expression, protein and nucleic acid chemistry and biochemistry, separation and purification methods, biosensors and bioinformatics. This is supplemented with seminar courses on topics spanning industrial research and development activities and advanced scientific areas, including fermentations involving recombinant organisms, tissue engineering, bioproduct recovery (including macromolecular separations), site-directed mutagenesis techniques, metabolic regulation, enzyme inhibitor design and the application of enzymes and antibodies as catalysts in organic syntheses. Lectures from internationally known scientists in a variety of related disciplines further enrich the training program. Research is conducted in the various areas described above under the supervision of the faculty mentors. Students also undertake an industrial internship during the course of their traineeship, typically at Bay Area biotechnology companies. Trainees Predoctoral students will enter the program with varying backgrounds, all holding Baccalaureate degrees in engineering or science (some with Masters degrees), and some with previous industrial experience. They will be selected on the basis of undergraduate scholastic performance, scores on GRE tests, recommendations from faculty at their undergraduate institutions and from their Berkeley mentors. Support for 12 trainees is requested. The average duration of the doctoral program in the participating departments is 5.5 years.

描述（由申请人提供）： 目的和程序特征 应用生物学和生物技术培训计划的目的是提供一个课程和研究环境，为在生物技术职业的专业水平上为化学和生物工程，生物化学，细胞和分子生物学的学者做好准备。具体而言，该计划重点介绍与生物技术，药物和化学公司目前参与使用生物学途径生产产品的领域的研究培训。受训者获得了分子遗传学，细菌，酵母和真菌发酵，哺乳动物细胞培养，酶技术，生物产品恢复和纯化，联合生物催化和化学的酶的专业知识，以及材料科学和生物工程的生物医学应用。 该研究生课程包括细胞培养技术（哺乳动物和细菌细胞培养），蛋白质和酶隔离，纯化和固定化，诱变和基因表达，蛋白质和核酸化学以及生物化学，分离和纯化方法，生物发音和生物发音方法和生物化学方法的实验室和课堂教学。 This is supplemented with seminar courses on topics spanning industrial research and development activities and advanced scientific areas, including fermentations involving recombinant organisms, tissue engineering, bioproduct recovery (including macromolecular separations), site-directed mutagenesis techniques, metabolic regulation, enzyme inhibitor design and the application of enzymes and antibodies as catalysts in organic syntheses.来自国际知名科学家的各种相关学科的讲座进一步丰富了培训计划。在教师导师的监督下，在上面描述的各个领域进行了研究。学生们在培训期间还在湾区生物技术公司进行工业实习。 学员 专业学生将以不同的背景进入该计划，所有这些都拥有工程或科学学士学位（有些具有硕士学位），有些则具有以前的工业经验。他们将根据本科学业表现，GRE测试的分数，本科机构的教师的建议以及伯克利导师的建议选择。要求支持12名学员。参与部门的博士课程的平均持续时间为5。5年。