APPLIED BIOLOGY AND BIOPROCESS ENGINEERING TRAINING

应用生物学和生物工艺工程培训

• 批准号: 6150879
• 负责人: HARVEY W BLANCH
• 金额: $ 18.07万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-09-27 至 2004-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6150879
• 关键词: APPLIED; BIOLOGY; BIOPROCESS; ENGINEERING; TRAINING

Purpose and Program Characteristics The purpose of this training program is to provide a curriculum and research environment that will prepare trainees in chemical engineering, chemistry and cell and molecular biology at the predoctoral level for careers in biotechnology. Specifically, this program focuses on research training in areas relevant to the needs of biotechnology, pharmaceutical and chemical companies currently involved in the manufacture of products using biological routes and includes areas such as molecular genetics, fermentation, mammalian cell culture, enzyme technology, bioproduct recovery, combinatorial biocatalysis, combinatorial chemistry. The graduate program includes laboratory and classroom instruction in cell culture techniques (mammalian and bacteria cell culture), protein and enzyme isolation, purification and immobilization, mutagenesis and gene expression, protein and nucleic acid chemistry and biochemistry, and separation and purification methods. This will be supplemented with seminar courses on current topics in industrial and scientific areas, including fermentations involving recombinant organisms, bioproduct recovery (including macromolecular separations), site-directed mutagenesis techniques, metabolic regulation, enzyme inhibitor design and the application of enzymes and antibodies as catalysts in organic syntheses. Lectures from internationally known guests in a variety of related disciplines will further enrich the training program. Research will be conducted in the various area described above under the supervision of the faculty mentors. Trainees Predoctoral students will enter the program with varying backgrounds, all holding Baccalaureate degrees in engineering or science (some with Masters degrees). They will be selected on the basis of undergraduate scholastic performance, scores on GRE tests and recommendations from faculty at their undergraduate institutions. Support for 12 trainees is requested. The average duration of the doctoral program in the participating departments is 5.5 years.

目的和计划特征该培训计划的目的是提供课程和研究环境，该课程将在化学工程，化学和细胞和分子生物学领域的学员在生物技术职业中为学员准备。具体而言，该计划的重点是与生物技术，药物和化学公司有关的领域的研究培训，目前使用生物学途径参与制造产品，包括分子遗传学，发酵，哺乳动物细胞培养，酶技术，生物产物技术，生物产物恢复，结合生物生物剖析，结合性生物剖析，组合量，结合化学。研究生课程包括细胞培养技术（哺乳动物和细菌细胞培养），蛋白质和酶分离，纯化和固定化，诱变和基因表达，蛋白质和核酸化学和生物化学，以及分离和净化方法的实验室和课堂教学。 This will be supplemented with seminar courses on current topics in industrial and scientific areas, including fermentations involving recombinant organisms, bioproduct recovery (including macromolecular separations), site-directed mutagenesis techniques, metabolic regulation, enzyme inhibitor design and the application of enzymes and antibodies as catalysts in organic syntheses.在各种相关学科中，国际知名客人的讲座将进一步丰富培训计划。研究将在教师导师的监督下在上面描述的各个领域进行。学员前学生将以不同的背景进入该计划，所有这些都拥有工程或科学学士学位（有些具有硕士学位）。他们将根据本科学业表现，GRE测试的分数以及其本科机构的教职员工的建议选择。要求支持12名学员。参与部门的博士课程的平均持续时间为5。5年。