Neural Control of Breathing and Cardiovascular Function

呼吸和心血管功能的神经控制

• 批准号: 6801509
• 负责人: MUSA A HAXHIU
• 金额: $ 13.08万
• 依托单位: HOWARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6801509
• 关键词: Neural; Control; Breathing; Cardiovascular; Function

DESCRIPTION (provided by applicant): This application seeks support to train scientific leaders in neural control of breathing and circulation. This program will support Ph.D. graduate students that will be selected based on undergraduate performance and their relevant research interest for their future careers. We have designed an integrated training program to prepare these future scientists to apply their skills to problems in pulmonary and cardiovascular functional disorders in relation to neuronal, behavioral and chemical control of breathing, and cardiovascular functions. Over the last 30 years the Ph.D. training program in Physiology and Biophysics, with particular emphasis on respiratory and cardiovascular control has graduated more than 30 trainees who are in research and teaching throughout the U.S. Under the leadership of Dr. M. A. Haxhiu as Program Director, Drs. C. Ovid Trouth and V. J. Massari as Program Co-Directors, and Dr. B. R. Coleman, Departmental Chairperson, we are committed to focus and intensify research on neural and hormonal control of breathing, airways, and circulation. This will be accomplished by, building on current research programs and maximizing our strengths in neuroscience, respiration and cardiovascular physiology, and expanding existing collaborations with established investigators in the Departments of Anatomy, Biochemistry, Pharmacology, Biology and Medicine. Our program faculties at Howard University and at the Collaborative Intensive Research Institutions are comprised of well established scientists, experienced trainers, and NIH-supported investigators who are working in interrelated areas of neural and hormonal control of breathing, airways and the cardiovascular system, all of which encompass both basic biologic and clinical components. Students may choose to focus their research project in control of breathing, airway functions, or the cardiovascular system. The availability of experienced mentorship and outstanding Collaborative Research Faculty in these interrelated fields and the strong interaction between these fields are the major components of this proposal. A "Neural and Hormonal Control of Breathing and Circulation" Seminar Series will serve as a nucleus for the trainees from both fields by providing a formal curriculum and an interactive "research in progress" component. Graduate students will have the opportunity to select courses in the basic sciences and will be trained in manuscript and grant preparation, in teaching and communication. In collaboration with designated Faculty at Case Western Reserve University, Johns Hopkins University, Mayo Medical School, University of Michigan, University of Wisconsin, and Yale University, we will offer vigorous, focused mentorship that will motivate our trainees to develop solid academic careers.

描述（由申请人提供）：本申请寻求支持，以培训科学领导者的呼吸和流通神经控制。 该课程将支持博士学位。将根据本科表现及其对未来职业的相关研究兴趣而被选出的研究生。 我们设计了一项综合培训计划，以准备这些未来的科学家将其技能应用于与呼吸的神经元，行为和化学控制以及心血管功能有关的肺和心血管功能障碍问题。 在过去的30年中，博士学位生理学和生物物理学的培训计划，特别着重于呼吸道和心血管控制的培训计划，已在整个美国从事研究和教学的30多名学员，在M. A. Haxhiu博士的领导下，担任计划主任。 C. Ovid Trouth和V. J. Massari担任计划联合指导，以及部门主席B. R. Coleman博士，我们致力于重点并加强对呼吸，航空通道和流通的神经和荷尔蒙控制的研究。 这将通过建立当前的研究计划，并最大程度地提高我们在神经科学，呼吸和心血管生理学方面的优势来实现这一目标，并扩大与解剖学，生物化学，药理学，生物学和医学部门的既定研究人员的现有合作。 我们在霍华德大学（Howard University）和合作强化研究机构的课程学院由成熟的科学家，经验丰富的培训师和NIH支持的研究人员组成，他们正在呼吸，飞机和心血管系统的神经和荷尔蒙控制的相互关联领域工作，这些都涵盖了基本的生物学和临床组合。 学生可以选择将其研究项目集中在控制呼吸，气道功能或心血管系统上。 这些相互关联的领域的经验丰富的指导和杰出的合作研究学院的可用性以及这些领域之间的强烈互动是该提案的主要组成部分。 “呼吸和循环的神经和荷尔蒙控制”研讨会系列将通过提供正式的课程和交互式“正在进行的研究”组成部分来为来自两个领域的学员的核心。 研究生将有机会选择基础科学课程，并将接受手稿和授予准备，教学和交流的培训。 与Case Western Reserve大学，Johns Hopkins大学，密歇根大学，威斯康星大学和耶鲁大学的指定教师合作，我们将提供有力的，专注的指导，以激励我们的学员发展扎实的学术职业。