Surgical Monitor for Detection of Spinal Cord Injury

用于检测脊髓损伤的手术监视器

• 批准号: 6739144
• 负责人: HONGXUAN ZHANG
• 金额: $ 64.71万
• 依托单位: INFINITE BIOMEDICAL TECHNOLOGIES, LLC
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6739144
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; clinical research; computer program /software; electrophysiology; evoked potentials; human subject; nerve decompression; patient monitoring device; somesthetic sensory cortex; spinal cord injury; spinal cord surgery; surgery material /equipment

DESCRIPTION (provided by applicant): Somatosensory evoked potential (SEP) monitoring during spinal surgery has been associated with a 61% reduction in major neurological deficits. However, visual interpretation of signals is not always accurate, and a significant learning curve has been demonstrated. Therefore, we embarked on a course to develop a novel SEP monitor equipped with the latest in wireless and digital signal processing technology to continuously monitor spinal cord function. We propose the development of a toolbox of techniques which will significantly advance spinal cord assessment during surgery, including:  Integration of noise reduction via single-sweep rejection and filtering  Investigation of the coherence of individual spectral components of the SEP and  Incorporation of wireless multi-channel stimulation & monitoring  Evaluation of the resulting next-generation real-time monitor in a clinical study It is our vision to translate these hardware and software innovations into a useful device to assist the clinician in improving the outcome of the patient undergoing spinal surgery.

描述（由申请人提供）：脊柱手术期间的体感诱发潜力（SEP）监测与主要神经系统缺陷降低61％有关。但是，信号的视觉解释并不总是准确的，并且已经证明了一个重要的学习曲线。因此，我们启动了一门课程，开发了配备了最新无线和数字信号处理技术的新型SEP监视器，以连续监视脊髓功能。我们建议开发一种技术工具箱，该工具将在手术过程中大大提高脊髓评估，包括： 通过单扫描和过滤整合降噪的集成 调查SEP和SEP单个光谱成分的相干性和 无线多通道刺激和监测的合并 在临床研究中评估由此产生的下一代实时监测 我们的愿景将这些硬件和软件创新转化为有用的设备，以帮助临床医生改善接受脊柱手术的患者的结果。