Religion and support for genomic healthcare: An exploratory study of the US public and faith leaders.

宗教和对基因组医疗保健的支持：对美国公众和信仰领袖的探索性研究。

基本信息

批准号：
10708964
负责人：
James M Dubois
金额：
$ 47.39万
依托单位：
WASHINGTON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-22 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10708964
关键词：
Address Adoption Adult Attitude Belief Bible Black Populations Black race COVID-19 vaccine Cessation of life Characteristics Christianity Communities Data Education Educational Status Ensure Faith Faith leader Frequencies Genes Genetic Genomics Health Technology Healthcare Healthcare Activity Healthcare Systems Hispanic Populations Human Interview Knowledge Learning Life Measurement Messenger RNA Modeling Morals Muslim population group Muslim religion National Human Genome Research Institute Participant Persons Play Population Prayers Protestant Public Health Qualitative Research RNA vaccine Regression Analysis Religion Research Research Methodology Research Personnel Risk Role Rural Population Sample Size Sampling Scientist Services Shapes Subgroup Surveys Technology ethical, legal, and social implication experience follower of religion Jewish genetic testing health disparity innovation instrument interest new technology prenatal religious group response stakeholder perspectives stem stem cell therapy

项目摘要

Project Summary Religion is a primary driver of concerns with genomics and genomic healthcare (GGH). It is vital for research on the ethical, legal, and social implications (ELSI) of genomics to understand the role of religion in shaping public attitudes toward GGH. Ninety percent of the US public believes in some kind of higher power and 55% pray daily. The US public attends religious services at a rate 3 times higher than scientists in the US, who are at risk of misunderstanding the role religion plays in attitudes toward GGH. Further, Black, Hispanic, and rural populations attend religious services more frequently than the general US public. Concerns with GGH activities may lead to lower levels of engagement of GGH, which may in turn contribute to health disparities. This project aims to understand why higher levels of religious practice are associated with greater concerns with GGH activities. Additionally, this project will interview faith leaders to identify how public health genomics might engage faith communities in ways that are respectful and constructive. While some concerns with healthcare technologies may disappear with new information, others stem from worldviews, deep moral commitments, or mistrust of the healthcare system. Engaging religious communities is essential to identify which concerns can be addressed with information, which call for alternative responses, and what alternative responses might look like. Very few models exist for genomic public health engagement with religion, particularly models that directly address value-laden concerns.13,14 This project will achieve two specific aims: 1. Quantitatively examine which aspects of religion explain its influence on support for GGH activities. We will survey 4800 adults in the US to examine the association of religious variables with support for GGH activities such as prenatal genetic testing, gene editing, and mRNA vaccines. We will generate rich descriptive data and explore how and when diverse religious variables predict support for, or opposition to, GGH activities. 2. Explore how genomic public health can engage with religious communities in a way that is respectful and constructive. We will conduct in-depth interviews via Zoom with 180 faith leaders—30 from each of six groups: Evangelical, Mainline Protestant, Historically Black, and Catholic Christianity, Judaism, and Islam. These groups represent the largest religious groups in the US, comprising 90% of those with a religious affiliation. Interviews will explore several different issues: What are their views on GGH activities? Is diversity of opinion on these matters tolerated within their community? To what extent are concerns with GGH activities principled and to what extent might further information be helpful? How might genomic public health engage religious communities in a way that is both respectful and constructive?

项目概要宗教是基因组学和基因组医疗保健 (GGH) 关注的主要驱动力，这对于研究至关重要。基因组学的伦理、法律和社会影响（ELSI），以了解宗教在塑造 90% 的美国公众相信某种更高的权力，55% 的公众对 GGH 的态度。美国公众每天参加宗教仪式的比例是美国科学家的三倍。存在误解宗教在对待 GGH 的态度中所扮演的角色的风险，包括黑人、西班牙裔和农村人。民众参加宗教仪式的频率高于美国公众对 GGH 的担忧。活动可能会导致 GGH 的参与程度降低，进而可能导致健康差异。该项目旨在了解为什么更高水平的宗教实践与更大的关注相关与 GGH 活动。此外，该项目将采访信仰领袖，以确定公共卫生基因组学如何参与以尊重和建设性的方式信仰社区，但对医疗保健有些担忧。技术可能会随着新信息而消失，其他技术则源于世界观、深刻的道德承诺、或对医疗保健系统的不信任对于确定哪些问题至关重要。可以通过信息来解决，这些信息需要替代反应，以及哪些替代反应可能基因组公共卫生与宗教的互动模型很少，尤其是这样的模型。直接解决充满价值的问题。13,14 该项目将实现两个具体目标： 1. 定量研究宗教的哪些方面解释了其对 GGH 活动支持的影响。我们将调查 4800 名美国成年人，以检验宗教变量与 GGH 支持之间的关联产前基因检测、基因编辑和 mRNA 疫苗等活动我们将生成丰富的描述性内容。数据并探索宗教变量如何以及何时预测对 GGH 活动的支持或反对。 2. 探索基因组公共卫生如何以一种能够与宗教社区互动的方式我们将通过 Zoom 与 180 名信仰领袖进行深入采访，其中 30 名来自六个群体中的每一个：福音派、主流新教、历史黑人、天主教、犹太教、这些团体代表了美国最大的宗教团体，占其中的 90%。访谈将探讨几个不同的问题：他们对 GGH 活动有何看法？他们的社区对这些问题的不同意见在多大程度上可以被容忍？活动 d 以及进一步的主要信息对基因组公共卫生有何帮助？以尊重和建设性的方式参与宗教社区？