Remote Telemetry for Neural Recording and Stimulation

用于神经记录和刺激的远程遥测

• 批准号: 6694584
• 负责人: JON P JOSEPH
• 金额: $ 9.96万
• 依托单位: CYBERKINETICS NEUROTECHNOLOGY SYSTEMS
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2005-08-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6694584
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; computer program /software; computer system design /evaluation; electronic recording system; electronic stimulator; miniature biomedical equipment; telemetry

DESCRIPTION (provided by applicant): The goal of this program is to create miniature, low-power neural signal recording and stimulation systems that can be controlled by short range (<10m) telemetry for neuropsychological experiments. These systems will be integrated into head-mounted packages and provide untethered recording and stimulation interfaces for up to 128 extracellular electrodes for animals as small as mice and rats. The systems will consist of recently developed VLSI neural signal amplifier and stimulation components, and commercial, off-the-shelf analog-to-digital converters, programmable logic, and telemetry components. In Phase I of this program, we will investigate the feasibility of 3 different telemetry modes: (1) Infrared serial data, (2) Frequency Shift Keying (FSK) modulated RF in the 900 MHz and 2.4GHz ISM bands, (3) Ultra-Wide Band (UWB) modulated RF in the 3.1GHz to 10.6GHz UWB communications band. This phase will include parametric testing of commercially available parts for these telemetry modes and testing of prototype systems to investigate telemetry performance and interference with neural recording. In Phase II of this program, we will select the best telemetry modules and develop the final head-mounted systems and all of the external support hardware and software for using these systems in neurophysiological experiments. These external components will include the telemetry base stations and a flexible digital I/O interface for data acquisition and stimulation control along with Graphical User Interface software to control the system configuration.

描述（由申请人提供）：该程序的目的是创建微型，低功率的神经信号记录和刺激系统，可以通过短范围（<10m）遥测来控制神经心理学实验。 这些系统将集成到头部安装的包装中，并为多达128个小鼠和大鼠的动物提供不受限制的记录和刺激界面。该系统将由最近开发的VLSI神经信号放大器和刺激成分以及商业，现成的类似于数字的转换器，可编程逻辑和遥测组件组成。 在该程序的第一阶段中，我们将研究3种不同遥测模式的可行性：（1）红外序列数据，（2）900 MHz和2.4GHz ISM频段中的频移键（FSK）调制的RF，（3）超宽带（UWB）在3.1GHz至10.6GHZ至10.6GHZ UWB Communicy communication中。此阶段将包括对这些遥测模式的市售零件的参数测试以及原型系统的测试，以研究遥测性能并干扰神经记录。 在该计划的第二阶段中，我们将选择最佳的遥测模块，并开发最终的头部安装系统以及所有用于在神经生理实验中使用这些系统的外部支持硬件和软件。这些外部组件将包括遥测基站和灵活的数字I/O接口，用于数据采集和刺激控制以及图形用户界面软件，以控制系统配置。