Prevention of depression among adolescents in Iceland

冰岛青少年抑郁症的预防

• 批准号: 6680224
• 负责人: W. EDWARD CRAIGHEAD
• 金额: $ 7.21万
• 依托单位: UNIVERSITY OF COLORADO
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-16 至 2005-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6680224
• 关键词: Scandinavian country; academic achievement; adolescence (12-20); behavioral /social science research tag; clinical research; disease /disorder proneness /risk; group therapy; high risk behavior /lifestyle; human subject; interpersonal relations; interview; longitudinal human study; major depression; mental disorder prevention; problem solving; questionnaires; secondary schools

DESCRIPTION (provided by applicant): Major Depressive Disorder (MDD) is a prevalent and debilitating clinical problem in every country in which it has been studied. In recent decades, the rate of first episode of MDD has been increasing among adolescents, so that the highest rate of first onset is now among those in the 15-25 age range. Furthermore, MDD is a highly recurrent disorder, with individuals who experience one episode having over a 50% probability of subsequent episodes. Thus, prevention of the first episode of MDD is an important and significant health issue. We have incorporated findings from human development and empirical clinical research with adolescents into a manualized, school-based program designed to prevent MDD among those who are at risk for the development of the disorder. Within a developmental context, the 14-session program is based on principles of problem solving, interpersonal, behavioral, and cognitive studies of adolescent depression. A school psychologist, who is a school employee, will lead the program within a small-group format. In the proposed project we plan to implement and evaluate the success of this program with a group of Icelandic adolescents who are "at risk" for the first episode of MDD. "At risk" is defined as never having suffered from diagnosable MDD and: 1) scoring 13 or higher on the CDI; 2) scoring 75th percentile or higher on CASQNEG; 3) scoring 25th percentile or lower on CAS-POS; OR, 4) scoring 25th percentile or lower on CASQ-POS minus CASQ-NEG. Participants will be 96 "at risk" ninth grade (age 14) students, who will be randomly assigned to either the prevention program or to an "assessment only" control group. The program will be conducted throughout one entire school year, and then participants will be followed for a second year. All participants will be evaluated at the beginning and end of the program and at the beginning and end of the second school year of the project. This project will provide valuable information for the new selection criteria and feasibility data regarding a larger prevention program throughout Iceland. Data from this project will inform and provide guidelines for a subsequent larger prevention program in Iceland and in other countries.

描述（由申请人提供）：主要抑郁症（MDD）是每个研究的国家中普遍且令人衰弱的临床问题。在最近的几十年中，MDD的第一集的速度一直在增加青少年，因此，在15-25岁年龄段的人群中，最高的第一发率是最高的发作率。此外，MDD是一种高度复发性的疾病，其个人经历了一个发作，其后续发作的可能性超过50％。因此，预防MDD的第一集是一个重要而重要的健康问题。 我们已经将人类发展和经验临床研究的发现与青少年一起纳入了一项手动的，基于学校的计划，旨在防止有疾病发育风险的人中的MDD。 在发展背景下，14条课程基于青少年抑郁症的解决问题，人际关系，行为和认知研究的原则。学校心理学家是一名学校员工，将以小组格式领导该计划。在拟议的项目中，我们计划与一群在MDD第一集中“有风险”的冰岛青少年实施和评估该计划的成功。 “处于危险之中”定义为从未遭受可诊断的MDD遭受的痛苦，1）在CDI上得分13或更高； 2）在Casqneg上得分75个百分点或更高； 3）在CAS-POS上得分25％或更低；或者，4）在CASQ-POS减去CASQ-NEG上得分25％或更低。参与者将为96“处于危险中”的九年级（14岁）学生，他们将被随机分配到预防计划或“仅评估”对照组。该计划将在整个学年中进行，然后遵循第二年的参与者。所有参与者将在计划的开始和结尾以及项目第二学年的开始和结束时进行评估。该项目将提供有关冰岛整个较大预防计划的新选择标准和可行性数据的宝贵信息。该项目的数据将为冰岛和其他国家的随后的大型预防计划提供信息并提供指南。