The West Virginia Pediatric Clinical Trials Network

西弗吉尼亚州儿科临床试验网络

基本信息

批准号：
9461966
负责人：
LESLEY A COTTRELL
金额：
$ 181.14万
依托单位：
WEST VIRGINIA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-09-23 至 2020-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9461966
关键词：
West Virginia Pediatric Clinical Trials

项目摘要

Abstract The West Virginia Pediatric Clinical Trials Network (WVPCTN) will work as a Clinical Center of the IDeA States PCTN to provide clinical trial access to individuals in the rural, central Appalachian state of West Virginia and surrounding counties included in the immediate service area. The WVPCTN will be critically poised to serve as a Clinical Center based on the historical, physical, psychosocial, and fiscal burdens brought about by a multitude of chronic disease conditions and a wide variety of environmental risk factors that contribute to those conditions in West Virginia. The WVPCTN is well positioned to be successful as a Clinical Center due to a combination of a variety of structural and human resources already in place that address: Subject Identification, Subject Recruitment and Study Performance. Specifically, the WVPCTN will utilize the following: for Subject Identification - the Integrated Data Repository of the WVU CTSI (containing over 2 million patient records), large neonatal and school age cohorts from our Birth Score and CARDIAC projects (described in detail in the Research Plan), and targeted cohorts from the West Virginia Perinatal Partnership Network, the Center of Excellence in Disabilities and the WVU Department of Occupational and Environmental Studies; for Subject Recruitment – WVU General and Specialty Clinics, our CTSI sponsored Practice Based Research Network, the infrastructure of our Dental COHRA grant, the infrastructure from Birth Score and CARDIAC, and a variety of specialized existing settings; for Study Performance – an experienced investigator pool, a group of mentee investigators, and the resources and oversight of the WVU CTSI sponsored Clinical Trials Research Unit core. These features and resources, together with strong and sustained partnerships throughout the state, and the multiple environmentally related conditions of our citizens, uniquely position us to both be successful at PCTN trials and propose new trials for the PCTN. The WVPCTN will add to a long standing commitment to pediatric focused initiatives across the state and benefit from statewide networks that have been established, in part through active IDeA State mechanisms. As such, we are uniquely positioned to fully leverage additional funds to efficiently establish the infrastructure to provide access to cutting edge trials which will impact the health of the children of West Virginia.

抽象的西弗吉尼亚州儿科临床试验网络 (WVPCTN) 将作为 IDeA 各州的临床中心 PCTN 将为西弗吉尼亚州中部阿巴拉契亚州农村地区的个人提供临床试验机会包括在直接服务区域内的周边县将做好充分准备，作为服务区域。一个基于大众带来的历史、身体、社会和财政负担的临床心理中心慢性疾病以及导致这些疾病的各种环境风险因素位于西弗吉尼亚州的 WVPCTN 凭借以下优势成为成功的临床中心：已经到位的各种结构和人力资源可以解决：主题识别、主题具体而言，WVPCTN 将利用以下内容：用于受试者识别。 - WVU CTSI 的综合数据存储库（包含超过 200 万条患者记录）、大型新生儿和来自我们的出生分数和 CARDIAC 项目的学龄群体（在研究计划中详细描述），以及来自西弗吉尼亚州围产期合作网络、残疾人卓越中心的目标群体和西弗吉尼亚大学职业与环境研究系；用于学科招募 - 西弗吉尼亚大学综合部和专科诊所、我们的 CTSI 赞助的基于实践的研究网络、我们牙科的基础设施 COHRA 拨款、出生评分和 CARDIAC 的基础设施以及各种专门的现有设置；研究绩效 – 经验丰富的研究人员库、一组受训研究人员以及资源以及对 WVU CTSI 赞助的临床试验研究单位核心的监督。与全州强有力和持续的合作伙伴关系以及与环境相关的多个我们公民的条件，使我们能够在 PCTN 试验中取得成功并提出新的试验 PCTN 将加强对全州儿科重点举措的长期承诺。并受益于已建立的联邦网络，部分是通过积极的 IDeA 国家机制。因此，我们具有独特的优势，可以充分利用额外资金来有效地建立基础设施提供最先进的试验，这将影响西弗吉尼亚州儿童的健康。

项目成果

期刊论文数量（3）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Predictors of Hypertension Development 1 Year After Heart Transplantation.

心脏移植后一年高血压发生的预测因素。

DOI：
发表时间：
2022-08-01
期刊：
影响因子：
6.2
作者：
Nygaard, Sissel;Christensen, Anders H;Sletner, Line;Rolid, Katrine;Nytrøen, Kari;Gullestad, Lars;Fiane, Arnt;Thaulow, Erik;Døhlen, Gaute;Saul, J Philip;Wyller, Vegard B B
通讯作者：
Wyller, Vegard B B

Early testing of insulin resistance: a tale of two lipid ratios in a group of 5th graders screened by the Coronary Artery Risk Detection in Appalachian Communities Project (CARDIAC Project).

胰岛素抵抗的早期测试：阿巴拉契亚社区冠状动脉风险检测项目（CARDIAC 项目）筛查的一组五年级学生的两种脂质比率的故事。

DOI：
发表时间：
2019-08
期刊：
影响因子：
0
作者：
Mosimah, Charles Ituka;Lilly, Christa;Forbin, Awung;Murray, Pamela J;Pyles, Lee;Elliot, Elloise;Neal, William
通讯作者：
Neal, William

"A Song of Ice and Fire"-another verse from the world of ablation.

《冰与火之歌》——又一首来自消融世界的诗句。