2017 Cell Biology of Metals Gordon Research Conference and Gordon Research Seminar

2017金属细胞生物学戈登研究会议暨戈登研究研讨会

• 批准号: 9328227
• 负责人: MICHAEL J. PETRIS
• 金额: $ 2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-22 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9328227
• 关键词: Academia; Applied Research; Area; Bacteria; Basic Science; Biochemistry; Biogenesis; Biological Models; Biology; Cells; Cellular biology; Chemistry; Collaborations; Columbidae; Communicable Diseases; Development; Discipline; Disease; Environment; Enzymes; Evaluation; Fertilization; Fostering; Future; Genetic; Goals; Government Agencies; Health; Homeostasis; Human; Industry; Institution; International; Ions; Knowledge; Lead; Link; Medicine; Metabolic Diseases; Metalloproteins; Metals; Methodology; Microbe; Molecular; Nature; Oral; Organelles; Participant; Physiology; Play; Proteins; Regulation; Research; Research Personnel; Role; Scientist; Series; Signal Transduction; Snow; Structural Biologist; System; Therapeutic; Time; Vermont; Whole Organism; Work; absorption; career; cofactor; graduate student; high standard; human disease; improved; innovation; interest; lectures; meetings; metal metabolism; metalloenzyme; novel diagnostics; novel strategies; pathogen; peer; posters; prognostic; programs; structural biology; symposium; unpublished works

Project Description (Summary/Abstract) The Gordon Research Conference (GRC) series on the “The Cell Biology of Metals” provides a truly outstanding forum for scientific exchanges, presentations and discussions in the emerging field of metals in biology, focusing on the acquisition, distribution, sensing and utilization of metals in proteins, cells and systems from bacteria to humans. This GRC series was initiated in 2005 and in the next cycle was immediately oversubscribed, illustrating that the meeting filled an important niche exploring the molecular mechanisms of metal utilization in proteins, organelles, and whole organisms. This conference has now become a cornerstone of the field and is unique in attacking broad research questions such as how metal cofactors are assembled to how metal ions play roles in metabolic and infectious diseases. The Cell Biology of Metals GRC is held every two years and has consistently attracted more than 140 attendees. The Gordon Research Conference series is internationally renowned for the high-quality, cutting edge nature of its meetings, showcasing unpublished work; the program of the proposed 2017 conference strives to maintain this high standard. The 2017 Cell Biology of Metals GRC will be held on July 23 – 28 at Mount Snow in West Dover, VT. This application describes the preliminary program, which is organized around the theme of “Mechanisms from Microbes to Humans”. Session topics include metals in enzyme function, metalloenzyme strucutres, metal homeostasis, metal sensing and dynamics, metalloprotein biogenesis and signaling, metals in host-pathogen interactions and metals in physiology and disease. The conference will be comprised of keynote presentations, research and poster talks, poster discussions, and informal scientific discussions. This meeting will bring together an outstanding and diverse cadre of molecular and structural biologists, biochemists, geneticists, cell biologists, physiologists and clinicians to interact and brainstorm on new discoveries, ideas and directions in basic and applied research on the cell biology of metals. Given the increase in the number of metabolic and infectious diseases linked to changes in cellular metal homeostasis, this meeting fills a critical niche for investigating the underlying mechanism(s) of these disorders and for brainstorming approaches for novel diagnostics, prognostics, and therapeutics.

项目描述（摘要/摘要） 戈登研究会议 (GRC) 系列“金属细胞生物学”提供了真正的 新兴金属领域科学交流、演讲和讨论的杰出论坛 生物学，专注于蛋白质、细胞和系统中金属的获取、分布、传感和利用 从细菌到人类，这个 GRC 系列于 2005 年启动，并立即在下一个周期中启动。 超额认购，表明该会议填补了探索分子机制的重要空白 该会议现已成为蛋白质、细胞器和整个生物体中金属利用的会议。 该领域的基石，在解决广泛的研究问题（例如金属辅因子如何存在）方面具有独特的优势 组装金属离子如何在代谢和传染病中发挥作用 GRC。 该会议每两年举办一次，一直吸引超过 140 名与会者。 会议系列因其会议的高品质、前沿性而享誉国际， 展示未发表的工作；拟议的 2017 年会议计划力求保持这一高水平 标准。 2017 年金属细胞生物学 GRC 将于 7 月 23 日至 28 日在佛蒙特州西多佛的 Mount Snow 举行。 应用程序描述了初步计划，该计划围绕“来自的机制”的主题组织 微生物对人类”会议主题包括酶功能中的金属、金属酶结构、金属。 稳态、金属传感和动力学、金属蛋白生物合成和信号传导、宿主病原体中的金属 会议将包括生理学和疾病中的相互作用和金属。 本次会议包括演示、研究和海报演讲、海报讨论和非正式科学讨论。 将汇集一支由分子和结构生物学家、生物化学家、 遗传学家、细胞生物学家、生理学家和步兵就新发现、想法和成果进行互动和集思广益 鉴于金属数量的增加，金属细胞生物学的基础和应用研究方向。 代谢和传染病与细胞金属稳态变化有关，这次会议填补了一个关键问题 研究这些疾病的潜在机制和集思广益方法的利基 新的诊断、预后和治疗方法。