2017 Muscle: Excitation-Contraction Coupling Gordon Research Conference and Gordon Research Seminar
2017肌肉:兴奋-收缩耦合戈登研究会议暨戈登研究研讨会
基本信息
- 批准号:9331041
- 负责人:
- 金额:$ 2.3万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-06-01 至 2018-05-31
- 项目状态:已结题
- 来源:
- 关键词:AddendumAgingAreaAtrophicBackBasic ScienceBritish ColumbiaCalcium SignalingCareer MobilityClinicalClinical ResearchClinical TrialsCommunicationCommunitiesCouplingCrystallizationDefectDevelopmentDisciplineDiseaseElementsEnvironmentFunctional disorderGenderGeographic LocationsGoalsGovernmentGrowthHealthHeart DiseasesHumanIndividualIndustrializationInheritedInstitutesInternationalKnowledgeLeadLeadershipMaineMedicalMetabolic DiseasesMetabolismMichiganMolecularMuscleMuscle FatigueMutationMyocardiumMyopathyNeuromuscular DiseasesNeurosciencesOutcomeParticipantPatientsPerformancePostdoctoral FellowProcessQuality of lifeRaceRegulationResearchResearch PersonnelResolutionRoentgen RaysRyanodine Receptor Calcium Release ChannelScientistSkeletal MuscleStructureStudentsSwitzerlandTimeTranslational ResearchTriad Acrylic ResinUniversitiesWorkcareercombateffective therapyexperiencegraduate studentimprovedinnovationinsightmeetingsnew therapeutic targetnewsnovel strategiesnovel therapeuticspostersprogramspublic health relevancesarcopeniaskeletalsuccesssymposium
项目摘要
ABSTRACT
This is a proposal for partial support of the only major national and/or international meeting dedicated to
excitation/contraction coupling and how defects in this critical process underlie muscle disease. The Muscle:
Excitation-Contraction Coupling (ECC) Gordon Research Conference (GRC) will meet from June 4 – June 9,
2017 at Les Diablerets Conference Center in Les Diablerets, Switzerland. The GRC program was developed
by an Executive Organizing Committee consisting of leaders in ECC research including Drs. Héctor H. Valdivia
(University of Michigan), Isabelle Marty (Grenoble Institute of Neurosciences), and Filip Van Petegem
(University of British Columbia). The two overarching objectives of the 2017 Muscle: Excitation-Contraction
Coupling GRC are: Objective 1: To discuss and critically evaluate new breakthroughs regarding the
molecular mechanisms that control ECC and how this process is altered in muscle fatigue, atrophy,
sarcopenia, metabolic disease, and genetically-inherited forms of skeletal and cardiac muscle disease.
Objective 2: To promote visibility and leadership of junior investigators in the field by providing a platform for
students, postdoctoral fellows, and new independent investigators to present their work, as well as to interact
and network with established senior investigators. The 2017 GRC conference will consist of ~30 speakers, ~18
Discussion Leaders, and ~13 poster presentations. Scientific sessions will focus on structural studies of the
ECC apparatus, new insights into the molecular mechanisms and regulation of ECC, identification of new
therapeutic targets, and the development of innovative treatments for muscle fatigue, sarcopenia, and skeletal
and cardiac muscle disorders that adversely impact millions of individuals in the US. For the second time for
this GRC, the meeting will be preceded by a two-day Gordon Research Seminar (GRS) for graduate students
and postdoctoral fellows. In addition, for each session during the GRC a young investigator will be paired with
a senior investigator to serve as Co-Discussion Leaders. Innovative “Poster Flash Sessions” and “This Just In”
speaker slots will be used to highlight late-breaking news. These innovative program elements will also
maximize poster session visibility, as well as to enhance the integration and exposure of promising young
investigators in the field during the GRC. We expect that this conference will attract 150-200 basic and clinical
scientists across all career stages, genders, races, heritages, research disciplines, professional affiliations
(academic, industrial, government), and geographical locations. Our overall aim is to promote: 1) open
dialogue and communication, 2) exposure and career advancement of promising young investigators in the
field, 3) fundamental understanding in the mechanisms of ECC and how defects in this process lead to
compromised skeletal and cardiac muscle performance, and 4) the development of novel and effective
therapies to combat skeletal and cardiac muscle disorders.
抽象的
这是对唯一致力于以下领域的主要国家和/或国际会议的部分支持的提案:
兴奋/收缩耦合以及这一关键过程的缺陷如何导致肌肉疾病:
激励-收缩耦合 (ECC) 戈登研究会议 (GRC) 将于 6 月 4 日至 9 日举行,
2017 年在瑞士莱迪亚布勒雷会议中心制定了 GRC 计划。
由 ECC 研究领域的领导者组成的执行组织委员会,包括 Héctor H. Valdivia 博士
(密歇根大学)、Isabelle Marty(格勒诺布尔神经科学研究所)和 Filip Van Petegem
(不列颠哥伦比亚大学)2017 年肌肉的两个总体目标:兴奋-收缩。
GRC 的耦合是: 目标 1:讨论并批判性地评估有关 GRC 的新突破
控制 ECC 的分子机制以及该过程如何导致肌肉疲劳、萎缩、
肌肉减少症、代谢性疾病以及遗传性骨骼和心肌疾病。
目标 2:通过提供一个平台,提高初级研究人员在该领域的知名度和领导力
学生、博士后研究员和新的独立研究人员展示他们的工作并进行互动
2017 年 GRC 会议将由约 30 名发言人组成,其中约 18 名。
讨论领袖和约 13 场海报展示将重点关注结构研究。
ECC装置,对ECC分子机制和调控的新见解,新发现
目标,以及针对肌肉疲劳、肌肉减少症和骨骼肌减少症的创新治疗方法的开发
和心肌疾病第二次对美国数百万人产生不利影响。
在本次 GRC 会议之前,将为研究生举办为期两天的戈登研究研讨会 (GRS)
此外,GRC 期间的每次会议都会配备一名年轻研究员。
一位高级研究员担任创新的“海报快闪会议”和“This Just In”的领导者。
扬声器时段也将用于突出这些创新的节目元素。
最大限度地提高海报会议的知名度,并增强有前途的年轻人的融入和曝光
GRC 期间,我们预计本次会议将吸引 150-200 名基础和临床研究人员。
各个职业阶段、性别、种族、传统、研究学科、专业背景的科学家
(学术、工业、政府)和地理位置我们的总体目标是促进:1)开放。
对话和交流,2)有前途的年轻研究者在该领域的曝光和职业发展
领域,3)对 ECC 机制的基本了解以及该过程中的缺陷如何导致
骨骼和心肌性能受损,以及 4) 开发新颖有效的药物
对抗骨骼和心肌疾病的疗法。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Hector H Valdivia其他文献
Hector H Valdivia的其他文献
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