Bridging the Childhood Epilepsy Treatment Gap in Northern Nigeria (BRIDGE)

缩小尼日利亚北部儿童癫痫治疗差距 (BRIDGE)

基本信息

批准号：
9406559
负责人：
Muktar Hassan Aliyu
金额：
$ 19.36万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-11 至 2019-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9406559
关键词：
Academic Medical Centers Africa South of the Sahara Age Antiepileptic Agents Area Caring Centers for Disease Control and Prevention (U.S.)Cessation of life Child Child Care Childhood Clinical Research Clinical Trials Clinical Trials Design Communities Community Health Aides Country Data Collection Developed Countries Developing Countries Diagnosis Diagnostic Education Electroencephalogram Environment Epilepsy Evaluation Family Foundations Friends Funding Future HIV Health Health Personnel Health Services Health Services Accessibility Improve Access International Intervention Knowledge Maps Measures Modeling Monitor Morbidity - disease rate Nigeria Nurses Patients Pediatric Neurology Physicians Privatization Qualitative Evaluations Research Resources Risk Rural Seizures Services Sickle Cell Anemia Specialist Stroke prevention Syndrome System Targeted Research Teaching Hospitals Testing Training Training Programs United States National Institutes of Health World Health Organization base care systems clinical care design global health improved improved outcome innovation low and middle-income countries mortality multidisciplinary nervous system disorder novel peer premature rural area satisfaction standard care urban area

项目摘要

Abstract Epilepsy is the most common serious neurological disorder among children worldwide, and approximately 80% of children with epilepsy live in low- and middle-income countries (LMICs), with increased morbidity and increased risk of death. Among children with epilepsy in LMICs, between 67% and 90% are not receiving consistent and appropriate treatment – a phenomena known as the epilepsy treatment gap. The millions of children with epilepsy living in LMICs have not benefited from the advances in epilepsy care over the past half-century, as the models of epilepsy care in rich countries are not easily adapted to the reality of resource- poor sub-Saharan Africa. “Bridging the Childhood Epilepsy Treatment Gap in Northern Nigeria (BRIDGE)” will establish a foundation upon which to perform larger definitive studies and clinical trials of innovative epilepsy care systems and therapies by (a) quantifying and mapping the childhood epilepsy treatment gap in Kano, Nigeria, (b) training, developing, and piloting task-shifted epilepsy care teams to improve epilepsy care access, and (c) developing and piloting innovative epilepsy diagnostic paradigms designed for low-resource environments with limited access to electroencephalograms (EEGs). To accomplish these aims we have assembled a strong multidisciplinary team representing Vanderbilt University Medical Center, Aminu Kano Teaching Hospital in Kano, Nigeria, and the BRIDGE Advisory Board- a multi-disciplinary team of experts focused on bridging the childhood epilepsy treatment gap. BRIDGE, and the clinical trials that will be built upon the BRIDGE foundation, have the potential to close the childhood epilepsy treatment gap in sub-Saharan Africa, and in poor communities around the world.

抽象的癫痫是全世界儿童中最常见的严重神经系统疾病，大约 80% 的癫痫儿童生活在低收入和中等收入国家 (LMIC)，发病率和在中低收入国家中，67% 至 90% 的癫痫儿童没有接受治疗。一致且适当的治疗——这种现象被称为“数以百万计的癫痫治疗差距”。过去，生活在中低收入国家的癫痫儿童并未从癫痫护理的进步中受益半个世纪以来，富裕国家的癫痫护理模式不容易适应资源匮乏的现实。贫穷的撒哈拉以南非洲。 “缩小尼日利亚北部儿童癫痫治疗差距（BRIDGE）”将建立一个基金会在此基础上对创新性癫痫护理系统进行更大规模的确定性研究和临床试验，通过 (a) 量化和绘制尼日利亚卡诺儿童癫痫治疗差距的治疗方法，(b) 培训，发展和试点任务转移的癫痫护理团队，以改善癫痫护理的可及性，以及 (c) 发展并试点专为资源有限的环境而设计的创新癫痫诊断范例为了实现这些目标，我们组建了强大的脑电图（EEG）。代表范德比尔特大学医学中心、阿米努卡诺教学医院的多学科团队尼日利亚卡诺和 BRIDGE 咨询委员会 - 一个多学科专家团队，致力于弥合 BRIDGE 儿童癫痫治疗差距，以及基于 BRIDGE 的临床试验。基金会，有可能缩小撒哈拉以南非洲地区的儿童癫痫治疗差距，以及世界各地的贫困社区。