Vanderbilt-Nigeria Building Research Capacity in HIV and Non-communicable Diseases (NCDs) (V-BRCH)

范德比尔特-尼日利亚建设艾滋病毒和非传染性疾病 (NCD) 研究能力 (V-BRCH)

• 批准号: 10542417
• 负责人: Muktar Hassan Aliyu
• 金额: $ 30.08万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-22 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10542417
• 关键词: Academic Medical Centers; Africa South of the Sahara; Area; Atmosphere; Clinical Trials; Collaborations; Conduct Clinical Trials; Country; Disease; Educational Curriculum; Educational workshop; Epidemiology; Faculty; Foundations; Funding; Grant; HIV; Institution; Learning; Master of Public Health; Master of Science; Mentors; Methodology; Nigeria; Nigerian; Peer Group; Physicians; Pilot Projects; Public Health Education; Research; Research Ethics; Research Institute; Research Personnel; Research Project Grants; Scientist; Site; Staff Development; Sustainable Development; Teaching Hospitals; Training; Training Activity; Training Programs; United States; Universities; Work; Writing; career development; clinical investigation; institutional capacity; meetings; member; peer; programs; research and development; skill acquisition

ABSTRACT The Vanderbilt-Nigeria Building Research Capacity in HIV/Non-communicable Diseases (NCDs) (`V-BRCH') program is a coordinated approach to build the capacity of Nigerian investigators to successfully initiate and implement high-quality clinical trials in HIV-associated NCDs. V-BRCH builds upon long-standing and highly successful collaborations between two leading research institutions in Nigeria and the United States - Aminu Kano Teaching Hospital (AKTH) and Vanderbilt University Medical Center. V-BRCH will solidify an atmosphere of continuous mentoring and skills acquisition for AKTH physician faculty in conducting clinical trials in HIV- associated NCDs via short- and medium- term learning opportunities, paired mentoring arrangements and mentored research projects (Aim 1). We will select three AKTH faculty members per year to attend the highly effective annual 1-month long Vanderbilt Institute for Research Development and Ethics (“VIRDE”) faculty enrichment program in Nashville. We will offer two 2-week, on-site workshops in Nigeria every year for physicians and research staff on HIV-associated NCD epidemiology, clinical trials methodology, and grant writing. We will identify research-oriented junior faculty staff (n=8) at AKTH for focused training in key areas of need and in clinical trials administration and regulatory oversight. Scholars will share best practices and lessons learned through mentoring panels, regular `Works in Progress' meetings, and monthly career development seminars. Competitive seed grants will be provided to mentor-mentee teams (n=10) to promote targeted in-country pilot studies focused on HIV-associated NCDs. For long-term training (Aim 2), we will support enhanced Master of Public Health (MPH) training at Bayero University/AKTH in Nigeria (total: 8 physicians) and Master of Science in Clinical Investigation (MSCI) at Vanderbilt for 2 Nigerian physician scientists. We will build institutional capacity in HIV-associated NCD clinical trials research via short-term regional courses, staff development workshops and MPH curriculum refinement (Aim 3). To take advantage of complementary courses, peer-to-peer group learning and research networking opportunities, V-BRCH will leverage training activities conducted by other FIC-funded training programs in Nigeria and sub-Saharan Africa (South-South collaborative opportunities). V-BRCH represents the culmination of years of collaboration in research and training between Vanderbilt and AKTH and will lay the foundation for sustainable development of clinical trials research focused on HIV-associated NCDs in Nigeria.

抽象的 范德比尔特-尼日利亚建设艾滋病毒/非传染性疾病（NCD）研究能力（“V-BRCH”） 计划是一种协调一致的方法，旨在培养尼日利亚调查人员成功启动和 在与 HIV 相关的非传染性疾病中实施高质量的临床试验 V-BRCH 建立在长期和高度的基础上。 尼日利亚和美国两家领先研究机构之间的成功合作 - Aminu 卡诺教学医院 (AKTH) 和范德比尔特大学医学中心将巩固这种氛围。 AKTH 医师在开展 HIV 临床试验方面的持续指导和技能获取 通过短期和中期学习机会、配对指导安排和 我们每年将选择三名 AKTH 教员来参加高级研究项目（目标 1）。 有效的年度为期 1 个月的范德比尔特研究发展与道德研究所 (“VIRDE”) 教员 我们每年将在尼日利亚举办两次为期两周的现场研讨会。 与艾滋病毒相关的非传染性疾病流行病学、临床试验方法和资助方面的医生和研究人员 我们将在 AKTH 确定以研究为导向的初级教职人员（n = 8），以进行关键领域的集中培训。 学者们将在临床试验管理和监管监督方面分享最佳实践和经验。 通过指导小组、定期的“正在进行中的工作”会议和每月的职业生涯吸取的经验教训 开发研讨会将向导师受训团队（n = 10）提供有竞争力的种子资助，以促进发展。 针对长期培训（目标 2），我们将开展针对艾滋病毒相关非传染性疾病的有针对性的国内试点研究。 支持尼日利亚巴耶罗大学/AKTH 加强公共卫生硕士 (MPH) 培训（总计：8 2 名尼日利亚医生在范德比尔特大学获得临床研究理学硕士学位 (MSCI) 我们将通过短期建设艾滋病相关非传染性疾病临床试验研究的机构能力。 利用区域课程、员工发展研讨会和 MPH 课程完善（目标 3）。 补充课程、同伴小组学习和研究网络机会，V-BRCH 将 利用由 FIC 资助的其他培训项目在尼日利亚和撒哈拉以南非洲开展的培训活动 （南南合作机会）。 范德比尔特大学和 AKTH 之间的研究和培训将为可持续发展奠定基础 尼日利亚的临床试验研究重点是与艾滋病毒相关的非传染性疾病。