UT Southwestern NCI National Clinical Trials Network Lead Academic Site - U10

UT 西南 NCI 国家临床试验网络主要学术网站 - U10

基本信息

批准号：
9206742
负责人：
JOAN H SCHILLER
金额：
$ 5万
依托单位：
UT SOUTHWESTERN MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-04-09 至 2019-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9206742
关键词：
Academic Medical Centers Adult African American American Cancer Society American College of Radiology Imaging Network American College of Surgeons Oncology Group American Society of Clinical Oncology Area Basic Science Breast Cancer Center Chest Clinic Clinical Clinical Research Clinical Trials Collaborations Country Department chair Discipline Disease Eastern Cooperative Oncology Group Enrollment Ethics Ethnic Origin Faculty Funding Grant Gynecologic Oncology Group Head and neck structure Health Hematology Heme Hispanics Image Institution Lead Leadership Lung Magnetic Resonance Imaging Malignant neoplasm of lung Medical center Mentors NCI-Designated Cancer Center National Clinical Trials Network National Surgical Adjuvant Breast and Bowel Project Oncology Group Patients Physician Executives Population Positioning Attribute Positron-Emission Tomography Principal Investigator Publications Radiation Oncology Radiation Therapy Oncology Group Recording of previous events Recruitment Activity Research Research Personnel Role Services Site Southwest Oncology Group Texas Therapeutic Trials Translating Translational Research Universities abstracting cancer diagnosis career development drug discovery ethnic minority population innovation medical schools member metropolitan multidisciplinary neuro-oncology oncology patient population programs quantitative imaging racial and ethnic racial minority

项目摘要

DESCRIPTION (provided by applicant): The University of Texas Southwestern Medical Center (UTSW) has a history of leadership, translational research, and accrual to cooperative group trials. The PI of this grant is Dr. Joan Schiller, chief of the Division of Heme/Oncology and Deputy Director of the Simmons Cancer Center (SCC), former Chair of ECOG's Thoracic Committee and currently PI of UTSW's main institution ECOG grant. Co-investigators include Dr. Hak Choy, Chair of UTSW's Department of Radiation Oncology, Vice Chair for Disease Sites in RTOG, and former Chair of RTOG's Thoracic Committee; Dr. David Miller, member of the GOG Board of Directors and Chair of the Uterine Corpus Committee; Dr. Marilyn Leitch, member of the Executive Committee of ACOSOG, and Dr. Phil Evans, immediate past president of the American Cancer Society, who was one of the founding members of the ACRIN Breast committee, and served as the principal investigator at UTSW for ACRIN sponsored trials. In 2012, UTSW enrolled 105 patients on adult co-operative group trials. Since 2006, UTSW faculty have investigated or co-investigated 96 co-operative group publications and 85 abstracts, and have chaired, co-chaired, or served as cooperative committee chair on 34 cooperative group trials. UTSW is also a site for the NCI Centers Quantitative imaging Excellence. UTSW is the only academic medical center and medical school in the Dallas/Ft. Worth (DFW) Metroplex, the fourth largest metropolitan area in the country, and is the only NCI designated Cancer Center in north Texas. UTSW also has a strong clinical and transitional research program and drug discovery program; a SPORE in lung cancer; an Advanced Imaging Research Center; and has access to a diverse ethnic and racial population. In the DFW Metroplex, roughly 10.3% of the populations with a cancer diagnosis are Hispanic, and 14.1% are African American; in 2012, 29.6% of SCC patients going on co-operative group clinical studies were of Hispanic ethnicity, and 13.6% were of African American ancestry. The specific aims of the UTSW UIO are to contribute to and promote: (1) The NCTN by enrolling patients with diverse ethnic and racial background on therapeutic and non-therapeutic trials; (2) The scientific direction of the NCTN by bringing the basic, translational, and imaging research conducted at UTSW into hypothesis driven clinical trials. (3) Multidisciplinary efforts and collaboration across multiple disciplinesand multiple cooperative groups; (4) Service in leadership roles by chairing and co-chairing clinical trials and committees, and by participating in NCI activities and initiatives; and (5) The career development of junior faculty.

描述（由申请人提供）：德克萨斯大学西南医学中心 (UTSW) 在领导力、转化研究和合作团体试验方面有着悠久的历史。此项资助的 PI 是血红素/肿瘤科主任 Joan Schiller 博士和西蒙斯癌症中心 (SCC) 副主任、ECOG 胸科委员会前主席，现任 UTSW 主要机构 ECOG 资助项目的 PI。联合研究人员包括 Hak Choy 博士，他是 UTSW 放射肿瘤学系主任、RTOG 疾病中心副主席、RTOG 胸部委员会前主席； David Miller 博士，GOG 董事会成员、子宫体委员会主席； ACOSOG 执行委员会成员 Marilyn Leitch 博士和美国癌症协会前任主席 Phil Evans 博士（ACRIN 乳腺委员会创始成员之一，并担任 UTSW 的首席研究员） ACRIN 赞助了试验。 2012 年，UTSW 招募了 105 名患者参加成人合作组试验。自 2006 年以来，UTSW 教师已调查或共同调查了 96 份合作小组出版物和 85 份摘要，并在 34 项合作小组试验中担任主席、联合主席或担任合作委员会主席。 UTSW 也是 NCI 中心定量成像卓越中心的网站。 UTSW 是达拉斯/英尺唯一的学术医疗中心和医学院。沃斯 (DFW) 大都会区是美国第四大都市区，也是德克萨斯州北部唯一一家 NCI 指定的癌症中心。 UTSW 还拥有强大的临床和过渡研究项目以及药物发现项目；肺癌中的孢子；先进成像研究中心；并且可以接触到不同民族和种族的人口。在 DFW Metroplex，大约 10.3% 的癌症诊断人群是西班牙裔，14.1% 是非裔美国人； 2012年，参加合作小组临床研究的SCC患者中有29.6%是西班牙裔，13.6%是非裔美国人。 UTSW UIO 的具体目标是促进和促进： (1) NCTN，招募具有不同民族和种族背景的患者参加治疗和非治疗试验； (2) NCTN 的科学方向，将 UTSW 进行的基础、转化和影像研究纳入假设驱动的临床试验。（3）多学科的努力和跨学科、多个合作群体的协作； (4) 通过主持和共同主持临床试验和委员会以及参与 NCI 活动和倡议来发挥领导作用； (5)青年教师的职业发展。