TRIO NRSA Training Core
TRIO NRSA 培训核心
基本信息
- 批准号:10889668
- 负责人:
- 金额:$ 74.18万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-09-01 至 2028-06-30
- 项目状态:未结题
- 来源:
- 关键词:Admission activityAdoptionAgricultureBasic ScienceBiomedical ResearchBiotechnologyClinicalClinical ResearchClinical SciencesClinical and Translational Science AwardsCommunitiesDevelopmentDisparityEmerging TechnologiesEnvironmentFacultyFosteringFutureHematologyHistorically Black Colleges and UniversitiesInstitutionKidneyLeadershipLearningLongevityMentorsMissionNational Research Service AwardsNorth CarolinaPostdoctoral FellowProcessProgram EvaluationPublic HealthQualifyingResearchResearch PersonnelResearch TrainingScienceTNFSF15 geneTechnologyTimeTrainingTraining ProgramsTraining and InfrastructureTranslational ResearchUniversitiescareerexperienceforesthigh schoolimprovedinnovationmedical specialtiesmultidisciplinarynext generationoutreachpatient populationpre-doctoralprogramsrecruitscale upskill acquisitionskillssocialsupport networksynergismtoolurologic
项目摘要
Today’s incipient and early career trainees in Kidney, Urologic, Hematologic (KUH) fields require training
within environments richly populated by accomplished team-science researchers and adept, committed mentors.
Trainees must learn sophisticated research tools while simultaneously completing didactic coursework and
developing professional development skills. Coordinating these efforts will enable scale-up of high-impact
practices to remove the daunting academic and social barriers that have caused persistent disparities among
KUH clinicians and researchers, and the direct gains of this training program will be realized most by the KUH
patient populations we serve. Training the next generation of KUH researchers requires institutions and mentors
to synergistically engage in both research and training. We have brought together KUH researchers at 3 leading
North Carolina (NC) biomedical research universities: University of North Carolina-Chapel Hill, Wake Forest
University, and Duke University, as well as from 3 Historically Black Colleges and Universities, NC Agricultural
& Technical State University, Winston-Salem State University and NC Central University. Together, this forms
the NC KUH TRIO (Training, Research, Innovation, Outreach, or TRIO) U2C/TL1 Research Training Program.
The TRIO Training Core has 3 objectives: 1) provide didactics and hands-on experience in rigorous
basic/translational and clinical sciences research; 2) conduct research that includes adoption of emerging
technologies and builds on the cross-disciplinary and cross-institutional team science across the KUH mission;
and 3) establishes and nourishes a community of scholars that expands and sustains diversity in KUH research.
Multidisciplinary and team research skills will be developed under the Professional Development Core in
conjunction with Clinical and Translational Science Award (CTSA) programs. A connected community of TRIO
scholars, that spans from high school to early faculty, will be built and supported by the Networking Core.
Qualified and motivated TRIO mentors will train both pre- and post-doctoral trainees across broad, highly
relevant KUH scientific specialties that span basic/translational, clinical, and technology arenas. Emerging
mentors will mature to assure future leadership and longevity of the program. TRIO will exploit existing multi-institutional training infrastructures and programs in biotechnology, public health, translational science, and
clinical research. A robust and transparent admissions process with targeted recruitment will foster diversity, and
rigorous program evaluation will allow real-time improvement in serving the needs of our KUH trainees. The
integrated TRIO program will leverage cross-institutional synergies and provide cohesive programming to train
the next generation leaders in multidisciplinary and team KUH-relevant research.
当今的肾脏,泌尿科,血液学(KUH)领域的初期和早期职业学员需要培训
在有成就的团队科学研究人员和熟练的指导者熟练的环境中。
学员必须学习复杂的研究工具,同时完成教学课程和
发展专业发展技能。协调这些努力将使高影响力扩大
消除艰巨的学术和社会障碍的实践,这些障碍在
KUH临床医生和研究人员,以及该培训计划的直接收益将由Kuh实现
我们服务的患者人群。培训下一代KUH研究人员需要机构和导师
协同参与研究和培训。我们在3个领先
北卡罗来纳州(NC)生物医学研究大学:北卡罗来纳大学 - 教堂山,维克森林
大学和杜克大学以及北卡罗来纳州的3所历史悠久的黑人大学和大学
&技术州立大学,温斯顿 - 塞勒姆州立大学和北卡罗来纳州中央大学。在一起,这种形式
NC KUH三重奏(培训,研究,创新,外展或三重奏)U2C/TL1研究培训计划。
三重奏训练核心有3个目标:1)提供严格的教学和动手经验
基础/转化和临床科学研究; 2)进行包括采用新兴的研究
技术和建立在KUH任务中的跨学科和跨机构团队科学的基础上;
3)建立并滋养了一个学者社区,这些学者在KUH研究中扩大和自杀的多样性。
多学科和团队研究技能将在专业发展核心下发展
与临床和转化科学奖(CTSA)计划的联系。三人联网社区
从高中到早期教师的学者将由网络核心建造和支持。
合格和积极进取的三重奏导师将培训前后学员的宽广,高度
相关的KUH科学专业,涵盖基本/转化,临床和技术领域。新兴
导师将成熟,以确保该计划的未来领导能力和寿命。三人将利用生物技术,公共卫生,转化科学和
临床研究。有针对性招聘的强大而透明的入学过程将促进多样性,并
严格的计划评估将允许实时改善我们的KUH学员的需求。
综合三重奏计划将利用跨机构的协同作用,并提供凝聚力的编程来培训
多学科和团队与KUH相关的研究领导者的下一代领导者。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Graca Duarte Almeida-Porada', 18)}}的其他基金
Targeted conditioning to maximize prenatal HSC engraftment for SCD
针对性调节以最大限度地提高 SCD 的产前 HSC 植入
- 批准号:
10654382 - 财政年份:2023
- 资助金额:
$ 74.18万 - 项目类别:
Using human liver tissue equivalents to optimize AAV-mediated GT and better define age-related clinical risks
使用人类肝脏组织等效物优化 AAV 介导的 GT 并更好地定义与年龄相关的临床风险
- 批准号:
10567919 - 财政年份:2023
- 资助金额:
$ 74.18万 - 项目类别:
Defining the therapeutic efficacy, tolerogenic potential, and genotoxicity of liver-targeted AAV gene therapy for hemophilia A
定义肝脏靶向 AAV 基因疗法治疗血友病 A 的疗效、耐受潜力和遗传毒性
- 批准号:
10704568 - 财政年份:2022
- 资助金额:
$ 74.18万 - 项目类别:
cGMP Manufacture Of FVIII-Expressing Placental Cells For Hemophilia A
用于治疗 A 型血友病的表达 FVIII 的胎盘细胞的 cGMP 生产
- 批准号:
9811291 - 财政年份:2019
- 资助金额:
$ 74.18万 - 项目类别:
Prenatal Cell and Gene Therapy for Hemophilia A
A 型血友病的产前细胞和基因治疗
- 批准号:
10014648 - 财政年份:2017
- 资助金额:
$ 74.18万 - 项目类别:
Prenatal Cell and Gene Therapy for Hemophilia A
A 型血友病的产前细胞和基因治疗
- 批准号:
9751959 - 财政年份:2017
- 资助金额:
$ 74.18万 - 项目类别:
Postnatal Cell-Based Therapies for Hemophilia A
A 型血友病的产后细胞疗法
- 批准号:
9336336 - 财政年份:2016
- 资助金额:
$ 74.18万 - 项目类别:
Postnatal Cell-Based Therapies for Hemophilia A
A 型血友病的产后细胞疗法
- 批准号:
9186030 - 财政年份:2016
- 资助金额:
$ 74.18万 - 项目类别:
Cord Blood Expansion Inside a Bioengineered Liver
生物工程肝脏内的脐带血扩增
- 批准号:
8703780 - 财政年份:2013
- 资助金额:
$ 74.18万 - 项目类别:
Cord Blood Expansion Inside a Bioengineered Liver
生物工程肝脏内的脐带血扩增
- 批准号:
8466559 - 财政年份:2013
- 资助金额:
$ 74.18万 - 项目类别:
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