Northern New England Clinical and Translational Research Network - N3C Initiative

新英格兰北部临床和转化研究网络 - N3C Initiative

• 批准号: 10887984
• 负责人: CLIFFORD JAMES ROSEN
• 金额: $ 34.83万
• 依托单位: MAINEHEALTH
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-03 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10887984
• 关键词: 2019-nCoV; Acceleration; Address; Administrative Supplement; Area; Artificial Intelligence; Big Data; COVID-19; COVID-19 impact; COVID-19 pandemic; COVID-19 patient; COVID-19 treatment; Cardiovascular Diseases; Clinical Data; Clinical Research; Collaborations; Communities; Community Health; Contracts; Coupled; Cultural Diversity; Data; Databases; Dedications; Deposition; Development; Diabetes Mellitus; Disease; Education; Education and Outreach; Educational Activities; Food; Funding; Goals; Health; Immigrant; Infrastructure; Institution; Leadership; Link; Machine Learning; Maine; Malignant Neoplasms; Manuscripts; Minority; National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; Native Americans; New England; New Hampshire; Obesity; Patients; Population; Refugees; Registries; Reporting; Request for Applications; Research; Research Infrastructure; Research Personnel; Resources; Rural; Rural Health; Sampling; Science; Scientist; Secure; Substance Use Disorder; System; Techniques; Training and Education; Translational Research; Tribes; Underserved Population; United States National Institutes of Health; Universities; Variant; Vermont; Viral; Work; cloud based; cohort; community based research; computer infrastructure; data infrastructure; data registry; data warehouse; effective therapy; experience; health disparity; human old age (65+); improved; innovation; interest; investigator training; member; operation; outcome disparities; pandemic disease; practice-based research network; primary care practice; rural dwellers; rurality

ABSTRACT The National Covid Cohort Collaborative (N3C), sponsored by the National Center for Advancing Translational Sciences (NCATS) and the National Center for Data to Health (Cd2H) have created a centralized national database on a cloud-based analytic platform for scientists to use to study COVID-19, identify potential treatments, and report on outcomes and health disparities. It is a partnership among more than 80 institutions that is funded by the National Institutes of Health. Collaborators have contributed data so far on nearly 8 million COVID-19 positive patients, as well as several million control patients. The collaborators use the clinical data on these patients to answer critical research questions to address the pandemic and accelerate development of effective treatments. The Northern New England Clinical and Translational Research Network has actively participated in N3C for over 3 years and is submitting this administrative supplement to allow for our continued participation for another year. This application details our past accomplishments and describes our planned work for the coming year.

抽象的 国家 Covid 队列协作 (N3C)，由国家推进转化中心赞助 科学 (NCATS) 和国家健康数据中心 (Cd2H) 创建了一个集中的国家 基于云的分析平台上的数据库，供科学家用来研究 COVID-19、识别潜力 治疗，并报告结果和健康差异。它是 80 多家机构之间的合作伙伴关系 由美国国立卫生研究院资助。迄今为止，合作者已贡献了近 800 万条数据 COVID-19 阳性患者以及数百万对照患者。合作者使用临床数据 让这些患者回答关键的研究问题，以应对这一流行病并加速发展 的有效治疗方法。新英格兰北部临床和转化研究网络积极 参加 N3C 已超过 3 年，现提交此行政补充文件，以便我们能够继续 再参加一年。该应用程序详细介绍了我们过去的成就并描述了我们的计划 来年的工作。

项目成果

Exploring Parent Experience of Communication About Therapeutic Hypothermia in the Neonatal Intensive Care Unit.

• DOI: 10.1097/anc.0000000000000473
• 发表时间: 2018-04
• 期刊: Advances in neonatal care : official journal of the National Association of Neonatal Nurses
• 作者: Craig AK;Gerwin R;Bainter J;Evans S;James C
• 通讯作者: James C

Harm Reduction Services to Prevent and Treat Infectious Diseases in People Who Use Drugs.

• DOI: 10.1016/j.idc.2020.06.013
• 发表时间: 2020-09
• 期刊: Infectious disease clinics of North America
• 影响因子: 4.4
• 作者: Thakarar K;Nenninger K;Agmas W
• 通讯作者: Agmas W

Comparative effectiveness of denosumab, teriparatide, and zoledronic acid among frail older adults: a retrospective cohort study.

• DOI: 10.1007/s00198-020-05732-2
• 发表时间: 2021-03
• 期刊: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
• 作者: Zullo AR;Lee Y;Lary C;Daiello LA;Kiel DP;Berry SD
• 通讯作者: Berry SD

A Review of Public Health Training Needs Assessment Approaches: Opportunities to Move Forward.

• DOI: 10.1097/phh.0000000000000774
• 发表时间: 2018
• 期刊: Journal of public health management and practice : JPHMP
• 作者: Joly BM;Coronado F;Bickford BC;Leider JP;Alford A;McKeever J;Harper E
• 通讯作者: Harper E

The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis.

• DOI: 10.1002/jcp.25976
• 发表时间: 2018-03
• 期刊: Journal of cellular physiology
• 影响因子: 5.6
• 作者: Fairfield H;Falank C;Harris E;Demambro V;McDonald M;Pettitt JA;Mohanty ST;Croucher P;Kramer I;Kneissel M;Rosen CJ;Reagan MR
• 通讯作者: Reagan MR