NIDDK Extramural Digital Pathology Repository System (HALO LINK)

NIDDK 校外数字病理学存储系统 (HALO LINK)

• 批准号: 10884865
• 负责人: NA NA
• 金额: $ 1.66万
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10884865
• 关键词: Archives; Artificial Intelligence; Clinical; Clinical Research; Computer-Assisted Image Analysis; Data Set; Diabetes Mellitus; Digestive System Disorders; Disease; Extramural Activities; Future; Goals; Investigation; Kidney Diseases; Machine Learning; Metadata; Mining; Molecular; National Institute of Diabetes and Digestive and Kidney Diseases; Research; Standardization; System; Validation; clinical research site; computerized data processing; diagnostic criteria; digital; digital pathology; feature detection; new technology; online repository; programs; repository; whole slide imaging

In recent years, new technology and data processing capabilities have removed barriers to integration of molecular and histopathological data sets. Several clinical research networks across the National Institute of Diabetes, Digestive and Kidney Diseases extramural programs have put Digital Pathology Repositories (DPRs) into place with digital whole slide images (WSI) available to support standardization of classical diagnostic criteria across clinical sites. A developing line of investigation is the “mining” of these digital sets to identify features which correlate with disease. Computer assisted-image analysis for feature detection and feature recognition are key components of such investigation. The Centralized NIDDK Digital Pathology Repository will serve as an online repository to facilitate standardized archiving of WSI with the goal of providing controlled access for standardization, discovery and validation research efforts.

近年来，新技术和数据处理能力消除了分子和组织病理学数据集整合的障碍，国家糖尿病、消化和肾脏疾病研究所外部项目的几个临床研究网络已经建立了数字病理学存储库（DPR）。数字全切片图像（WSI）可用于支持跨临床站点的经典诊断标准的标准化，一个正在发展的研究方向是“挖掘”这些数字集以识别与疾病相关的特征。特征检测和特征识别是此类研究的关键组成部分，集中式 NIDDK 数字病理学存储库将作为一个在线存储库，促进 WSI 的标准化存档，旨在为标准化、发现和验证研究工作提供受控访问。