Oil and Gas as Drivers of Climate Change and Health: Developing unique resources to investigate multi-level and diverse effects of exposure to oil and gas wells

石油和天然气作为气候变化和健康的驱动因素：开发独特的资源来调查接触石油和天然气井的多层次和多样化的影响

• 批准号: 10839157
• 负责人: James V Lacey
• 金额: $ 65.06万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10839157
• 关键词: Acceleration; Address; Adult; Affect; Asthma; California; Carcinogens; Censuses; Clinical; Cohort Studies; Complex; Computer software; Data; Data Commons; Data Linkages; Databases; Disease; Education; Emergency department visit; Energy-Generating Resources; Environment; Ethnic Origin; Event; Exposure to; Flare; Future; Gases; Green space; Health; Home; Hospitalization; Human; Immune System Diseases; Income; Individual; Industry; Liver diseases; Location; Malignant Neoplasms; Measures; Neighborhoods; Oils; Participant; Patient Self-Report; Pattern; Persons; Play; Population; Population Density; Population Sciences; Positioning Attribute; Production; Race; Recording of previous events; Research; Research Personnel; Research Priority; Resources; Risk; Schools; Secure; Services; Site; Socioeconomic Status; Subgroup; Surveys; System; Time; Toxin; Vulnerable Populations; Woman; Work; Workplace; World Health; anticancer research; climate change; climate impact; climate-related health; cloud based; cohort; data access; data integration; data resource; data visualization; exposed human population; follow-up; greenhouse gases; human disease; improved; interest; large scale data; mortality; nervous system disorder; novel; pollutant; prospective; respiratory; study population; teacher; tool; user-friendly; walkability

PROJECT SUMMARY / ABSTRACT The oil and gas industry generates half of all global greenhouse gasses. On the ground, local oil and gas production creates myriad exposures that can increase risks of developing asthma and cancer, as well as liver, immune, and neurologic diseases. Millions of California residents live, work, and play near active oil and gas wells because the State does not require any minimum distance between those wells & schools, homes, parks, or workplaces. Exposure to oil & gas wells is complex and dynamic, but few studies include the breadth and depth of data necessary to fully assess contemporary health effects or understand future changes. The California Teachers Study (CTS) is a prospective observational cohort that has followed N=133,477 adult women, almost all of whom live in California, continuously since 1995-1996. We propose to create detailed, individual-level data on CTS participants' exposure to oil and gas wells during CTS follow-up. First, we will use detailed data on all oil and gas wells in California from the California Department of Conservation Geologic Energy Management Division (CalGEM) well statewide tracking system (WellSTAR) and from Enverus, a commercial service that maintains a national database of all oil and gas well drilling, system to identify who was exposed to oil and gas well sites. We will create time-dependent exposure metrics that capture individuals' exposures to active, idle, and capped wells, by time, distance, and production volume, as well as flaring events. Second, we will integrate those exposures with other neighborhood-level measures of socioeconomic status (from the US Census Bureau) and environment burden (from CalEnviroScreen). Third, we will characterize the real-world exposure distribution of oil and gas wells and production over time and across CTS participant subgroups of interest. These summary data and data visualizations will provide the specific and detailed data researchers need to accelerate their planning and future research. We will also conduct a proof- of-concept project by comparing respiratory-related emergency department visit patterns among participants who were exposed vs. unexposed to oil and gas wells. The CTS is an ideal setting in which to generate these novel data that can accelerate research on climate change. All of these data and resources will be openly available to researchers everywhere via the secure, user-friendly, and cloud-based CTS Researcher Platform. These data will enable a broad range of research that can quantify the effects of oil and gas production exposure on numerous disease endpoints; evaluate the potential interactions between these exposures and other aspects of the built and natural environment; and assess the potential impacts of past and future changes in exposure, such as when well production is paused or permanently ended. These data will position the CTS to support a broad range of hypothesis-driven population-sciences research on how oil and gas production affects human health and influences the impact of climate change on human health.

项目摘要 /摘要 石油和天然气行业产生了全球所有温室气体的一半。在地面上，当地的石油和天然气 生产产生无数的暴露，可以增加患哮喘和癌症以及肝脏的风险 免疫和神经疾病。数以百万计的加利福尼亚居民在活跃的石油和天然气附近生活，工作和玩耍 井，因为该州不需要这些井和学校，房屋，公园， 或工作场所。暴露于油气井是复杂而动态的，但是很少有研究包括广度和 充分评估当代健康影响或了解未来变化所需的数据深度。这 加利福尼亚教师研究（CTS）是一个前瞻性观察队列，遵循n = 133,477成人 自1995 - 1996年以来，妇女几乎所有人都住在加利福尼亚。我们建议创建详细的 CTS随访期间，有关CTS参与者对石油和天然气井的个人级别数据。首先，我们将使用 加利福尼亚保护部地质学部的加利福尼亚州所有石油和天然气井的详细数据 能源管理部（CALGEM）井在全州范围的跟踪系统（WellStar）和Enverus， 维护所有油气井钻井的国家数据库的商业服务，系统以确定谁 暴露于石油和天然气井站点。我们将创建依赖时间的暴露指标，以捕获个人 按时间，距离和生产量以及燃烧 事件。其次，我们将将这些暴露与其他社区级别的社会经济措施相结合 地位（来自美国人口普查局）和环境负担（来自Calenviroscreen）。第三，我们会的 表征油气井的现实暴露分布以及随着时间的推移以及CTS的生产 参与者感兴趣的亚组。这些摘要数据和数据可视化将提供特定和 详细的数据研究人员需要加速他们的计划和未来研究。我们还将进行证明 - 通过比较参与者的呼吸有关的急诊科访问模式，以概念项目的项目进行比较 暴露于油气井的暴露与未暴露的人。 CTS是生成这些的理想环境 可以加速气候变化研究的新型数据。所有这些数据和资源将公开 通过安全，用户友好和基于云的CTS研究人员平台可供各地的研究人员使用。 这些数据将实现广泛的研究，可以量化石油和天然气的影响 在众多疾病终点接触；评估这些暴露与 建筑和自然环境的其他方面；并评估过去和未来的潜在影响 暴露的变化，例如何时暂停生产或永久结束。这些数据将定位 CTS支持大量假设驱动的人口研究的研究 生产会影响人类健康，并影响气候变化对人类健康的影响。

项目成果

A Rare Cancer Opportunity.

罕见的癌症机会。

• DOI: 10.1158/1055-9965.epi-21-0427
• 发表时间: 2021
• 期刊: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
• 作者: LaceyJr,JamesV

Zhong et al. Respond to "There's No Place Like Home".

钟等人。

• DOI: 10.1093/aje/kwac085
• 发表时间: 2022
• 期刊: American journal of epidemiology
• 影响因子: 5
• 作者: Zhong,Charlie;Franklin,Meredith;Wang,SophiaS;Longcore,Travis
• 通讯作者: Longcore,Travis