FDA Vet-LIRN Capacity-Building of Ohio ADDL to support bacterial identification of foodborne pathogens

FDA Vet-LIRN 俄亥俄州 ADDL 能力建设支持食源性病原体的细菌鉴定

• 批准号: 10829120
• 负责人: Melanie Prarat
• 金额: $ 5万
• 依托单位: OHIO STATE DEPARTMENT OF AGRICULTURE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2024-08-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10829120
• 关键词: FDA; Vet; LIRN; Capacity; Building

This proposal from the Ohio Department of Agriculture (ODA) is in response to Funding Opportunity Announcement (FOA) PAR-18-604 from the Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM) Veterinary Laboratory Investigation and Response Network (Vet-LIRN). This proposal from ODA’s Animal Disease Diagnostic Laboratory (ADDL) addresses the following key project areas: 1. Purchase of equipment needed to improve diagnostic capacity for Vet-LIRN case investigations of foodborne pathogens. a. We are requesting funds to support to the purchase of a Bruker MALDI Biotyper® Sirius RUO System for bacterial identification. 2. Conduct increased testing in response to a new need identified by the VPO. a. MALDI-TOF technology allows for high throughput identification of bacterial isolates to reduce turnaround time of bacterial culture and isolation. Additionally, participation in additional projects such as method development and/or method validation/improvement and matrix extension work as determined by the VPO may be included in the capacity-building funds. This proposal will maintain the capacity of our laboratory to conduct molecular diagnostic testing for high-throughput sample processing capability and data analysis by maintaining active service contracts to reduce any delays in testing due to equipment malfunctions or needed repairs.

俄亥俄州农业部 (ODA) 的这项提案是对资金的回应 美国食品和药物管理局的机会公告 (FOA) PAR-18-604 (FDA) 兽医中心 (CVM) 兽医实验室调查和 响应网络（Vet-LIRN）。 ODA 动物疾病诊断实验室 (ADDL) 的这项提案解决了 以下重点项目领域： 1. 购买提高 Vet-LIRN 诊断能力所需的设备 食源性病原体病例调查。 a. 我们正在请求资金支持购买布鲁克 MALDI Biotyper® Sirius RUO 细菌鉴定系统。 2. 进行更多的测试以响应确定的新需求 副总裁。 MALDI-TOF 技术可实现高通量识别 细菌分离株以减少细菌的周转时间 文化和隔离。 此外，参与其他项目，例如方法开发和/或 由公益创投机构 (VPO) 确定的方法验证/改进和矩阵扩展工作 该提案可能会纳入能力建设资金中。 我们实验室对高通量样品进行分子诊断检测 通过维护有效的服务合同来处理能力和数据分析 减少由于设备故障或需要维修而造成的测试延误。