Interpersonal Stress, Social Media, and Risk for Adolescent Suicidal Thoughts and Behaviors

人际压力、社交媒体以及青少年自杀想法和行为的风险

• 批准号: 10815112
• 负责人: RANDY PATRICK AUERBACH
• 金额: $ 95.72万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-14 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10815112
• 关键词: 17 year old; Address; Adolescent; Age; Amygdaloid structure; Anterior; Biological; Biological Markers; Biological Process; Buffers; Cause of Death; Characteristics; Chronic; Clinical; Clinical assessments; Coupling; Data; Development; Emergency department visit; Enrollment; Evaluation; Event; Exhibits; Exposure to; Feedback; Feeling suicidal; Functional Magnetic Resonance Imaging; Future; Generations; Goals; Hair; Hate; Hospitalization; Hydrocortisone; Insula of Reil; Interruption; Interview; Lead; Life; Link; Measures; Mediating; Mental disorders; Methods; Natural Language Processing; Pathway interactions; Patient Self-Report; Persons; Physiological; Physiological Processes; Predisposition; Process; Public Health; Recording of previous events; Reporting; Research; Risk; Risk Behaviors; Risk Factors; Sampling; Severities; Social Environment; Social Network; Social Processes; Social support; Speech; Stress; Suicide; Suicide attempt; Testing; Time; Victimization; Violence; Youth; adolescent suicide; digital; experience; follow up assessment; high risk; hypothalamic-pituitary-adrenal axis; ideation; innovation; neural; neural correlate; neural network; novel; peer; preventive intervention; recruit; response; social; social capital; social media; suicidal; suicidal adolescent; suicidal behavior; suicidal risk; suicide rate; temporal measurement; theories

Project Summary Over the past 15 years, suicide rates among adolescents have increased ~60%. Recently, problematic social media use has been linked to the emergence of suicidal thoughts and behaviors (STB), perhaps reflecting greater interpersonal stress exposure. Understanding the type, timing, and severity of interpersonal stress exposure is critical to understand STB risk, which requires carefully characterizing exposures present in their digital lives through a deep interrogation of real-time interactions within social media. In line with the Stress Generation Framework, adolescents experiencing psychiatric disorders possess characteristics that increase the occurrence of interpersonal stress, which may include negative social media exposures. Accordingly, this project will identify social neural susceptibilities that may increase the occurrence of negative social media exposures and examine physiological processes that are impacted by negative social media exposures over time. Our study will include adolescents ages 14-17 (N=300), which will be oversampled for youth at high risk for suicide (n=200), defined as STB in the past 3 months and/or a past-year suicide attempt. Additionally, we will recruit adolescents with psychiatric disorders but without a lifetime history of STB (n=100), providing an opportunity to identify biological markers and temporally refined social media exposures that characterize risk for STB as opposed to identifying risk factors that associate with psychiatric disorders more broadly. Comprehensive clinical assessments will be completed at baseline, and additionally, we will probe past-year user-generated content to assess dynamic changes in negative exposures to characterize core interpersonal processes across social media platforms, including: (a) online victimization (e.g., harassment, hate speech), (b) reduced social capital (e.g., reduced social network size), and (c) reduced social support (e.g., reduced engagement, reciprocity of messaging). We also will collect baseline fMRI neural responses characterizing social processes and assess chronic HPA axis activity. At the 2-, 4-, and 6-month follow-up assessments, interviews, social media data, HPA axis activity, and self-reports will be re-assessed. The overarching goals is to examine the relationship between biological processes and social media exposures, particularly with regards to elucidating suicide risk. First, we will test whether social neural network alterations increase susceptibility to negative social media exposures. Second, we will test whether negative social media exposures negatively impact HPA axis activity. Last, we will test whether negative social media exposures, social neural alterations, HPA axis activity, and their interactions lead to the emergence of suicide events (i.e., actual, interrupted, or aborted attempts; active suicidal ideation with method, intent, or plan; emergency department visits or psychiatric hospitalizations for STB). Through this comprehensive approach, we will address a critical public health initiative by identifying those who are susceptible to negative social media exposures, and providing actionable markers to reduce the needless loss of life among young people.

项目摘要 在过去的15年中，青少年的自杀率增加了约60％。最近，有问题 社交媒体使用与自杀思想和行为的出现有关（STB），也许反映了 更大的人际压力暴露。了解人际压力的类型，时机和严重性 暴露对了解STB风险至关重要，这需要仔细表征其中存在的暴露 数字通过对社交媒体中实时互动的深入询问来生活。与压力一致 一代框架，经历精神疾病的青少年具有增加的特征 人际压力的发生，可能包括负面的社交媒体暴露。因此，这个 项目将确定可能增加负面社交媒体发生的社会神经敏感性 暴露并检查受负面社交媒体暴露影响的生理过程 时间。我们的研究将包括14-17岁（n = 300）的青少年，这将为高风险的年轻人过采样 自杀（n = 200），在过去3个月中定义为STB和/或过去一年的自杀企图。此外，我们会的 招募精神疾病的青少年，但没有STB的终身历史（n = 100），提供了 识别生物学标记和时间精致的社交媒体暴露的机会，以表征风险 对于STB而不是确定与精神疾病相关的危险因素。 全面的临床评估将在基线完成，此外，我们将探测过去的一年 用户生成的内容以评估负面暴露的动态变化以表征核心人际关系 跨社交媒体平台的过程，包括：（a）在线受害（例如骚扰，仇恨言论），（b） 减少社会资本（例如，社交网络规模降低）和（c）减少社会支持（例如，减少 参与，消息的互惠）。我们还将收集表征社会的基线fMRI神经反应 过程并评估慢性HPA轴活动。在2，4个月和6个月的随访评估，访谈， 社交媒体数据，HPA轴活动和自我报告将被重新评估。总体目标是检查 生物过程与社交媒体暴露之间的关系，特别是关于 阐明自杀风险。首先，我们将测试社会神经网络改变是否会增加对 负面的社交媒体暴露。其次，我们将测试负面的社交媒体是否呈负面暴露 影响HPA轴活动。最后，我们将测试负面的社交媒体暴露，社交神经改变， HPA轴活动及其相互作用导致自杀事件的出现（即实际，中断或 流产的尝试；具有方法，意图或计划的主动自杀构想；急诊科或精神病学 STB的住院）。通过这种全面的方法，我们将解决一项关键的公共卫生计划 通过确定那些容易受到负面社交媒体暴露的人，并提供可行的标记 减少年轻人中不必要的生命损失。