The Environment-Gene Interface in Urologic Health and Disease

泌尿系统健康和疾病中的环境-基因界面

• 批准号: 9052367
• 负责人: Rosalyn M Adam
• 金额: $ 1万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-14 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9052367
• 关键词: Address; Affect; American; Americas; Area; Award; Basic Science; Biological Models; Bladder; Blinded; Cardiovascular Diseases; Clinical Research; Collaborations; Communities; Development; Diagnosis; Discipline; Disease; Dysplasia; Endocrine Disruptors; Ensure; Environment; Environmental Impact; Ethnic Origin; Functional disorder; Funding; Gender; Genes; Genitourinary system; Goals; Growth and Development function; Health; Health Care Costs; Healthcare; Human; Immune response; Immunity; Individual; Infection; Inflammation; Intervention; Investigation; Knowledge; Lead; Metabolic; Metabolic syndrome; Metabolism; Mission; Mutation; National Institute of Diabetes and Digestive and Kidney Diseases; Nutritional; Obesity; Oral; Organ; Pathogenesis; Pelvic Pain; Pelvis; Physicians; Physiology; Population; Prevention; Prevention strategy; Process; Prostate; Quality of life; Race; Request for Applications; Request for Proposals; Research; Research Personnel; Role; Scientist; Societies; Source; Therapeutic; Therapeutic Intervention; Training; Travel; Underrepresented Minority; United States; Urinary tract; Urogenital Diseases; Urologic Diseases; Urology; Work; abstracting; base; career; congenital anomaly; falls; frontier; graduate student; human disease; improved; innovation; lectures; meetings; member; minority trainee; novel strategies; outcome forecast; posters; public health relevance; sex; success; symposium; urologic

 DESCRIPTION (provided by applicant): This R13 proposal requests funds to support up to 30 travel awards of $500 each to the most promising trainee investigators (graduate students, postdoctoral trainees, residents and physician-scientist trainees) and to increase representation of underserved minorities of this status to attend and participate in the 2015 Fall Symposium of the Society for Basic Urologic Research (SBUR) to be held November 12th - 15th in Fort Lauderdale, FL. The SBUR is a society of basic and clinician-scientists specializing in research on normal growth and development, as well as pathological conditions of the genitourinary (GU) tract. Recent analyses conducted by the Urologic Diseases in America initiative indicates that conditions affecting the urinary tract represent a major healthcare burden in the US, with associated healthcare costs on the order of tens of billions of dollars annually. Given this burden, there is an urgent need to better understand the mechanisms underlying these diseases, develop strategies for prevention or intervention, and identify better treatments to improve quality of life for affected individuals The theme of the 2015 Fall Symposium is "The Environment-Gene Interface in Urologic Health and Disease". The specific aims of the Symposium are to: (i) Inspire young and established investigators to apply current knowledge in the field to advance the frontiers of basic and translational urologic research; (ii) Promote and advance the careers of new investigators in the field of urologic research; (iii) Provide a forum for networking, interaction, and establishing new collaborations between investigators focused in GU development and disease and those from other disciplines; (iv) Encourage creative thought on new approaches to study human GU development and disease that might lead to prevention or better therapeutics that reduce the health costs associated with these diseases and (v) Provide a forum for the dissemination of up-to-date scientific results pertaining to ongoing basic and clinical research on the common diseases of the human GU tract that are a source of extraordinary health costs in the United States and around the world. Research topics that will be covered during the Symposium include: 1) Nutritional aspects of urologic disease; 2) Metabolism, metabolic syndrome and the urinary tract; 3) Environmental disruptors and urologic disease; 4) Sex, race and ethnicity: impact on urologic disease; 5) Inflammation, infection and immunity in urology. Selection of travel awardees will proceed through a defined, rigorous process in which applicants are ranked by the Abstract Review Subcommittee based on the quality of submitted abstracts to identify the most promising trainees. The Executive Committee of the SBUR oversees selection of award recipients to ensure equitable representation of both genders and underserved minorities. If funded, this project will contribute to the educational objectives of the Symposium by promoting the participation of exceptional graduate students, postdoctoral trainees, residents and physician-scientist trainees, and enhance participation in urologic disease research by underrepresented minority trainees.

 描述（由申请人提供）： 该 R13 提案要求资金支持最多 30 个旅行奖励，每人 500 美元，奖励给最有前途的实习研究人员（研究生、博士后实习生、住院医师和医师科学家实习生），并增加这种状态下服务不足的少数群体的代表性，以参加和参与基础泌尿学研究学会 (SBUR) 2015 年秋季研讨会将于 11 月 12 日至 15 日在佛罗里达州劳德代尔堡举行。美国泌尿系统疾病倡议最近进行的分析表明，影响泌尿道的疾病是美国的主要医疗负担。每年相关的医疗费用约为数百亿美元，因此迫切需要更好地了解这些疾病的机制，制定预防或干预策略，并确定更好的治疗方法以提高生活质量。对于受影响的个人 2015 年秋季研讨会的主题是“泌尿系统健康和疾病中的环境与基因相互作用” 研讨会的具体目标是： (i) 激励年轻和成熟的研究人员应用该领域的最新知识来推进。基础和转化泌尿学研究的前沿； (ii) 促进和推进泌尿学研究领域新研究者的职业生涯； (iii) 提供交流、互动和建立新研究的论坛； 专注于 GU 发育和疾病的研究人员与其他学科的研究人员之间的合作；（iv）鼓励对研究人类 GU 发育和疾病的新方法进行创造性思考，这可能会导致预防或更好的治疗方法，从而降低与这些疾病相关的健康成本； v) 提供一个论坛，传播与人类泌尿道常见疾病正在进行的基础和临床研究相关的最新科学成果，这些疾病是美国和世界各地巨大健康成本的根源。将涵盖的主题研讨会期间包括： 1) 泌尿系统疾病的营养方面； 2) 代谢、代谢综合征和泌尿系统； 3) 环境干扰因素和泌尿系统疾病； 4) 性别、种族和民族：对泌尿系统疾病的影响；旅行获奖者的选择将通过一个明确的、严格的流程进行，摘要审查小组委员会根据提交的摘要的质量对申请人进行排名。 SBUR 执行委员会负责监督获奖者的选择，以确保性别和服务不足的少数群体的公平代表性。如果获得资助，该项目将通过促进优秀研究生的参与来促进研讨会的教育目标。 、博士后学员、住院医生和医师科学家学员，并加强代表性不足的少数族裔学员对泌尿系统疾病研究的参与。