Biobehavioral Processes Involved in Social Communication, Connectedness, and Adolescent Suicidal Thoughts and Behaviors

涉及社会沟通、联系和青少年自杀想法和行为的生物行为过程

• 批准号: 10686183
• 负责人: Kiera M James
• 金额: $ 6.95万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10686183
• 关键词: Adolescence; Adolescent; Affect; Affective; Area; Arousal; Attention; Attenuated; Behavior Disorders; Behavior assessment; Behavioral; Cause of Death; Child; Childhood; Clinical assessments; Conflict (Psychology); Cues; Data; Data Analyses; Development; Diagnostic; Diagnostic Factor; Dimensions; Disease; Distress; Early identification; Ecological momentary assessment; Empirical Research; Exhibits; Eye; Face; Feeling suicidal; Female Adolescents; Frequencies; Funding; Future; Goals; Grain; Grant; Incidence; Individual; Intervention; Laboratories; Link; Mood Disorders; Mydriasis; National Institute of Mental Health; Outcome; Parents; Participant; Physiological; Physiological Processes; Play; Prevention; Problem behavior; Process; Production; Psychopathology; RNA Interference; Reaction; Reporting; Research; Research Domain Criteria; Risk; Risk Behaviors; Role; Sample Size; Signal Transduction; Silk; Social Interaction; Social Processes; Stress; Suicide; Suicide attempt; Temperament; Testing; Theoretical model; Training; Transcend; United States; Youth; aged; biobehavior; boys; bullying; cost effective; follow up assessment; follow-up; gaze; girls; member; multimodality; novel; peer; prospective; reducing suicide; response; social; social communication; social factors; social inclusion; suicidal adolescent; suicidal behavior; suicidal risk; suicide model; suicide rate; theories; therapeutic target; visual tracking

PROJECT SUMMARY. In the United States, suicide is the second leading cause of death with approximately 7,000 suicides occurring annually among those aged 10-24. Critically, these numbers are rising among youth, and rates of serious suicidal thoughts and behaviors (STBs) are staggering, particularly among adolescent girls. Both theory and empirical research suggest that social factors play a putative role in risk for suicide among youth. Moreover, prior research implicates social communication – facial and non-facial cues exchanged during social interaction – in these social factors (e.g., connectedness). Yet, research examining fine-grained biobehavioral processes involved in social communication during interaction is extremely limited. The goal of this proposal, therefore, is to take a multiple-units-of-analysis approach to examine adolescent girls' social communication production and reception during actual social interactions, and determine whether alterations in biobehavioral processes involved in social communication directly and independently contribute to girls' subsequent (i) day- to-day social connectedness and (ii) STBs. An additional, exploratory aim will be to examine whether these biobehavioral processes indirectly impact girls' STBs through their effects on day-to-day social connectedness. Biobehavioral processes will include specific behavioral (i.e., eye-gaze and facial affect) and physiological (i.e., electrodermal activity [EDA] and pupil dilation) processes. Thus, this proposal will examine whether girls who demonstrate disrupted social communication (i.e., reduced eye-gaze, positive facial affect, and EDA reciprocity; attenuated gaze-contingent positive facial affect and EDA responses) will be less likely to exhibit future day-to- day social connectedness with parents and peers (Hypothesis 1). Next, this proposal will examine whether girls who demonstrate disruptions in the same biobehavioral processes involved in social communication will be more likely to report future STB onset (Hypothesis 2). Finally, exploratory analyses will examine day-to-day social disconnectedness as a potential mechanism through which deficits in social communication increase girls' STB risk. Participants for the proposed study will be adolescent girls drawn from an R01 grant, involving multimodal assessment during a laboratory-based parent-adolescent interaction task with girls (aged 11-13), follow-up ecological momentary assessment of day-to-day social connectedness two years later (aged 13-15), and STB assessments two (aged 13-15) and three years (aged 14-16) after the initial assessment. The sample size at baseline comprised 129 dyads, and 119 dyads were retained at the two-year follow up. Three-year follow-up assessments are ongoing. Under the guidance of leading experts in the field, training areas to facilitate future investigative independence include: ecological momentary assessment, mobile eye-tracking, longitudinal data analysis, and professional development. This type of nuanced, integrative research is essential to the identification of mechanisms of risk that can be therapeutically targeted to reduce STB risk during key windows of risk.

项目摘要。在美国，自杀是死亡的第二大原因 10-24岁的人每年发生7,000起自杀。至关重要的是，这些数字在年轻人中有所增加， 严重的自杀思想和行为（STB）的速度令人震惊，尤其是在青春期中。 理论和实证研究都表明，社会因素在年轻人自杀的风险中起着推定的作用。 此外，先前的研究含义社会交流 - 社会期间交换的面部和非种族提示 互动 - 在这些社会因素（例如，连接性）中。但是，研究了研究细粒生物行为的研究 互动期间社交交流所涉及的过程极为有限。该提议的目标， 因此，要采用多重分析方法来检查青春期女孩的社会交流 实际社交互动期间的生产和接收，并确定生物行为的改变是否 与社会交流有关的过程直接，独立地为女孩的随后（i）日做出了贡献 - 今天的社会联系和（ii）STB。另一个探索性的目的是检查这些是否是否 生物行为过程通过对日常社会联系的影响间接影响女孩的STB。 生物行为过程将包括特定的行为（即眼睛注视和面部影响）和生理学（即， 电性活动[EDA]和学生词典）过程。那，该提议将检查是否 表现出破坏的社会交流（即减少眼睛的视线，积极的面部影响和EDA互惠； 衰减的注视症状正面影响和EDA反应不太可能表现出未来的日常生活 与父母和同龄人的日间社会联系（假设1）。接下来，该提议将检查女孩是否 在社交交流所涉及的同一生物行为过程中表现出中断的人将更多 可能报告未来的STB发作（假设2）。最后，探索性分析将检查日常的社交 断开连接是一种潜在的机制，在社会交流中定义了女孩的STB 风险。拟议研究的参与者将是从R01赠款中吸引的青春期女孩，涉及多模式 在基于实验室的父母与女孩与女孩的互动任务（11-13岁）期间的评估，随访 两年后（13-15岁）和STB对日常社会联系的生态瞬时评估 初步评估后评估2（13-15岁）和三岁（14-16岁）。样本量 在为期两年的随访中，基线完成了129个二元组，并保留了119个二元组。三年随访 评估正在进行中。在该领域的领先专家的指导下，培训领域以促进未来 调查独立性包括：生态瞬时评估，移动眼球跟踪，纵向数据 分析和专业发展。这种细微的综合研究对于 识别可以在关键窗口中降低STB风险的风险机制的识别 风险。

项目成果

Self- and co-regulation of physiological activity during mother-daughter interactions: The role of adolescent non-suicidal self-injury.

母女互动期间生理活动的自我调节和共同调节：青少年非自杀性自残的作用。

• DOI: 10.1111/jcpp.13859
• 发表时间: 2024
• 期刊: Journal of child psychology and psychiatry, and allied disciplines
• 作者: James,KieraM;Balderrama-Durbin,Christina;Israel,Elana;Feurer,Cope;Gibb,BrandonE
• 通讯作者: Gibb,BrandonE

Attentional capture by angry faces in girls who self-injure: Evidence from steady state visual evoked potentials.

• DOI: 10.1111/sltb.12909
• 发表时间: 2022-12
• 期刊: SUICIDE AND LIFE-THREATENING BEHAVIOR
• 影响因子: 3.2
• 作者: James, Kiera M.;Miskovic, Vladimir;Woody, Mary L.;Owens, Max;Connolly, Evan;Gibb, Brandon E.
• 通讯作者: Gibb, Brandon E.

Peer Connectedness and Social Technology Use During COVID-19 Lockdown.

• DOI: 10.1007/s10802-023-01040-5
• 发表时间: 2023-07
• 期刊: RESEARCH ON CHILD AND ADOLESCENT PSYCHOPATHOLOGY
• 影响因子: 2.5
• 作者: James, Kiera M.;Silk, Jennifer S.;Scott, Lori N.;Hutchinson, Emily A.;Wang, Sarah;Sequeira, Stefanie L.;Lu, Celine;Oppenheimer, Caroline;Ladouceur, Cecile D.
• 通讯作者: Ladouceur, Cecile D.

Dynamics of Affective Reactivity during Mother-Daughter Interactions: The Impact of Adolescent Non-Suicidal Self-Injury.

• DOI: 10.1007/s10802-022-01011-2
• 发表时间: 2023-05
• 期刊: RESEARCH ON CHILD AND ADOLESCENT PSYCHOPATHOLOGY
• 影响因子: 2.5
• 作者: James, Kiera M. M.;Balderrama-Durbin, Christina;Kobezak, Holly M. M.;Recchia, Nicolette;Foster, Claire E. E.;Gibb, Brandon E. E.
• 通讯作者: Gibb, Brandon E. E.

Adolescents' neural reactivity to parental criticism is associated with diminished happiness during daily interpersonal situations.

• DOI: 10.1093/scan/nsad020
• 发表时间: 2023-04-13
• 期刊: SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
• 影响因子: 4.2
• 作者: James, Kiera M.;Sequeira, Stefanie L.;Dahl, Ronald E.;Forbes, Erika E.;Ryan, Neal D.;Hooley, Jill;Ladouceur, Cecile D.;Silk, Jennifer S.
• 通讯作者: Silk, Jennifer S.