Building Community and Research Engagement among Sexual and Gender Minority Older Adults at Risk for Alzheimer’s Disease and Related Dementias

在有阿尔茨海默病和相关痴呆症风险的性少数群体老年人中建立社区和研究参与

• 批准号: 10685369
• 负责人: Joel G. Anderson
• 金额: $ 72.73万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10685369
• 关键词: Address; Adult; Affect; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Alzheimer' s disease risk; Cardiovascular Diseases; Caregivers; Caring; Clinic; Clinical; Clinical Research; Clinical Trials; Communities; Community Networks; Community Participation; Data; Data Collection; Dementia caregivers; Development; Diabetes Mellitus; Distress; Documentation; Economics; Elderly; Enrollment; Evaluation; Event; Focus Groups; Funding; Future; Goals; Health; Health education; Heterosexuals; High Prevalence; Hypertension; Impaired cognition; Institution; Intervention Studies; Lesbian Gay Bisexual Transgender; Mental Depression; Modeling; National Institute on Aging; Needs Assessment; Nursing Staff; Output; Parents; Participant; Personal Satisfaction; Persons; Population Heterogeneity; Provider; Psyche structure; Registries; Research; Research Activity; Research Methodology; Research Personnel; Research Project Grants; Resources; Sampling; Services; Sexual and Gender Minorities; Site; Strategic Planning; Surveys; United States National Institutes of Health; aged; cisgender; cohort; community based participatory research; community based service; community building; community organizations; dementia risk; ethnic diversity; experience; gender minority community; gender minority group; health data; health disparity; improved; informal caregiving; interest; member; minority engagement; minority healthcare; minority patient; online registry; outreach program; pilot test; programs; queer; racial diversity; recruit; research and development; research study; retention rate; satisfaction; service providers; sociodemographics; socioeconomics; virtual

Abstract By 2030, there will be nearly six million sexual and gender minority (SGM) older adults aged 50 and older in the U.S. who identify as lesbian, gay, bisexual, transgender, and/or queer. This number will more than double by 2050. Approximately 350,000 SGM older adults in the U.S. currently are living with Alzheimer's disease and related dementias (ADRD), with projections nearing one million by 2030. SGM older adults experience greater health disparities than their heterosexual counterparts. Several recent studies have shown a higher prevalence of risk factors for ADRD, including higher rates of cardiovascular disease, hypertension, diabetes, depression or frequent mental distress, and subjective cognitive decline. In addition, SGM older adults are less likely to have informal caregiving support and for those with caregivers, their caregivers often lack access to inclusive services and resources. Research participation from SGM older adults is extremely limited and the sparse research suggests that SGM older adults are interested in being engaged in research, but concerns regarding the lack of inclusive services and mistrust need to be addressed to improve participation in ADRD research, including clinical trials and intervention research studies. To overcome these barriers to participation in ADRD- related research, this study will implement culturally appropriate and inclusive recruitment strategies aimed at engaging, recruiting, and retaining SGM older adults with ADRD and SGM caregivers in research. This will be accomplished through (1) the development of a national network of existing SGM organizations, programs, and academic institutions to engage SGM people with ADRD and SGM ADRD caregivers in clinical research; 2) establishing a sustainable research registry of SGM people with ADRD and SGM caregivers by developing, implementing, and evaluating tailored recruitment and engagement programs, for use by ADRDc and clinical research institutions; and 3) the development of a replicable model for recruitment and retention of SGM people with ADRD and SGM caregivers in ADRD and aging-related research. Our collaborative team will address the National Institute of Aging's Strategic Directions for Research on Aging “F-3: Develop and implement strategies to increase inclusion of diverse populations in research.”

抽象的 到 2030 年，50 岁及以上的性少数群体 (SGM) 老年人将接近 600 万 在美国，女同性恋、男同性恋、双性恋、跨性别者和/或酷儿的人数将增加一倍以上。 到 2050 年。目前美国约有 350,000 名 SGM 老年人患有阿尔茨海默病和 相关痴呆症（ADRD），预计到 2030 年将接近 100 万。SGM 老年人经历的 最近的几项研究表明，健康差异高于异性恋。 ADRD 的危险因素，包括心血管疾病、高血压、糖尿病、抑郁症的发病率较高 或经常精神困扰，以及主观认知能力下降。此外，SGM老年人出现这种情况的可能性较小。 拥有非正式的护理支持，对于那些有护理人员的人来说，他们的护理人员往往无法获得包容性的服务 SGM 老年人参与的研究极其有限且稀少。 研究表明，SGM 老年人有兴趣从事研究，但担心 需要解决缺乏包容性服务和不信任的问题，以提高 ADRD 研究的参与度， 包括临床试验和干预研究，以克服参与 ADRD 的这些障碍。 相关研究，本研究将实施文化上适当和包容性的招聘战略，旨在 吸引、招募和保留患有 ADRD 的 SGM 老年人和 SGM 护理人员参与研究。 通过 (1) 发展现有 SGM 组织、计划和项目的全国网络 学术机构让患有 ADRD 的 SGM 人员和 SGM ADRD 护理人员参与临床研究 2) 通过开发、 实施和评估量身定制的招募和参与计划，供 ADRDc 和临床使用 研究机构；以及 3) 开发可复制的 SGM 招募和保留模型 ADRD 患者和 SGM 护理人员从事 ADRD 和衰老相关研究。 阐述国家老龄化研究所的老龄化研究战略方向“F-3：开发和 实施战略以增加不同人群参与研究的程度。”

项目成果

Advancing Gerontological Health Research With Sexual and Gender Minorities Across the Globe.

• DOI: 10.3928/00989134-20220304-03
• 发表时间: 2022-04
• 期刊: Journal of gerontological nursing
• 影响因子: 1.3
• 作者: Flatt JD;Cicero EC;Kittle KR;Brennan-Ing M;Anderson JG;Wharton W;Hughes TL
• 通讯作者: Hughes TL

Inclusive Care Practices and Policies Among Sexual and Gender Minority Older Adults.

性和性别少数老年人的包容性护理实践和政策。

• DOI: 10.3928/00989134-20221107-03
• 发表时间: 2022
• 期刊: Journal of gerontological nursing
• 影响因子: 1.3
• 作者: Anderson,JoelG;Flatt,JasonD;Cicero,EthanC;Kittle,Krystal;Myers,CaroleR;Rose,KarenM;Wharton,Whitney
• 通讯作者: Wharton,Whitney

Transgender Adults From Minoritized Ethnoracial Groups in the U.S. Report Greater Subjective Cognitive Decline.

美国少数族裔群体的跨性别成年人主观认知能力下降幅度更大。

• DOI: 10.1093/geronb/gbad012
• 发表时间: 2023
• 期刊: The journals of gerontology. Series B, Psychological sciences and social sciences
• 作者: Cicero,EthanC;Lett,Elle;Flatt,JasonD;Benson,GPerusi;Epps,Fayron
• 通讯作者: Epps,Fayron