Developmental Research Program

发展研究计划

• 批准号: 10683763
• 负责人: Walter J. Storkus
• 金额: $ 9.06万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10683763
• 关键词: Advocate; Applications Grants; Area; Award; Basic Science; Biological Response Modifier Therapy; Cancer Center; Clinic; Clinical; Clinical Research; Collaborations; Communities; Comprehensive Cancer Center; Data; Development; Eligibility Determination; Extramural Activities; Feedback; Funding; Future; Goals; Grant; Immunotherapy; Institution; International; Mentors; Ohio; Patients; Peer Review; Pilot Projects; Preparation; Process; Program Research Project Grants; Publications; Research; Research Personnel; Research Support; Resources; Roswell Park Cancer Institute; Services; Skin Cancer; Source; System; Time; Translational Research; Translations; United States National Institutes of Health; Universities; broadening participation research; cancer therapy; high reward; high risk; innovation; meetings; melanoma; member; novel; programs; recruit; symposium; working group

ABSTRACT: Developmental Research Program (DRP) The MSCP SPORE Developmental Research Program (DRP) provides seed funding to explore promising novel research in melanoma and other skin cancers, particularly by investigators not currently engaged in research in this area. The DRP will solicit proposals 1-2 times per year and applies a peer-reviewed scoring system to prioritize the funding of 2-3 proposals per year at up to $75K/proposal/year. The DRP and SPORE Co-Directors, Regional Melanoma Consortium (RMC) representatives, and members of our SPORE Internal Advisory Board (IAB) and External Advisory Board (EAB) participate in the review process, together with Patient Advocates and any additional experts necessary to judge project feasibility, translational significance and likely overall impact. During the most recent period of funding, the MSCP SPORE supported 9 DRP projects in basic, translational, and clinical research. The DRP Co-Directors track the progress of the successful applications and assign mentors to funded investigators to ensure that they obtain any needed services from the MSCP SPORE Cores, and that they are effectively integrated into the SPORE program. Awardees present their research results to the MSCP SPORE membership after one year of funding to become eligible for a second year of support. Progress toward translation as well as impact and innovation will determine whether DRP projects are found to merit promotion to full SPORE projects at the time of formulating a renewal bid. Awardees are also advised as appropriate in the preparation of grant applications for funding outside the SPORE mechanism and given access to all SPORE Core resources to aid in this endeavor. DRP- supported research over the most recent period of support resulted in funded NIH R01, R21 and P01 grants, numerous publications and presentations at local, national and international meetings/symposia that serve to enhance MSC SPORE visibility on a global level.

摘要：发展研究计划（DRP） MSCP孢子发育研究计划（DRP）提供了种子资金来探索有希望的 黑色素瘤和其他皮肤癌的新研究，特别是目前尚未参与的研究人员 该领域的研究。 DRP每年将征集提案1-2次，并采用同行评审的评分 系统以每年2-3个建议的资金为优先级，最高为75K/提案/年。 DRP和孢子 联合导演，区域黑色素瘤联盟（RMC）代表和我们的孢子内部成员 顾问委员会（IAB）和外部顾问委员会（EAB）参与了审核过程 患者拥护者和任何其他判断项目可行性所需的其他专家，翻译意义 并可能的整体影响。在最近的资金期间，MSCP孢子支持9 DRP 基础，转化和临床研究项目。 DRP联合导演跟踪 成功的申请并将导师分配给资助的调查人员，以确保他们获得任何所需的 MSCP孢子核心的服务，并有效地集成到孢子计划中。 一年后，获奖者向MSCP Spore会员资格介绍了他们的研究结果 有资格获得第二年的支持。朝着翻译以及影响和创新的进展将 确定是否发现DRP项目值得在制定时晋升为全孢子项目 更新出价。还建议获奖者在准备资金授予申请时适当 在孢子机制之外，并获得了所有孢子核心资源的访问，以帮助这项工作。 drp- 在最近的支持期间的支持研究导致了资助的NIH R01，R21和P01赠款， 在本地，国家和国际会议/研讨会上进行的众多出版物和演讲 在全球范围内增强MSC孢子的可见性。