Developmental Research Program

发展研究计划

• 批准号: 10469638
• 负责人: Walter J. Storkus
• 金额: $ 7.8万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10469638
• 关键词: Advocate; Applications Grants; Area; Award; Basic Science; Biological Response Modifier Therapy; Cancer Center; Clinic; Clinical Research; Collaborations; Communities; Comprehensive Cancer Center; Cutaneous Melanoma; Data; Development; Ensure; Extramural Activities; Feedback; Funding; Future; Goals; Grant; Immunotherapy; Institutes; Institution; International; Malignant Neoplasms; Mentors; Ohio; Patients; Peer Review; Pilot Projects; Preparation; Process; Program Research Project Grants; Publications; Research; Research Personnel; Research Support; Resources; Seeds; Services; Skin Cancer; Source; System; Time; Translational Research; Translations; United States National Institutes of Health; Universities; base; cancer therapy; high reward; high risk; innovation; meetings; melanoma; member; novel; programs; recruit; symposium; working group

ABSTRACT: Developmental Research Program (DRP) The MSCP SPORE Developmental Research Program (DRP) provides seed funding to explore promising novel research in melanoma and other skin cancers, particularly by investigators not currently engaged in research in this area. The DRP will solicit proposals 1-2 times per year and applies a peer-reviewed scoring system to prioritize the funding of 2-3 proposals per year at up to $75K/proposal/year. The DRP and SPORE Co-Directors, Regional Melanoma Consortium (RMC) representatives, and members of our SPORE Internal Advisory Board (IAB) and External Advisory Board (EAB) participate in the review process, together with Patient Advocates and any additional experts necessary to judge project feasibility, translational significance and likely overall impact. During the most recent period of funding, the MSCP SPORE supported 9 DRP projects in basic, translational, and clinical research. The DRP Co-Directors track the progress of the successful applications and assign mentors to funded investigators to ensure that they obtain any needed services from the MSCP SPORE Cores, and that they are effectively integrated into the SPORE program. Awardees present their research results to the MSCP SPORE membership after one year of funding to become eligible for a second year of support. Progress toward translation as well as impact and innovation will determine whether DRP projects are found to merit promotion to full SPORE projects at the time of formulating a renewal bid. Awardees are also advised as appropriate in the preparation of grant applications for funding outside the SPORE mechanism and given access to all SPORE Core resources to aid in this endeavor. DRP- supported research over the most recent period of support resulted in funded NIH R01, R21 and P01 grants, numerous publications and presentations at local, national and international meetings/symposia that serve to enhance MSC SPORE visibility on a global level.

摘要：发展研究计划（DRP） MSCP SPORE 发展研究计划 (DRP) 提供种子资金来探索有前途的研究 关于黑色素瘤和其他皮肤癌的新研究，特别是由目前尚未从事的研究人员进行的研究 该领域的研究。 DRP 每年将征集 1-2 次提案并采用同行评审评分 系统每年优先为 2-3 个提案提供资助，每个提案每年最高可达 75,000 美元。 DRP 和 SPORE 联合董事、区域黑色素瘤联盟 (RMC) 代表以及 SPORE 内部成员 顾问委员会 (IAB) 和外部顾问委员会 (EAB) 参与审核过程， 患者权益倡导者和判断项目可行性、转化意义所需的任何其他专家 以及可能的总体影响。在最近的资助期间，MSCP SPORE 支持了 9 个 DRP 基础、转化和临床研究项目。 DRP 联合董事跟踪项目的进展情况 成功申请并向受资助的研究人员指派导师，以确保他们获得所需的任何信息 来自 MSCP SPORE 核心的服务，并且它们有效地集成到 SPORE 程序中。 经过一年的资助后，获奖者向 MSCP SPORE 会员展示他们的研究成果 有资格获得第二年的支持。翻译以及影响力和创新方面的进展将 在制定时确定 DRP 项目是否值得升级为完整的 SPORE 项目 续订出价。还酌情建议获奖者准备资助申请 在 SPORE 机制之外，并有权访问所有 SPORE 核心资源以帮助实现这一目标。 DRP- 最近一段时间的支持研究获得了 NIH R01、R21 和 P01 拨款， 在地方、国家和国际会议/研讨会上发表了大量出版物和演讲，有助于 提高 MSC SPORE 在全球的知名度。