A Text-Based Scheduled Reduction Intervention for Smokeless Tobacco Cessation

基于文本的无烟烟草戒烟计划减少干预措施

• 批准号: 10703375
• 负责人: Devon Noonan
• 金额: $ 36.09万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10703375
• 关键词: Address; Algorithms; American; Behavior; Cellular Phone; Chronic Disease; Control Groups; Counseling; Cues; Disparity; Foundations; Funding; Goals; Individual; Informal Social Control; Intervention; Investigation; Learning; Malignant Neoplasms; Mastication; Measures; Mediating; Medically Underserved Area; Methods; Morbidity - disease rate; Participant; Patient Self-Report; Pattern; Population; Randomized, Controlled Trials; Reporting; Research; Risk; Schedule; Smokeless; Smokeless Tobacco; Smoking Cessation Intervention; Testing; Text; Text Messaging; Tobacco; Tobacco use; Tobacco-Related Carcinoma; Underserved Population; Withdrawal; Withdrawal Symptom; Work; acceptability and feasibility; cancer health disparity; cigarette smoking; common symptom; comparison intervention; craving; effective intervention; efficacy evaluation; efficacy testing; experience; feasibility testing; follow-up; health disparity; high risk; innovation; intervention effect; male; malignant mouth neoplasm; medically underserved; medically underserved population; mortality; post intervention; primary outcome; programs; randomized, clinical trials; recruit; response; restraint; rural Americans; rural underserved; secondary outcome; smokeless tobacco cessation; smokeless tobacco use; smokeless tobacco user; smoking cessation; text messaging intervention; texting support; tobacco abstinence; tobacco cessation intervention; tobacco user; trial design

Project Summary Smokeless tobacco (chew or dip) use remains prevalent in rural and medically underserved populations, leading to increased rates of tobacco-related cancers and chronic disease. Yet, underserved tobacco users who want to quit have access to few innovative interventions. This is a significant missed opportunity to address health disparities in this group. Scheduled Gradual Reduction (SGR) may be an effective intervention to help smokeless tobacco users quit. SGR addresses common cessation challenges faced by smokeless tobacco users including the strong cue-based component of use and strong withdrawal symptoms. The SGR method been minimally studied in this population of tobacco users and represents an innovative new direction in the field. SGR involves gradually tapering smokeless tobacco use through lengthening use intervals based on an individually tailored schedule. SGR helps smokeless tobacco users learn to refrain from chew/dips that are in environmental cues by following the schedule and gradually reducing their use. Delivering SGR interventions via text messaging is an innovative way to increase the reach of this cessation intervention in underserved populations. Therefore, we propose a randomized clinical trial to evaluate the efficacy of a SGR Intervention (SGR intervention plus text-based support messages) vs. control intervention (text-based support messages) in decreasing smokeless tobacco use. The SGR group (N=250) will receive a six-week SGR program and text-based support messages. The control group (N=250) will receive text-based support messages. The primary outcome will be self-report smokeless tobacco cessation at 6 months. We will also test the efficacy of the text-based SGR intervention compared to support messages only on changes in withdrawal, craving, self-regulation and restraint across the 6-month period and explore whether changes in withdrawal, craving, self-regulation and restraint mediate intervention effects on self- reported cessation at 6 months post-intervention. Results of this study can be disseminated broadly to help smokeless tobacco users quit with the ultimate goal of increasing access to efficacious cessation interventions and eliminating cancer health disparities.

项目摘要 无烟烟草（咀嚼或蘸酱）在农村和医学欠缺的人群中仍然普遍存在 导致与烟草相关的癌症和慢性病的发生率增加。但是，服务不足的烟草用户 想要退出的人可以访问一些创新的干预措施。这是一个重要的错过的机会 解决该组的健康差异。预定的逐渐减少（SGR）可能是有效的 干预以帮助无烟烟草用户退出。 SGR解决了面临的常见戒烟挑战 无烟烟草使用者，包括强大的使用组件和强大的戒断 症状。 SGR方法在该烟草用户中最少研究，并代表 创新的新方向。 SGR涉及逐渐逐渐变细的无烟烟草。 基于单独量身定制的时间表的延长使用时间间隔。 SGR帮助无烟烟草用户 通过遵循时间表并逐渐减少 他们的使用。通过文本消息传递SGR干预措施是一种创新的方法来提高其影响力 停止干预服务不足的人群。因此，我们提出了一项随机临床试验 评估SGR干预措施（SGR干预加上基于文本的支持消息）与控制的功效 干预（基于文本的支持消息）减少无烟烟草的使用。 SGR组（n = 250） 将收到一个为期六周的SGR计划和基于文本的支持消息。对照组（n = 250）将 接收基于文本的支持消息。主要结果将是自我报告无烟烟草戒烟 6个月。与支持消息相比，我们还将测试基于文本的SGR干预的功效 仅在整个6个月的戒断，渴望，自我调节和克制的变化并进行探索 戒断，渴望，自我调节和约束的变化是否介导了干预对自我的影响 报告在干预后6个月停止。这项研究的结果可以广泛传播以帮助 无烟烟草用户辞职的最终目标是增加获得有效戒烟干预措施 并消除癌症健康差异。