LOTUS: An mHealth Intervention to Improve HIV Prevention Service Engagement and Intersectional Stigma among Racially Diverse Women Who Use Drugs

LOTUS：一项移动医疗干预措施，旨在提高艾滋病毒预防服务的参与度，并消除吸毒的不同种族女性之间的交叉耻辱

• 批准号: 10678886
• 负责人: Stephanie Alice Meyers-Pantele
• 金额: $ 18.02万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10678886
• 关键词: AIDS prevention; Address; Adherence; Adopted; Adoption; Affect; African American; Awareness; Behavior Therapy; Biological; Black race; California; Characteristics; Clinic; Communicable Diseases; Communities; Consolidated Framework for Implementation Research; Coping Skills; County; Data; Development; Discrimination; Drug usage; Drug user; Educational workshop; Eligibility Determination; Employee; Environment; Epidemic; Feedback; Fostering; Future; Gender; Goals; HIV; HIV Infections; HIV Seronegativity; HIV disparities; HIV/STD; Health; Health behavior; Hybrids; Incidence; Individual; Instruction; Intervention; Interview; Knowledge; Latina; Link; Measures; Medical; Mentored Research Scientist Development Award; Mentors; Methods; Morality; Participant; Patient Self-Report; Population; Positioning Attribute; Prevention Research; Procedures; Process; Productivity; Provider; Public Health; Qualitative Methods; Race; Randomized; Randomized, Controlled Trials; Research; Risk; Scientist; Services; Social support; Stimulant; Suggestion; Testing; Training; United States Dept. of Health and Human Services; Universities; Violence; Woman; base; career; cis-female; community organizations; design; ethnic diversity; experience; hands on research; health care availability; health care service; health equity; implementation science; improved; informant; intersectionality; mHealth; member; men; motherhood; novel; opioid use; pre-exposure prophylaxis; prevention service; racial diversity; secondary analysis; service engagement; skill acquisition; skills; social norm; social stigma; substance use; theories; therapy design; therapy development; transmission process; uptake; usability; user centered design

PROJECT SUMMARY/ABSTRACT Candidate. Dr. Meyers-Pantele applies for this K01 mentored training award with the independent career goal of attaining a productive and independent research career as a health behavior interventionist focused on reducing HIV disparities among women who use drugs (WWUD). Her current training, however, does not extend beyond the secondary analysis of stigma, and substance use data, and is insufficient for in-depth instruction on the theoretical and practical methods required for the development and implementation of health behavior interventions for racially and ethnically diverse WWUD. Specifically, the K01 training will support her transition to an independent career scientist by: (1) developing proficiency in intersectionality theory to inform an intervention targeting HIV prevention service engagement and intersectional stigma for racially diverse WWUD, (2) gaining expertise in mHealth intervention design and development to create the proposed mHealth intervention, (3) building proficiency in the implementation of randomized controlled trials to pilot the developed intervention, (4) strengthening her skill base in implementation science to design an intervention that has the potential for adoption and implementation, and (5) fostering the personal development skills necessary for a successful academic career. These training aims will be accomplished through didactic courses, training workshops, participation in professional research networks, hands-on research, and mentored training. Research and Environment. WWUD are at increased risk for HIV and have low levels of pre-exposure prophylaxis knowledge and acceptance. Additionally, racially and ethnically diverse WWUD experience intersectional stigma due to gendered and racialized social norms surrounding womanhood, motherhood, morality, substance use, and criminality, all of which have important implications for women’s engagement with HIV prevention services. Mobile health (mHealth) interventions and interventions that target intersectional stigma have the potential to increase HIV prevention service engagement, but there is a dearth of interventions tailored toward racially diverse WWUD. The proposed research will provide Dr. Meyers-Pantele with the training to address this critical gap in HIV prevention research. She will employ qualitative methods to identify key experiences with HIV prevention services and intersectional stigma, and potential barriers and facilitators to intervention adoption and implementation, to inform the development of potential theory-driven mHealth intervention components. This information will be used to develop and test the usability of the mheaLth interventiOn To redUce Stigma (LOTUS) intervention to improve HIV prevention service engagement and intersectional stigma for racially and ethnically diverse WWUD. Lastly, she will conduct a pilot RCT to assess the feasibility, acceptability, and preliminary impact of the LOTUS intervention. This training will uniquely position her as one of few mHealth interventionists specializing in intersectional stigma for WWUD at UCSD.

项目摘要/摘要 候选人。 Meyers-Pantele博士申请该K01称为培训奖，并具有独立职业目标 作为健康行为干预主义者的富有成效和独立的研究职业，专注于 减少使用药物（WWUD）女性的艾滋病毒差异。但是，她目前的培训不是 延伸超出了污名和物质使用数据的次要分析，不足以深入 关于健康发展和实施所需的理论和实用方法的指导 大致和种族多样的wwud的行为干预措施。具体来说，K01培训将支持她 通过以下方式过渡到独立职业科学家 针对艾滋病毒预防服务参与的干预措施和种族潜水员的交叉污名 WWUD，（2）获得MHealth干预设计和开发方面的专业知识，以创建拟议的MHealth 干预，（3）实施随机对照试验的建筑水平以试行开发的 干预，（4）加强她在实施科学领域的技能基础，以设计具有 采用和实施的潜力，以及（5）培养一个人的个人发展技能 成功的学术生涯。这些培训目标将通过教学课程，培训来实现 讲习班，参与专业研究网络，动手研究和指导培训。 研究与环境。 WWUD的艾滋病毒风险增加，暴露前的水平较低 预防知识和接受。此外，种族和种族多样化的WWUD经验 由于性别和种族化的社会规范，围绕女性，母性， 道德，毒品使用和犯罪性，所有这些都对妇女的参与都有重要影响 艾滋病毒预防服务。移动健康（MHealth）的干预措施和干预措施针对代祷 污名有可能增加艾滋病毒预防服务的参与，但干预死亡 针对大致潜水员量身定制。拟议的研究将为Meyers-Pantele博士提供 培训以解决艾滋病毒预防研究中的这一关键差距。她将采用定性方法来识别 艾滋病毒预防服务和交叉污名以及潜在的障碍和促进者的关键经验 采用和实施干预，以告知潜在理论驱动的MHealth的发展 干预组件。此信息将用于开发和测试MHealth的可用性 干预以减少污名（Lotus）干预以改善艾滋病毒预防服务的参与和 大致和种族多样的WWUD的横断面污名。最后，她将进行一名飞行员RCT来评估 莲花干预的可行性，可接受性和初步影响。该培训将独特 将她定位为在UCSD上专门从事WWUD交叉污名的少数MHealth干预主义者之一。