LOTUS: An mHealth Intervention to Improve HIV Prevention Service Engagement and Intersectional Stigma among Racially Diverse Women Who Use Drugs

LOTUS：一项移动医疗干预措施，旨在提高艾滋病毒预防服务的参与度，并消除吸毒的不同种族女性之间的交叉耻辱

• 批准号: 10548662
• 负责人: Stephanie Alice Meyers-Pantele
• 金额: $ 18.02万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10548662
• 关键词: AIDS prevention; Address; Adherence; Adopted; Adoption; Affect; African American; Awareness; Behavior Therapy; Biological; Black race; California; Centers for Disease Control and Prevention (U.S.); Characteristics; Clinic; Communicable Diseases; Communities; Consolidated Framework for Implementation Research; Coping Skills; County; Data; Development; Discrimination; Drug usage; Drug user; Educational workshop; Eligibility Determination; Employee; Environment; Epidemic; Feedback; Fostering; Future; Gender; Goals; HIV; HIV Infections; HIV Seronegativity; HIV/STD; Health; Health behavior; Hybrids; Incidence; Individual; Instruction; Intervention; Interview; Knowledge; Latina; Link; Measures; Medical; Mentored Research Scientist Development Award; Mentors; Methods; Morality; Participant; Patient Self-Report; Population; Positioning Attribute; Prevention Research; Procedures; Process; Provider; Public Health; Qualitative Methods; Randomized; Randomized Controlled Trials; Research; Research Training; Risk; Scientist; Services; Social support; Stimulant; Suggestion; Testing; Training; Triad Acrylic Resin; United States Dept. of Health and Human Services; Universities; Violence; Woman; base; career; cis-female; community clinic; design; ethnic diversity; experience; hands on research; health care availability; health care service; health equity; implementation science; improved; informant; intersectionality; mHealth; member; men; motherhood; novel; opioid use; pre-exposure prophylaxis; prevention service; racial diversity; secondary analysis; service engagement; skill acquisition; skills; social norm; social stigma; substance use; theories; therapy design; therapy development; transmission process; uptake; usability; user centered design

PROJECT SUMMARY/ABSTRACT Candidate. Dr. Meyers-Pantele applies for this K01 mentored training award with the independent career goal of attaining a productive and independent research career as a health behavior interventionist focused on reducing HIV disparities among women who use drugs (WWUD). Her current training, however, does not extend beyond the secondary analysis of stigma, and substance use data, and is insufficient for in-depth instruction on the theoretical and practical methods required for the development and implementation of health behavior interventions for racially and ethnically diverse WWUD. Specifically, the K01 training will support her transition to an independent career scientist by: (1) developing proficiency in intersectionality theory to inform an intervention targeting HIV prevention service engagement and intersectional stigma for racially diverse WWUD, (2) gaining expertise in mHealth intervention design and development to create the proposed mHealth intervention, (3) building proficiency in the implementation of randomized controlled trials to pilot the developed intervention, (4) strengthening her skill base in implementation science to design an intervention that has the potential for adoption and implementation, and (5) fostering the personal development skills necessary for a successful academic career. These training aims will be accomplished through didactic courses, training workshops, participation in professional research networks, hands-on research, and mentored training. Research and Environment. WWUD are at increased risk for HIV and have low levels of pre-exposure prophylaxis knowledge and acceptance. Additionally, racially and ethnically diverse WWUD experience intersectional stigma due to gendered and racialized social norms surrounding womanhood, motherhood, morality, substance use, and criminality, all of which have important implications for women’s engagement with HIV prevention services. Mobile health (mHealth) interventions and interventions that target intersectional stigma have the potential to increase HIV prevention service engagement, but there is a dearth of interventions tailored toward racially diverse WWUD. The proposed research will provide Dr. Meyers-Pantele with the training to address this critical gap in HIV prevention research. She will employ qualitative methods to identify key experiences with HIV prevention services and intersectional stigma, and potential barriers and facilitators to intervention adoption and implementation, to inform the development of potential theory-driven mHealth intervention components. This information will be used to develop and test the usability of the mheaLth interventiOn To redUce Stigma (LOTUS) intervention to improve HIV prevention service engagement and intersectional stigma for racially and ethnically diverse WWUD. Lastly, she will conduct a pilot RCT to assess the feasibility, acceptability, and preliminary impact of the LOTUS intervention. This training will uniquely position her as one of few mHealth interventionists specializing in intersectional stigma for WWUD at UCSD.

项目概要/摘要 Meyers-Pantele 博士候选人以独立职业目标申请 K01 指导培训奖 作为一名健康行为干预师，获得富有成效和独立的研究生涯，重点关注 然而，她目前的培训并没有减少吸毒妇女之间的艾滋病毒差异。 超出了对耻辱和物质使用数据的二次分析，不足以进行深入的分析 制定和实施卫生保健所需的理论和实践方法的指导 具体来说，K01 培训将为她提供支持。 通过以下方式过渡为独立职业科学家：(1) 提高交叉理论的熟练程度，以提供信息 针对艾滋病毒预防服务参与和针对不同种族的交叉耻辱的干预措施 WWUD，(2) 获得移动医疗干预设计和开发方面的专业知识，以创建拟议的移动医疗 干预，(3) 提高实施随机对照试验的能力，以试点已开发的 干预，(4) 加强她在实施科学方面的技能基础，以设计具有以下特点的干预措施： 采用和实施的潜力，以及（5）培养必要的个人发展技能 这些培训目标将通过教学课程、培训来实现。 研讨会、参与专业研究网络、实践研究和指导培训。 研究和环境。WWUD 感染 HIV 的风险较高，且预暴露水平较低。 此外，不同种族和民族的 WWUD 经验也不同。 由于围绕女性、母亲、性别和种族的社会规范而产生的交叉耻辱 道德、药物滥用和犯罪行为，所有这些都对妇女参与社会活动产生重要影响 艾滋病毒预防服务。移动医疗（mHealth）干预措施和针对跨部门的干预措施。 耻辱有可能提高艾滋病毒预防服务的参与度，但缺乏干预措施 拟议的研究将为 Meyers-Pantele 博士提供针对种族多元化的 WWUD 的定制。 她将采用定性方法来确定艾滋病毒预防研究中的这一关键差距。 艾滋病毒预防服务和交叉耻辱的主要经验以及潜在的障碍和促进因素 干预措施的采用和实施，为潜在理论驱动的移动医疗的发展提供信息 该信息将用于开发和测试健康的可用性。 干预减少耻辱 (LOTUS) 干预以提高艾滋病毒预防服务的参与度和 最后，她将进行一项试点随机对照试验来评估。 LOTUS 干预的可行性、可接受性和初步影响将是独一无二的。 将她定位为加州大学圣地亚哥分校为数不多的专门研究 WWUD 交叉污名的移动医疗干预专家之一。