Peru Vanderbilt – PREvention through VacciNation Training (PREVENT) program

秘鲁范德比尔特 — 通过疫苗接种培训进行预防 (PREVENT) 计划

• 批准号: 10674393
• 负责人: CARLOS G GRIJALVA
• 金额: $ 25.14万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2027-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10674393
• 关键词: Academic Medical Centers; Address; Authorization documentation; Biological; Communicable Diseases; Data; Developing Countries; Development; Disease; Doctor of Philosophy; Ensure; Evaluation; Faculty; Fellowship; Future; Goals; Grant; Growth; Herd Immunity; Immunization Programs; Knowledge; Lead; Mentors; Modernization; Peru; Pharmacoepidemiology; Prevention; Process; Productivity; Program Evaluation; Research; Research Personnel; Scientist; Structure; Technical Expertise; Training; Training Programs; Vaccination; Vaccines; antimicrobial resistant infection; authority; distrust; implementation evaluation; low and middle-income countries; multidisciplinary; pressure; programs; success; tool; unvaccinated; vaccine development; vaccine trial; vaccinology

SUMMARY While vaccination is the most efficient tool for the prevention of infectious diseases both in developed and developing countries, the implementation of effective vaccination programs is challenging. The development, introduction and implementation of effective vaccination depends on availability of locally generated evidence, especially data required by local regulatory authorities. An essential requirement to make this happen is to have well-trained local researchers who have a clear understanding of the process behind vaccine development, vaccine introduction and program implementation. Training of researchers on the achieved impact of vaccination on antimicrobial resistant infections, the relevance of indirect protection and the biological pressure induced by vaccination programs are examples of well-established vaccination topics that are commonly overlooked. A proper understanding of the effects of vaccination on unvaccinated groups through indirect or herd immunity is crucial, but this is frequently misinterpreted. Moreover, there is a growing distrust in vaccines and vaccination programs that needs to be addressed by researchers with appropriate technical skills. Thus, there is a growing global need for training in vaccinology and the study of vaccine-preventable diseases encompassing the entire process from vaccine development to field implementation and program evaluation. To address these needs, Vanderbilt University Medical Center (VUMC), the Instituto de Investigacion Nutricional (IIN) and the Universidad Peruana Cayetano Heredia (UPCH) are joining forces to build the Peru-Vanderbilt Prevention through Vaccination Training Program (PREVENT). The overall goal of PREVENT is to develop a cadre of researchers and educators equipped with modern knowledge and expertise to lead vaccine preventable diseases research and training in Peru and to encourage US-based researchers to engage in vaccination research in low- and middle-income country (LMICs). PREVENT builds on the very successful 14-year Research Partnership with the IIN and UPCH and on the Vanderbilt Vaccine Training and Evaluation Unit and the Division of Pharmacoepidemiology's expertise in the study of vaccine preventable diseases, training and mentoring. PREVENT will support 10 medium-long term trainees (Master's, PhD and faculty fellowships). Specifically, PREVENT aims to 1) Train a cadre of researchers and educators (trainers) to conduct multidisciplinary vaccine preventable diseases research and build training capacity in Peru; 2) Train scientists and future leaders in vaccine-preventable diseases research in Peru; and, 3) Ensure and document PREVENT's long-term impact. The ongoing IIN/UPCH-Vanderbilt Research Partnership has proven highly productive and successful. A new training program focusing on Vaccinology and the study of vaccine preventable diseases and the growth of structures and efforts to increase grant success will move IIN and UPCH toward a new horizon in vaccine preventable diseases and address Peru's need for a world-class workforce trained in vaccinology.

概括 疫苗接种是预防发达和预防传染病的最有效工具 发展中国家，实施有效的疫苗接种计划是具有挑战性的。发展， 介绍和实施有效疫苗接种取决于当地生成的证据的可用性， 特别是地方监管机构所需的数据。实现这一目标的基本要求是 让训练有素的本地研究人员对疫苗背后的过程有清晰的了解 开发，疫苗引入和计划实施。培训研究人员的成就 疫苗接种对抗菌抗性感染的影响，间接保护的相关性和生物学 疫苗接种计划引起的压力是公认的疫苗接种主题的例子 通常被忽略。通过正确理解疫苗接种对未接种群体的影响 间接或牛群免疫至关重要，但这常常被误解。而且，对 疫苗和疫苗接种计划需要由适当技术的研究人员解决 技能。因此，全球对疫苗学培训的需求越来越大，可预防疫苗的研究 从疫苗开发到现场实施和计划的整个过程的疾病 评估。为了满足这些需求，范德比尔特大学医学中心（VUMC），Instituto de Nutricialition（IIN）和Peruana Cayetano Heredia大学（UPCH）正在与 通过疫苗接种培训计划（预防）来建立秘鲁 - 弗兰德比尔特的预防。总体目标 预防是开发一群具有现代知识和专业知识的研究人员和教育工作者 在秘鲁领导可预防疾病的疫苗研究和培训，并鼓励美国的研究人员 在低收入国家（LMIC）进行疫苗接种研究。防止在当时建立 成功与IIN和UPCH以及Vanderbilt疫苗培训的14年研究合作伙伴关系以及 评估单位和药物ePIDEMIOLOGY在可预防疫苗研究方面的专业知识 疾病，培训和指导。预防将支持10个中期学期学员（硕士，博士和 教师奖学金）。具体而言，防止目标1）培训一群研究人员和教育工作者（培训师） 进行多学科疫苗可预防疾病研究并在秘鲁建立培训能力； 2）火车 秘鲁的可预防疾病研究的科学家和未来领导者； 3）确保和文件 防止长期影响。正在进行的IIN/UPCH-Vanderbilt研究合作伙伴关系已被证明很高 富有成效和成功。一项针对疫苗学和疫苗研究的新培训计划 可预防的疾病以及结构的成长以及增加授予成功的努力将使IIN和 UPCH向疫苗预防疾病的新视野，并满足秘鲁对世界一流的需求 接受疫苗学培训的劳动力。