2023 Excitatory Synapses and Brain Function Gordon Research Conference and Seminar

2023兴奋性突触与大脑功能戈登研究会议暨研讨会

• 批准号: 10673318
• 负责人: PABLO E CASTILLO
• 金额: $ 2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-15 至 2023-07-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10673318
• 关键词: Address; Age; Alzheimer' s Disease; Atmosphere; Back; Basic Science; Behavior; Biological; Biology; Brain; Brain Diseases; Cells; Collaborations; Communication; Country; Development; Discipline; Disease; Dissection; Drug Addiction; Drug Prescriptions; Ensure; Environment; Epilepsy; Ethnic Origin; Event; Excitatory Synapse; Faculty; Fostering; Future; Gender; Genes; Goals; Injury; Knowledge; Learning; Link; Location; Mental Depression; Mental disorders; Mentors; Methods; Mission; Molecular; N-Methyl-D-Aspartate Receptors; National Institute of Child Health and Human Development; National Institute of Drug Abuse; National Institute of Mental Health; National Institute of Neurological Disorders and Stroke; Nationalities; Neurons; Neurosciences; Oral; Parkinson Disease; Participant; Postdoctoral Fellow; Process; Regulation; Request for Proposals; Research; Research Personnel; Role; Schizophrenia; Science; Scientist; Senior Scientist; Shapes; Signal Transduction; Specific qualifier value; Stroke; Structure; Switzerland; Synapses; Synaptic Transmission; Technology; Traumatic Brain Injury; Underrepresented Populations; United States National Institutes of Health; autism spectrum disorder; brain shape; career; career development; design; diversity and inclusion; driving force; experience; frontier; graduate student; high standard; imager; innovation; interest; lectures; meetings; memory process; nervous system disorder; neural circuit; novel therapeutic intervention; posters; preservation; programs; social; sound; success; symposium; synaptic function; transmission process

Project Summary This proposal requests partial support for a longstanding, well-attended, and well-received Gordon Research Conference (GRC) on Excitatory Synapses and Brain Function on June 4-9, 2023, at Les Diablerets Conference Center in Switzerland. The GRC will be preceded by a Gordon Research Seminar (GRS) targeted towards graduate students and postdoctoral fellows on June 3-4, 2023, at the same location. Excitatory synapses are functional units that enable rapid signal transmission and communication between neurons. Through these connections, neurons establish functional circuits that process information necessary to generate all brain functions. Synapses are the target aberrant synaptic function is causally linked to several neurological and psychiatric disorders, including of many commonly prescribed medications, and schizophrenia, autism, depression, drug addiction, Parkinson's disease, Alzheimer's disease, traumatic brain Understanding the structure and function of excitatory synapses is therefore fundamental not only to infer knowledge about brain function but also to find new therapeutic strategies for brain diseases. The conference will bring together outstanding junior and senior scientists across different disciplines including neuron biologists, anatomists, molecular and developmental biologists, biochemists, cell/molecular imagers, biophysicists and neurophysiologists with the goal of injury, stroke and epilepsy. stimulating discussions about current concepts and defining new challenges for future research. The program includes two keynote lectures and eight sessions that broadly address current issues in synaptic circuit dissection, learning and memory processes, experience- dependent plasticity, technological advances, synaptic basis of the diseases, NMDA receptor structure and function, synaptic specification and development, signaling from synapses to genes and back. In addition, poster sessions will permit all participants to contribute to these topics. Besides the invited speakers, we will select junior scientists from the submitted abstracts for short oral presentations. The program has been designed not only to highlight cutting edge approaches and to stimulate new concepts, methods and technologies within a sound biological framework of fundamental neuroscience, but also to promote underrepresented groups in science. The conference will bring together expert scientists worldwide in an environment that is conducive to discussion and exchange of ideas. The exchange of ideas at this conference has been a driving force for the field. We expect the 2023 GRC on Excitatory Synapses and Brain Function will shape future scientific directions and provide critical support for the mission of NINDS as well as other NIH institutes such as NIDA, NIMH, NICHD and NIA.

项目摘要 该提案要求部分支持长期，有影响力和良好的戈登研究 2023年6月4日至9日在LES Diablerets会议上举行的兴奋性突触和大脑功能会议（GRC） 瑞士中心。 GRC将在针对针对的Gordon研究研讨会（GRS）之前 研究生和博士后研究员于2023年6月3日至4日在同一地点。 兴奋性突触是功能单位，可以快速信号传输和之间的通信 神经元。通过这些连接，神经元建立了功能电路，以处理必要的信息 产生所有大脑功能。突触是目标 异常的突触功能与几种神经和精神疾病有关，包括 在许多常规处方药中，以及 精神分裂症，自闭症，抑郁，吸毒成瘾，帕金森氏病，阿尔茨海默氏病，大脑创伤 因此，了解兴奋性突触的结构和功能是 基本不仅是为了推断有关大脑功能的知识，还可以找到新的脑治疗策略 疾病。会议将汇集不同学科的杰出初级和高级科学家 包括神经元生物学家，解剖学家，分子和发育生物学家，生物化学家，细胞/分子 成像师，生物物理学家和神经生理学家的目标 受伤，中风和癫痫病。 刺激有关当前概念的讨论 并定义未来研究的新挑战。该计划包括两个主题演讲和八个会议 该广泛解决了突触电路解剖，学习和记忆过程中的当前问题，经验 - 依赖的可塑性，技术进步，疾病的突触基础，NMDA受体结构和 功能，突触规范和发育，从突触到基因和背部的信号传导。另外，海报 会议将允许所有参与者为这些主题做出贡献。 除了被邀请的演讲者外，我们还将从提交的摘要中选择初级科学家 演讲。该程序的设计不仅是为了突出最前沿的方法和刺激 基本神经科学的合理生物学框架内的新概念，方法和技术，但 也促进科学中代表性不足的群体。会议将汇集专家科学家 在一个有利于讨论和交流思想交流的环境中。想法的交流 这次会议一直是该领域的驱动力。我们希望2023 GRC在兴奋性突触和 大脑功能将塑造未来的科学方向，并为NIND的使命提供关键的支持 就像其他NIH机构一样，例如NIDA，NIMH，NICHD和NIA。