Bioinformatics Core

生物信息学核心

• 批准号: 10681842
• 负责人: Andrew V Kossenkov
• 金额: $ 2.61万
• 依托单位: WISTAR INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-30 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10681842
• 关键词: Address; Bioinformatics; Characteristics; Combined Modality Therapy; Consultations; Data; Data Analyses; Data Security; Development; Ensure; Environment; Experimental Designs; Generations; Individual; Lead; Manuscripts; Messenger RNA; MicroRNAs; Molecular; Mutation; Pharmacotherapy; Preclinical Testing; Preparation; Process; Protocols documentation; Quality Control; Reporting; Research; Research Design; Research Personnel; Research Proposals; Sample Size; Statistical Data Interpretation; Time; Writing; data management; experimental study; melanoma; member; preclinical study; programs; protein expression; transcriptome sequencing; treatment response

Project Summary – Bioinformatics Core The Bioinformatics Core, will conduct bioinformatics and statistical analyses of data generated by Projects and Cores to address research hypotheses defined in the project-specific proposals as well as perform integrative analyses in order to combine data from all experiments. The Core will provide central storage, data management, and information security for generated raw and processed high-throughput data within the PTDC. The Core will assist with preparation and writing of final reports, abstracts, manuscripts, and future research proposals. During the span of the Research Program, Bioinformatics Core will ensure a timely progress tracking of PDX trials and sharing of generated results between members of PTDC.

项目摘要 - 生物信息学核心 生物信息学核心将对项目生成的数据进行生物信息学和统计分析 核心用于解决特定项目提案中定义的研究假设以及执行 综合分析，以便合并所有实验的数据。核心将提供中央存储、数据。 管理和信息安全，以生成原始数据和处理后的高通量数据 PTDC。核心将协助准备和撰写最终报告、摘要、手稿和未来的报告。 在研究计划期间，生物信息学核心将确保及时提出研究提案。 跟踪 PDX 试验的进度并在 PTDC 成员之间共享生成的结果。