Developing and testing the Opioid Rapid Response System

开发和测试阿片类药物快速反应系统

• 批准号: 10696992
• 负责人: Hye Jeong Choi
• 金额: $ 85.88万
• 依托单位: REAL PREVENTION, LLC
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10696992
• 关键词: Address; Behavioral; Behavioral Model; Cardiac; Cessation of life; Communication; Communities; Community Networks; County; Data; Dedications; Development; Effectiveness of Interventions; Electronic Mail; Emergency Situation; Emergency response; Event; Evidence based program; Expenditure; Focus Groups; Goals; Health; Health Personnel; Health Promotion; Indiana; Individual; Innovation Corps; Interview; Knowledge; Life; Link; Literature; Marketing; Medical; Medical emergency; Modeling; Multimedia; Naloxone; Naloxone Training; Nature; Online Systems; Opioid; Overdose; Overdose reversal; Participant; Performance; Persons; Phase; Pilot Projects; Prevention; Procedures; Protocols documentation; Public Health; Reaction Time; Readiness; Recovery; Research; Resources; Rural; Sampling; Science; Small Business Innovation Research Grant; Societies; Standardization; Stroke; Suicide; System; Technology; Testing; Training; Training Programs; Urban Community; Work; base; behavior change; behavioral outcome; commercialization; commune; communication theory; comparative efficacy; cost; cost effective; design; digital; digital intervention; dissemination strategy; effectiveness evaluation; emergency service responder; evidence base; implementation science; improved; innovation; innovative technologies; lens; multimodality; opioid epidemic; opioid mortality; opioid overdose; prototype; psychological outcomes; randomized trial; randomized, clinical trials; recruit; response; rural area; social cognitive theory; social group; social influence; social media; social stigma; theories; urban setting; usability; web site

Abstract This Phase II SBIR will develop and demonstrate the efficacy of the Opioid Rapid Response System (ORRS) to improve responses to opioid overdoses. Opioid overdoses exact a tremendous cost in lives and expenditures. Naloxone has been developed to counteract overdoses; however, the nature of these events requires a rapid response, a situation that challenges emergency responders in both lightly populated rural areas as well as densely populated urban communities. Apps now exist with the potential to obviate timing concerns by linking lay citizen responders to events through the 911 system. One such app, PulsePoint, is already in place in 4,100 communities throughout the U.S. for cardiac events, while two other potential partners, OpiSafe and Brave, focus on overdoses and have expanding customer bases. Other communities simply distribute naloxone as widely as possible. Neither naloxone distribution nor the apps can accomplish their goals without effectively recruiting and training many citizen responders who are both able to administer life-saving naloxone and confident in their ability to do so. To date, there are no evidence-based programs to accomplish these goals. This project is designed to develop innovative and effective recruitment and training strategies to fill this gap. ORRS was based on a pilot project demonstrating that lay citizen responders could utilize the PulsePoint app to respond to overdose events. In Phase I, we developed an effective recruitment protocol based on identity theory that uses appeals to individuals (personal identity appeals) and others (communal appeals) and administered it through multi-modalities. We also developed a prototype of ORRS online training and demonstrated usability and feasibility through a study in five Indiana counties. In Phase II, ORRS recruitment will be refined to improve the performance of the social media component, the training platform will be enhanced to focus on CPR and stigma reduction as well as enhanced engagement, and a national RCT will be conducted in 8 communities. Recruitment and training effects on psychological and behavioral outcomes will be evaluated. The project has great promise for rapid and wide dissemination through the PulsePoint, OpiSafe, and Brave Technology Coop networks of communities as well as public health departments. The project has the potential to develop a model for community responses to similar public health events.

抽象的 该II期SBIR将开发并证明阿片类药物快速反应系统（ORR）对 改善对阿片类药物过量的反应。阿片类药物过量服用了生活和支出的巨大成本。 纳洛酮已经开发出来抵消过量药物。但是，这些事件的性质需要迅速 响应，这种情况挑战了人口稠密的农村地区以及 人口稠密的城市社区。现在存在应用程序，有可能通过链接来消除时机问题 外行公民通过911系统对事件的响应者。一个这样的应用程序PulsePoint已经在4,100中已经存在 美国各地的社区进行心脏事件，而另外两个潜在的伙伴Opisafe and Brave， 专注于过量服用并具有扩大的客户基础。其他社区只是将纳洛酮作为 尽可能广泛。纳洛酮分布和应用程序都不能无效地实现目标 招募和培训许多能够管理挽救生命的纳洛酮和的公民响应者 对他们这样做的能力充满信心。迄今为止，还没有基于证据的计划来实现这些目标。 该项目旨在制定创新有效的招聘和培训策略来填补这一空白。 ORR是基于一个试点项目，表明外行公民响应者可以将Pulsepoint应用程序用于 响应过量的事件。在第一阶段，我们根据身份理论制定了有效的招聘协议 它使用对个人（个人身份上诉）和其他人（公共上诉）的吸引力并管理 通过多模式。我们还开发了ORRS在线培训的原型，并证明了可用性 以及通过在五个印第安纳州的研究中的可行性。在第二阶段，ORRS的招聘将被完善 提高社交媒体组件的性能，将增强培训平台以专注于 CPR和污名的减少以及增强的参与度，以及8号国家RCT 社区。将评估对心理和行为结果的招聘和培训影响。 该项目在通过Pulsepoint，Opisafe和Brave的快速和广泛传播方面有很大的希望 社区和公共卫生部门的技术库库网络。该项目有潜力 开发一个模型，以对类似的公共卫生事件进行反应。