Biostatistics and Bioinformatics Shared Resources

生物统计学和生物信息学共享资源

基本信息

批准号：
10670839
负责人：
Xi Steven Chen
金额：
$ 22.18万
依托单位：
UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-10 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10670839
关键词：
Applications Grants Basic Science Bioinformatics Bioinformatics Shared Resource Biometry Biostatistics Shared Resource Biotechnology Calendar Cancer Center Support Grant Clinical Clinical Sciences Clinical Trials Clinical Trials Design Collaborations Comprehensive Cancer Center Consultations Data Data Analyses Education Educational process of instructing Ensure Extramural Activities Faculty Funding Funding Opportunities Grant Laboratories Malignant Neoplasms Manuscripts Mentors Methodology Methods Monitor National Cancer Institute Peer Review Phase Population Research Population Sciences Preparation Protocols documentation Publications Reporting Research Research Design Research Personnel Resource Sharing Resources Safety Sample Size Science Services Statistical Computing Training and Education anticancer research data acquisition experience member novel population based power analysis programs research study success tool

项目摘要

PROJECT SUMMARY: BIOSTATISTICS AND BIOINFORMATICS SHARED RESOURCE The Biostatistics and Bioinformatics Shared Resource (BBSR) provides Sylvester Comprehensive Cancer Center (Sylvester) investigators access to contemporary biostatistics, bioinformatics, and computational expertise in support of clinical trials as well as laboratory- and population-based cancer research studies. This critical, highly utilized shared resource contributes to all phases of research, including study design, data analysis and interpretation, and education in quantitative science methods and application tools. Over the past three years, the BBSR has greatly expanded its accessibility, capacity, and breadth and now comprises a Director (with expertise in both biostatistics and bioinformatics), four biostatisticians, and three bioinformaticians. Advances in biotechnologies and computing have significantly increased the need for the sophisticated statistical methodologies provided by the resource and BBSR faculty and staff have extensive cancer-specific experience and expertise. BBSR staff are readily available to Sylvester investigators, participate regularly in all three research programs, and engage other shared resource leaders to ensure comprehensive and seamless support for Sylvester members. The BBSR provided services to 60 Sylvester members in calendar year 2017 (77% of which had peer-reviewed funding), which comprised 65% of BBSR usage. The BBSR serves a critical need for Sylvester, ensuring statistical validity of research across the continuum from grant applications to basic, clinical, translational and population-based research to peer- reviewed publications.

项目摘要：生物统计学和生物信息学共享资源生物统计学和生物信息学共享资源 (BBSR) 提供西尔维斯特综合癌症中心（西尔维斯特）研究人员接触当代生物统计学、生物信息学和计算支持临床试验以及基于实验室和人群的癌症研究的专业知识。这关键的、高度利用的共享资源有助于研究的所有阶段，包括研究设计、数据分析和解释，以及定量科学方法和应用工具的教育。过去的事三年来，BBSR 极大地扩展了其可及性、容量和广度，现在包括主任（具有生物统计学和生物信息学方面的专业知识）、四名生物统计学家和三名生物统计学家生物信息学家。生物技术和计算的进步显着增加了对资源提供的复杂统计方法和 BBSR 教职员工拥有广泛的癌症特定的经验和专业知识。西尔维斯特调查人员可以随时联系 BBSR 工作人员，定期参与所有三个研究计划，并与其他共享资源领导者合作，以确保为西尔维斯特会员提供全面、无缝的支持。 BBSR 为 60 Sylvester 提供服务 2017 日历年的成员（其中 77% 获得同行评审资金），其中 BBSR 占 65% 用法。 BBSR 满足了 Sylvester 的关键需求，确保整个研究的统计有效性从拨款申请到基础、临床、转化和基于人群的研究，再到同行研究的连续统一体审查出版物。