Training Program in Cardiac Innovation

心脏创新培训计划

基本信息

批准号：
10666505
负责人：
Peter A Crawford
金额：
$ 17.56万
依托单位：
UNIVERSITY OF MINNESOTA
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-01 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10666505
关键词：
Cardiac Training Programs innovation

项目摘要

Project Summary Cardiovascular disease in the American population is continuously a major source of debilitation and death despite increased prevention, diagnostic, and treatment options. This situation calls for increased scientific understanding and innovative application of these findings to the care of patients in order to prevent or cure heart disease. This training program in cardiovascular innovation is designed to teach the scientific and technical skills necessary to develop a novel idea and carry this idea through to proof of concept in man. The training program takes unique advantage of the strengths of the Lillehei Heart Institute, the University of Minnesota Cardiovascular Division, the wider community of translational medicine and entrepreneurship at the University of Minnesota, and the Twin Cities biotech, pharma, and device industries. This application will train basic and clinical scientists in an interdisciplinary environment with the goal of giving them the insight and tools to be able to successfully carry an idea from conception to implementation in man. Therefore, the major goal of this new Training Program is to provide an interdisciplinary research and training environment wherein trainees will be exposed to the continuum of technological development from conceptual idea to testing at the basic, small animal, large animal, and human levels. Trainees will be advantaged by community strengths in basic, translational, and clinical science, training in cardiovascular innovation and entrepreneurship, and industry interactions and mentorship. There are several unique features of this training program: 1) a focus on cardiovascular sciences, 2) scientific qualification of its Trainers, 3) curriculum focused on innovation, 4) presence of industry mentors, and 5) an opportunity for meaningful industry interactions. The program will consist of a basic cardiovascular curriculum augmented by specific training in cardiovascular innovation. Each trainee will be required to participate in the Bakken Innovation Fellows Program. The goal of this program is to train the next leaders in medtech by fostering leadership and teaching risk management for medical innovations. Trainees will also partake of the Carlson School of Management Medical Industry Leadership Institute (MILI) program. MILI offers students innovative training, knowledge, and experiences through industry-specific courses and unique, hands-on evaluations of emerging technologies from around the globe. Trainees will be required to take 4 relevant half-day courses offered by the Technological Leadership Institute: 1) Innovation, Leadership & Communication, 2) How to Create and Stimulate a Culture of Innovation, 3) Communication in a Technical Environment: Developing Writing and Presenting Skills, and 4) the yearly Innovation Workshop "Becoming a Medical Technology Innovator." Trainees will engage in a minimum of 3 years of research training. The first two years of training will be for innovation and other didactics and for carrying out the research. Year 3 will be dedicated predominantly to developing a business plan related to the project and writing an appropriate grant application for career advancement. For PhDs, this would consist of a K99/R01 award application, and for MD trainees, the application would be for the K08 or K23 programs.

项目概要心血管疾病一直是美国人衰弱和死亡的主要原因尽管预防、诊断和治疗选择有所增加。这种情况需要加强科学了解这些发现并将其创新应用到患者护理中，以预防或治愈心脏病疾病。该心血管创新培训计划旨在教授科学和技术技能开发一个新颖的想法并将该想法应用于人类的概念验证是必要的。培训计划充分利用明尼苏达大学心血管研究所 Lillehei 心脏研究所的优势明尼苏达大学更广泛的转化医学和创业社区，以及双城生物技术、制药和设备行业。该应用程序将培训基础和临床科学家一个跨学科的环境，目标是为他们提供能够成功开展工作的洞察力和工具一个想法从构思到在人身上实施。因此，这个新培训计划的主要目标是提供跨学科的研究和培训环境，使受训者能够接触到连续体技术发展从概念想法到基础、小动物、大型动物和人类的测试水平。受训者将受益于社区在基础、转化和临床科学、培训方面的优势心血管创新和创业，以及行业互动和指导。有几个该培训计划的独特之处：1) 重点关注心血管科学，2) 其科学资质培训师，3）专注于创新的课程，4）行业导师的存在，以及 5）机会有意义的行业互动。该计划将包括基础心血管课程，并辅以心血管创新方面的具体培训。每个学员都需要参加巴肯创新研究员计划。该计划的目标是通过培养领导力和能力来培训医疗技术领域的下一代领导者教授医疗创新的风险管理。学员还将参加卡尔森学院管理医疗行业领导学院 (MILI) 计划。 MILI为学生提供创新培训，通过针对特定行业的课程以及对新兴行业的独特实践评估，获得知识和经验来自全球各地的技术。学员将被要求参加由学院提供的 4 门相关的半日制课程技术领导力学院：1）创新、领导力和沟通，2）如何创造和激励创新文化，3）技术环境中的沟通：培养写作和表达技巧， 4) 年度创新研讨会“成为医疗技术创新者”。学员将参与至少 3 年的研究培训。前两年的培训将用于创新和其他教学并进行研究。第三年将主要致力于制定相关的商业计划参与该项目并撰写适当的职业发展资助申请。对于博士来说，这包括 K99/R01 奖励申请，对于 MD 学员，申请将适用于 K08 或 K23 计划。

项目成果

期刊论文数量（3）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Concomitant Respiratory Failure Can Impair Myocardial Oxygenation in Patients with Acute Cardiogenic Shock Supported by VA-ECMO.

DOI：
10.1007/s12265-021-10110-2
发表时间：
2022-04
期刊：
Journal of cardiovascular translational research
影响因子：
3.4
作者：
Prisco AR;Aguado-Sierra J;Butakoff C;Vazquez M;Houzeaux G;Eguzkitza B;Bartos JA;Yannopoulos D;Raveendran G;Holm M;Iles T;Mahr C;Iaizzo PA
通讯作者：
Iaizzo PA

2021 American Thoracic Society BEAR Cage Winning Proposal: Microbiome Transplant in Pulmonary Arterial Hypertension.