Training in Cell and Molecular Biology

细胞和分子生物学培训

基本信息

批准号：
10631060
负责人：
Bryce Paschal
金额：
$ 42.44万
依托单位：
UNIVERSITY OF VIRGINIA
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-07-01 至 2026-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10631060
关键词：
Cellular biology Molecular Biology Training

项目摘要

Abstract The University of Virginia is consistently ranked within the top 3 public universities and has a traditional strength in the areas of cell and molecular biology, where it had discoveries as central as the mechanism of G-protein signaling, development of the histone code concept and the identification of Map Kinase. For 35 years the interdisciplinary Cell and Molecular Biology Graduate Program (CMB), whose 86 faculty from 12 departments and three schools, has been bringing together the best biomedical graduate students and faculty from across the grounds to generate a training forum that complements classroom and laboratory experience. Students join an inclusive program in their second year and remain associated with the program until they graduate. The training focuses on the second and third years of Ph.D. training employing tools that guide students through the transition from class knowledge to independent thinking and practical use of the scientific method. The CMB program intensifies this transformative period by nurturing the students through a series of poster sessions, data clubs, retreats, writing classes, mixers, and symposia to expose the students to outstanding multi- disciplinary science from around the university. The program also builds professional skills through mentor training, workshops on both scientific rigor and reproducibility and ethics, volunteer opportunities in the Charlottesville community, and consistent exposure to emerging topics that affect the biomedical community. Our goal is well rounded PhD trainees that can both employ the scientific method to complex problems and also master the professional skills required for the numerous scientific career choices of the 21st century. The past success of our trainees in both academic and nonacademic scientific careers demonstrates that the CMB program prepares students to become leaders of biomedical sciences.

抽象的弗吉尼亚大学一直位居公立大学前三名，并拥有传统的在细胞和分子生物学领域的实力，它在这些领域的发现与 G 蛋白信号传导机制、组蛋白密码概念的发展以及组蛋白密码的鉴定映射激酶。 35 年来，跨学科细胞和分子生物学研究生项目 (CMB)，其来自 12 个系和 3 个学院的 86 名教职员工汇聚了最优秀的人才来自各地的生物医学研究生和教师创建一个培训论坛补充课堂和实验室经验。学生在第二次参加包容性课程一年并保持与该计划的联系直到他们毕业。培训重点是第二个和博士学位的第三年。培训使用指导学生完成课堂过渡的工具知识能够独立思考并实际运用科学方法。 CMB计划通过一系列海报会议、数据来培养学生，强化这一变革时期俱乐部、静修会、写作课、混音师和研讨会，让学生接触优秀的多学科知识来自大学各地的学科科学。该计划还通过以下方式培养专业技能：导师培训、关于科学严谨性、可重复性和道德的研讨会、志愿者夏洛茨维尔社区的机会，以及持续接触影响的新兴话题生物医学界。我们的目标是培养全面发展的博士生，他们既能运用科学知识解决复杂问题的方法，并掌握众多科学所需的专业技能 21世纪的职业选择。我们的学员过去在学术和非学术方面的成功科学职业表明，CMB 项目帮助学生成为科学界的领导者生物医学科学。

项目成果

期刊论文数量（19）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Effect of chromatin modifiers on the plasticity and immunogenicity of small-cell lung cancer.

DOI：
10.1038/s12276-022-00905-x
发表时间：
2022-12
期刊：
EXPERIMENTAL AND MOLECULAR MEDICINE
影响因子：
12.8
作者：
Kirk, Nicole A.;Kim, Kee-Beom;Park, Kwon-Sik
通讯作者：
Park, Kwon-Sik

Oxidized cholesterol species as signaling molecules in the brain: diabetes and Alzheimer's disease.

DOI：
10.1042/ns20190068
发表时间：
2019-12-01
期刊：
Neuronal signaling
影响因子：
0
作者：
Weigel, Thaddeus K;Kulas, Joshua A;Ferris, Heather A
通讯作者：
Ferris, Heather A

Non-Canonical Wnt Signaling Regulates Cochlear Outgrowth and Planar Cell Polarity via Gsk3β Inhibition.

DOI：
10.3389/fcell.2021.649830
发表时间：
2021
期刊：
Frontiers in cell and developmental biology
影响因子：
5.5
作者：
Landin Malt A;Clancy S;Hwang D;Liu A;Smith C;Smith M;Hatley M;Clemens C;Lu X
通讯作者：
Lu X

Self-aligned sequential lateral field non-uniformities over channel depth for high throughput dielectrophoretic cell deflection.

DOI：
10.1039/d0lc01211d
发表时间：
2021-03-09
期刊：
Lab on a chip
影响因子：
6.1
作者：
Huang X;Torres-Castro K;Varhue W;Salahi A;Rasin A;Honrado C;Brown A;Guler J;Swami NS
通讯作者：
Swami NS

Regulation of Endosomal Trafficking by Rab7 and Its Effectors in Neurons: Clues from Charcot-Marie-Tooth 2B Disease.