UTMB Clinical and Translational Science Award

UTMB 临床和转化科学奖

• 批准号: 10568556
• 负责人: Randall J Urban
• 金额: $ 7.98万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-18 至 2022-08-01
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10568556
• 关键词: Address; Affect; African American; Age; Characteristics; Clinic; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Network; Clinical and Translational Science Awards; Collaborations; Communication; Communities; Country; Course Content; Data; Discipline of Nursing; Diverse Workforce; Education; Educational Curriculum; Effectiveness; Entrepreneurship; Gender; Geriatrics; Goals; Hand; Health; Health Occupations; Health Sciences; Health system; Healthcare Activity; Heterogeneity; Hispanic; Home; Hospitals; Individual; Institutes; Institution; Institutional Review Boards; Leadership; Learning; Longevity; Medical; Methodology; Methods; Minority; Mission; Modeling; Multi-Institutional Clinical Trial; National Center for Advancing Translational Sciences; Native Americans; Outcomes Research; Participant; Patient Care; Patient-Focused Outcomes; Pediatrics; Phase; Population; Pregnancy; Research; Research Activity; Research Personnel; Research Support; Resource Sharing; Resources; Schools; Science; Services; Special Population; Structure; Technology; Testing; Texas; Training; Training and Infrastructure; Translation Process; Translational Research; Universities; Work; analytical tool; base; career; community engagement; comparative effectiveness; data resource; data sharing; design; effective intervention; effectiveness outcome; experience; health goals; improved; informatics infrastructure; informatics training; innovation; inter-institutional; interoperability; knowledge base; medical schools; meetings; multi-site trial; multidisciplinary; novel; operation; patient population; programs; racial and ethnic; science education; skills; translational pipeline

Contact PD/PI: Urban, Randall J. O. Overall Project Summary The University of Texas Medical Branch (UTMB) has participated as a CTSA hub since 2009. The academic home of our CTSA, the Institute for Translational Sciences (ITS), has brought together multidisciplinary translational teams (MTTs) and the resources necessary to accelerate discoveries toward better health for individuals and communities. Building on our existing strengths, CTSA initiatives have transformed UTMB’s learning and research culture to one that embraces multidisciplinary translational team (MTT) approaches to addressing significant health problems. We have developed novel educational curricula, significant clinical research programs in special populations with multisite clinical trials, and provided leadership in the Texas Regional CTSA consortium (TRCC) and nationally. UTMB’s CTSA hub supports the health goals of the nation by generating, testing and disseminating integrative team science, education and best practices through stakeholder involvement at all stages. Managed by a continuous improvement model using an Innovation Scorecard, we will address six specific aims, to: 1) Expand the knowledge base and practice of collaborative teams to advance the conduct of translational research through team-based innovation. Building on our team science leadership, we will test, learn, and disseminate multi-institutional teaming to enhance the quality, efficiency, effectiveness, and diversity of clinical and translational research. 2) Engage local, regional, and national stakeholders to make research more effective at meeting their needs. We will build upon our relationships to extend inter-institutional partnerships, and to work with stakeholders to disseminate scientific findings and advance the field of community engagement. 3) Harness the potential of harmonized large data platforms across the translational spectrum to improve research efficiency, develop technologies to support research teams, and share resources with researchers across the CTSA network. Our aims are designed to enhance our informatics infrastructure and training with regional and CTSA network interoperability putting existing and novel analytics tools into the hands of users. 4) Promote clinical and translational research across the lifespan including special populations. We will expand upon our significant strengths in multi-site trials in special populations to proactively engage the NCATS Trial Innovation Network for new trials originating from UTMB. 5) Improve training for a diverse workforce in the authentic skills needed to advance all phases of clinical and translational research. Our integrated U, K, and T programs will include participants with diverse professional and educational experience, as well as diverse age, gender, racial, and ethnic characteristics. 6) Develop and disseminate improved methods and processes for translation from discovery to improved health. We will apply a continuous improvement approach to understand barriers, develop effective interventions, and disseminate improvements in translational science and operations. Page 430 Project Summary/Abstract Contact PD/PI: Urban, Randall J. Narrative UTMB’s CTSA Hub will work with local, regional, and national partners to support translational research and accelerate discoveries toward better health. We will train a diverse workforce and build multidisciplinary teams to conduct efficient, high-quality clinical research across the lifespan that includes understudied populations. We will integrate our research and healthcare activities and will generate, apply and share data and best practices across institutions. Page 431

联系PD/PI：Urban，Randall J. O.总体 项目摘要 德克萨斯大学医学分公司（UTMB）自2009年以来一直担任CTSA枢纽。 在我们的CTSA中，转化科学研究所（ITS）已将多学科翻译汇总在一起 团队（MTTS）以及加速发现为个人和健康健康的必要资源和 社区。 CTSA倡议以我们现有的优势为基础，改变了UTMB的学习和研究 文化对涵盖多学科翻译团队（MTT）的方法来解决重大的文化 健康问题。我们已经开发了新颖的教育课程，重大的临床研究计划 具有多站点临床试验的特殊人群，并在德克萨斯州CTSA联盟中提供领导 （TRCC）和全国。 UTMB的CTSA中心通过产生，测试和 通过利益相关者参与来传播综合团队科学，教育和最佳实践 阶段。通过使用创新记分卡的连续改进模型管理，我们将解决六个 特定目标，至：1）扩大协作团队的知识库和实践以推动行为 通过基于团队的创新进行翻译研究。在我们的团队科学领导下，我们将测试， 学习并传播多机构的团队，以提高质量，效率，有效性和多样性 临床和翻译研究。 2）让地方，地区和国家利益相关者更多地使研究更多 有效满足他们的需求。我们将基于我们的关系来扩展机构间的伙伴关系，并 与利益相关者合作以传播科学发现并推进社区参与的领域。 3） 利用整个翻译光谱的协调大数据平台的潜力以改善研究 效率，开发支持研究团队的技术，并与整个研究人员共享资源 CTSA网络。我们的目标旨在通过区域和 CTSA网络互操作性将现有和新颖的分析工具置于用户手中。 4）促进 包括特殊人群的临床和翻译研究。我们将扩大我们的 在特殊人群的多站点试验中的重要优势，以主动参与NCATS试验创新 来自UTMB的新试验网络。 5）改善潜水员劳动力的培训 需要促进临床和翻译研究的所有阶段。我们集成的U，K和T程序将 包括具有潜水员专业和教育经验的参与者，以及潜水年龄，性别，种族，种族， 和种族特征。 6）开发并传播改进的方法和过程以转换 发现改善健康。我们将采用持续的改进方法来理解障碍，发展 有效的干预措施，并传播转化科学和运营的改进。 第430页 项目摘要/摘要 联系PD/PI：Urban，Randall J. 叙述 UTMB的CTSA枢纽将与地方，地区和国家合作伙伴合作，以支持翻译研究和 加速发现改善健康。我们将培训潜水员的劳动力并建立多学科团队 在整个寿命中进行有效的高质量临床研究，其中包括知识的人群。 我们将整合研究和医疗保健活动，并生成，应用和共享数据以及最佳 跨机构的实践。 第431页