Community-Engaged Research on COVID-19 Testing Among Underserved and/or Vulnerable Populations Phase II

社区参与的针对服务不足和/或弱势群体的 COVID-19 检测研究第二阶段

• 批准号: 10544758
• 负责人: Marianna K Baum
• 金额: $ 110.58万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-01 至 2024-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10544758
• 关键词: Affect; Antibodies; Antibody Formation; Anxiety; Area; Attitude; Behavior; Belief; Black Populations; Black race; CLIA certified; COVID-19; COVID-19 disparity; COVID-19 pandemic; COVID-19 prevention; COVID-19 risk; COVID-19 stress; COVID-19 testing; COVID-19 vaccine; Caring; Case Fatality Rates; Cessation of life; Church; Clinic; Common Data Element; Communities; Community Outreach; Community Participation; Complex; Contact Tracing; County; Data; Data Analyses; Economics; Effectiveness; Environmental Risk Factor; Epidemic; Event; Faith; Faith leader; Florida; Goals; Health; Health Personnel; Healthcare; Hispanic; Hispanic Populations; Hospitalization; Hour; Incidence; Individual; Inequity; Infection; Infrastructure; Interview; Knowledge; Laboratories; Leadership; Longitudinal Studies; Measurable; Mental Depression; Mental Health; Minority; Minority Groups; Neighborhoods; Nurses; Outcome; Participant; Phase; Physicians; Play; Population; Psyche structure; Public Health; Questionnaires; RADx Underserved Populations; Research; Resources; SARS-CoV-2 infection; SARS-CoV-2 transmission; Serology; Seroprevalences; Site; Social Conditions; Social status; Source; Surveys; Testing; Underserved Population; United States; Vaccination; Vaccines; Variant; Vulnerable Populations; community engaged research; community engagement; community organizations; community partnership; community transmission; data mining; disparity reduction; ethnic minority; experience; fighting; follow-up; health disparity; hispanic community; improved; member; minority communities; minority health; minority healthcare; outreach; pandemic disease; phase 1 study; poor health outcome; racial minority; recruit; resilience; response; social health determinants; social vulnerability; testing uptake; trustworthiness; underserved community; uptake; vaccine acceptance; vaccine access; vaccine trial; vulnerable community

PROJECT SUMMARY The COVID-19 pandemic has caused unprecedented public health and economic consequences globally and in the United States. Long-standing social inequities have been magnified and vulnerable communities have been disproportionately burdened by the pandemic. In Miami-Dade County, Florida, where minority populations experience a high level of social vulnerability, Blacks and Hispanics are overrepresented in COVID-19 related hospitalizations and deaths compared to national rates. Further, Miami-Dade County continues to experience COVID-19 rates well above the state and national levels. Effective vaccines are now available, yet vaccination rates have been persistently lower among U.S. minorities, broadening disparities in COVID-19 outcomes. As such, expanded SARS-CoV-2 testing and vaccine acceptance is critical to mitigating community spread in underserved and vulnerable communities. In this application for Phase II of the RADx-UP project, we will apply the knowledge gained during Phase I to expand community outreach to increase testing and vaccine uptake in minority communities to decrease disparities that contribute to burden of COVID-19 in underserved and vulnerable populations. We propose to continue our RADx-UP community-engaged research by employing new recruitment strategies in conjunction with four community partners to increase reach of testing that include engaging faith leaders and minority health care providers, and placing our mobile testing (and vaccination) unit in church parking areas. We will also conduct a longitudinal study among participants who completed Phase I of the study to assess (a) changes in infection and vaccination status, (b) how the availability of vaccines affects attitudes, beliefs, and behaviors related to testing, (c) changes in SDoH and their impact on COVID-19 testing and vaccine uptake/hesitancy, and (d) the relationship between mental resilience, mental health, and testing and vaccine uptake/hesitancy, and (e) other RADx-UP common data elements. We will also conduct post-infection and post-vaccination studies on antibody production and subsequent infections. For the proposed Phase II application, we have partnered with new community organizations, including Keeping the Faith to Fight COVID-19, an organization of minority health care providers working with Black and Black Hispanic churches, and with the Community Engagement Alliance (CEAL) Against COVID-19 Disparities initiative. We are currently conducting RADx-UP Phase I with established infrastructure and community partnerships to accomplish the aims and enable rapid and measurable impact in access and uptake of SARS- CoV-2 testing by underserved and vulnerable populations. Our community partners have the resources to provide community engagement, public health mitigation, and follow-up care for cases who test positive. Our strategy includes Scientific and Community Advisory Boards; a mobile testing unit; a CLIA-licensed laboratory headed by the PI of this application; data mining and longitudinal approaches for data analyses; and a research team experienced in recruiting and retaining members of the communities targeted in this proposal.

项目摘要 共同19-19大流行在全球范围内造成了前所未有的公共卫生和经济后果 在美国。长期存在的社会不平等已被放大，脆弱的社区已经 受到大流行的负担不成比例。在佛罗里达州迈阿密戴德县，那里的少数民族人口 在Covid-19相关的情况下，黑人和西班牙裔经历了高度的社会脆弱性，黑人和西班牙裔的人数过多 与国家率相比，住院和死亡。此外，迈阿密戴德县继续经历 Covid-19比率远高于州和国家一级。有效的疫苗现已可用，但疫苗接种 在美国少数民族中，比率持续较低，扩大了19个结果的差异。作为 这样，扩大的SARS-COV-2测试和疫苗接受度对于减轻社区传播至关重要 服务不足和脆弱的社区。在RADX-UP项目的第二阶段申请中，我们将申请 在第一阶段获得的知识扩大社区宣传以增加测试和疫苗的吸收 少数民族社区以减少造成COVID-19的负担的差异，在服务不足和 脆弱的人群。我们建议通过采用 新的招聘策略与四个社区合作伙伴结合 吸引信仰领袖和少数族裔医疗保健提供者，并放置我们的移动测试（和疫苗接种）部门 在教堂停车场。我们还将对完成I期的参与者进行纵向研究 评估（a）感染和疫苗接种状况变化的研究中，（b）疫苗的可用性如何 影响与测试有关的态度，信念和行为，（c）SDOH的变化及其对COVID-19的影响 测试和疫苗的吸收/犹豫，以及（d）心理弹性，心理健康与 测试和疫苗的吸收/犹豫，以及（e）其他RADX-UP通用数据元素。我们还将进行 感染后和疫苗后研究抗体产生和随后的感染。为了 拟议的第二阶段申请，我们与新的社区组织合作，包括保持 信仰与黑人和黑人合作的少数族裔医疗保健提供者的组织，这 西班牙裔教会，以及社区参与联盟（CEAL），反对COVID-19 倡议。我们目前正在通过建立的基础设施和社区进行RADX-UP I阶段 实现目标的合作伙伴关系，并对SARS的访问和吸收产生快速，可衡量的影响 - 通过服务不足和弱势群体进行的COV-2测试。我们的社区合作伙伴有资源 为测试阳性的案件提供社区参与，缓解公共卫生和后续护理。我们的 策略包括科学和社区咨询委员会；移动测试单元； CLIA许可的实验室 由本申请的PI领导；数据挖掘和纵向方法用于数据分析；和 研究团队在该提案中针对的社区招募和保留成员经验丰富。

项目成果

Detection of SARS-CoV-2 in high-efficiency particulate air (HEPA) filters of low-cost air purifiers in community-based organizations.

• DOI: 10.1007/s10661-023-11950-y
• 发表时间: 2023-10-14
• 期刊: Environmental monitoring and assessment
• 影响因子: 3