Administration and Coordination Core

行政及协调核心

• 批准号: 10539322
• 负责人: Vadim Backman
• 金额: $ 23.88万
• 依托单位: NORTHWESTERN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-12-10 至 2026-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10539322
• 关键词: Administrator; Advocate; Award; Back; Beds; Biomedical Engineering; Biomedical Research; Cancer Biology; Cancer Center; Cancer Patient; Chromatin; Collaborations; Communication; Communities; Comprehensive Cancer Center; Decision Making; Development; Educational workshop; Engineering; Ensure; Equity; Evaluation; Event; Fostering; Funding; Goals; Human Resources; Image; Imaging Techniques; Infrastructure; Knowledge; Leadership; Malignant Neoplasms; Mission; Modeling; Monitor; Patients; Process; Program Evaluation; Publications; Quality Control; Recommendation; Records; Reporting; Reproducibility; Research; Research Personnel; Research Project Grants; Resource Allocation; Resource Sharing; Resources; Schedule; Schools; Site Visit; Specialist; Techniques; Testing; Training; Underrepresented Minority; Universities; Validation; Veterans; Work; anticancer research; cancer imaging; cancer stem cell; cancer therapy; data quality; data sharing; design; diversity and equity; diversity and inclusion; equity, diversity, and inclusion; experience; graduate school; improved; innovation; medical schools; meetings; member; minority health; molecular modeling; nanoimaging; programs; recruit; research data dissemination; synergism; technology development; technology research and development; tumor progression; web site

Administrative and Coordination Core: PROJECT SUMMARY The proposed Northwestern University Center for Chromatin NanoImaging in Cancer (NU-CCNIC) will bring together leading cancer research biologists from the Robert H. Lurie Comprehensive Cancer Center in the Feinberg School of Medicine and world-renowned imaging and molecular modeling specialists from the McCormick School of Engineering with the goal of facilitating innovation and application of cutting-edge imaging techniques to help solve some of the most pressing problems in cancer biology research. The Administrative and Coordination Core (ACC) will be led by PI Vadim Backman. The day-to-day administration of the NU-CCNIC will be managed by the Center Administrator, who will be responsible for maintaining all records relative to this award and ensuring communication, synergy, and resource sharing across the NU-CCNIC. Additionally, Center administration will be supported by a Program Manager, who, in collaboration with the Center Administrator, will be responsible for the development of the NU-CCNIC website, scheduling meetings and events, facilitating the sharing of resources, determine whether there will be pre-publication data sharing across the NU-CCNIC, and aid in conversations about data quality control, cross validation, and reproducibility. An External Advisory Panel (EAP) will be formed, bringing together investigators with expertise in fields related to cancer stem cell plasticity and chromatin nanoimaging. The EAP is envisioned as a group of highly active members engaged to advise the NU-CCNIC leadership on scientific direction and review progress evaluation, research strategies and implementation, leadership and dissemination, all in the effort to maximize the impact of the NU-CCNIC. The NU-CCNIC will enhance the translational value and potential impact of its research by engaging a Cancer Research Advocate, who will be a member of the EAP and will be invited to attend NU-CCNIC workshops and site visits. The ACC will support weekly, bi-weekly, monthly, and quarterly research meetings to foster communication, collaboration and integration of the NU-CCNIC and will further support communication and wide- reaching knowledge dissemination through bi-annual workshops with outside speakers. In Aim 1, the Administrative Core will promote and ensure clear and effective communication across the Technology Development (TECH) and Research Test-Bed (RTB) Units. In Aim 2, we will plan and establish regular Center meetings and research workshops to foster communications within the NU-CCNIC and to the broader community that are critical to our research mission and dissemination. In Aim 3, we will work to increase representation and training of underrepresented minorities in the biomedical research workforce of the NU-CCNIC. In Aim 4, we will partner with the cancer research advocate to ensure the critical importance of the patient perspective in the NU- CCNIC. In Aim 5, we will work with the EAP and Cancer Research Advocate on NU-CCNIC evaluation programs to ensure Center progress is accomplished on a timely basis and that resources are allocated judiciously.

行政与协调核心：项目摘要 拟议的西北大学染色质纳米影像中心（NU-CCNIC）将带来 来自罗伯特·H·卢里（Robert H. Lurie）综合癌症中心的领先癌症研究生物学家 Feinberg医学院和世界知名的成像和分子建模专家 麦考密克工程学院的目的是促进创新和尖端成像的应用 帮助解决癌症生物学研究中一些最紧迫的问题的技术。行政 Pi Vadim Backman将领导协调核心（ACC）。 NU-CCNIC的日常管理 将由中心管理员管理，他们将负责维护所有相对于此的记录 授予并确保整个NU-CCNIC的沟通，协同作用和资源共享。另外，中心 行政管理人员将得到计划经理的支持，该计划经理将与中心管理员合作 负责开发NU-CCNIC网站，安排会议和活动，促进 共享资源，确定是否会在整个NU-CCNIC中进行出版前数据共享，以及 帮助有关数据质量控制，交叉验证和可重复性的对话。外部咨询面板 （EAP）将形成，将与癌症干细胞可塑性有关的研究人员组合在一起 和染色质纳米影像。 EAP被设想为一群高度活跃的成员，以建议 NU-CCNIC在科学方向和审查进度评估，研究策略和 实施，领导和传播都是为了最大程度地发挥NU-CCNIC的影响。这 NU-CCNIC将通过吸引癌症来增强其研究的转化价值和潜在影响 研究倡导者，将成为EAP的成员，并将邀请参加NU-CCNIC研讨会和 现场访问。 ACC将支持每周，每两周，每月和季度研究会议，以促进 NU-CCNIC的沟通，协作和整合，并将进一步支持沟通和广泛的沟通 通过双年一次的讲习班与外部演讲者一起传播知识。在AIM 1中 行政核心将促进并确保整个技术之间的清晰有效的沟通 开发（技术）和研究床（RTB）单位。在AIM 2中，我们将计划并建立常规中心 会议和研究研讨会，以促进NU-CCNIC和更广泛社区的沟通 这对于我们的研究任务和传播至关重要。在AIM 3中，我们将努力增加表示形式和 在NU-CCNIC的生物医学研究人员中，培训代表性不足的少数群体。在AIM 4中，我们将 与癌症研究倡导者合作，以确保患者观点在NU- ccnic。在AIM 5中，我们将与EAP和癌症研究倡导者合作NU-CCNIC评估计划 确保及时取得中心进步，并明智地分配资源。